ID Q728N3_DESVH Unreviewed; 550 AA.
AC Q728N3;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 110.
DE SubName: Full=GGDEF domain/HAMP domain protein {ECO:0000313|EMBL:AAS97042.1};
GN OrderedLocusNames=DVU_2570 {ECO:0000313|EMBL:AAS97042.1};
OS Desulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM
OS B-1760 / Hildenborough).
OC Bacteria; Thermodesulfobacteriota; Desulfovibrionia; Desulfovibrionales;
OC Desulfovibrionaceae; Nitratidesulfovibrio.
OX NCBI_TaxID=882 {ECO:0000313|EMBL:AAS97042.1, ECO:0000313|Proteomes:UP000002194};
RN [1] {ECO:0000313|EMBL:AAS97042.1, ECO:0000313|Proteomes:UP000002194}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 / Hildenborough
RC {ECO:0000313|Proteomes:UP000002194};
RX PubMed=15077118; DOI=10.1038/nbt959;
RA Heidelberg J.F., Seshadri R., Haveman S.A., Hemme C.L., Paulsen I.T.,
RA Kolonay J.F., Eisen J.A., Ward N., Methe B., Brinkac L.M., Daugherty S.C.,
RA Deboy R.T., Dodson R.J., Durkin A.S., Madupu R., Nelson W.C.,
RA Sullivan S.A., Fouts D., Haft D.H., Selengut J., Peterson J.D.,
RA Davidsen T.M., Zafar N., Zhou L., Radune D., Dimitrov G., Hance M.,
RA Tran K., Khouri H., Gill J., Utterback T.R., Feldblyum T.V., Wall J.D.,
RA Voordouw G., Fraser C.M.;
RT "The genome sequence of the anaerobic, sulfate-reducing bacterium
RT Desulfovibrio vulgaris Hildenborough.";
RL Nat. Biotechnol. 22:554-559(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AE017285; AAS97042.1; -; Genomic_DNA.
DR RefSeq; WP_010939840.1; NZ_CABHLV010000001.1.
DR RefSeq; YP_011782.1; NC_002937.3.
DR AlphaFoldDB; Q728N3; -.
DR SMR; Q728N3; -.
DR STRING; 882.DVU_2570; -.
DR PaxDb; 882-DVU_2570; -.
DR EnsemblBacteria; AAS97042; AAS97042; DVU_2570.
DR KEGG; dvu:DVU_2570; -.
DR PATRIC; fig|882.5.peg.2329; -.
DR eggNOG; COG3706; Bacteria.
DR HOGENOM; CLU_000445_134_4_7; -.
DR OrthoDB; 9813903at2; -.
DR PhylomeDB; Q728N3; -.
DR Proteomes; UP000002194; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd12914; PDC1_DGC_like; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002194};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 294..350
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 386..522
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT REGION 525..550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 550 AA; 59058 MW; 8C5959AC0863A72E CRC64;
MKRFDTLQGR LVLFVLLLFG APLLVAPLVF LLFLRQPFVA DVSADLNAEL AHHARVLDGL
LDGYAGRVQV LAATIMLHDD SLLSLEDHFR VVQSATPDFD DIFAVGPDGT VVAGIKAKPG
LALGDRSYIR SALDGRRVVS EVVKSRVSGK PIVVIAAPYR DRAGAIAGAV GGVVDLTRVN
MVLQSLRLRD GGTAFLVGRD GITLTKGRTL GTDEVASLRA LAGDDGRRFM VMQTAEGTDV
LRVARFAKGG EWLLVRELPQ DVALAGQRRA ALVVLLVNSA IVLVLVPFVV RFGRTIVRPT
RLVATLSGRI AAGDFQPECE FVDLAAAPVE IRQLYKNFCT MSARLGEHMR ALERMAVTDQ
LTGLHNRRYV AVEGAKVVDV CWRGGRPCSC LMADIDRFKT INDTYGHEAG DAVLQAFAEV
FRGGLRWSDI GARHGGEEFV VIAPNADTRD AVVIAERLRV DAAALVVEFG GHVIRFTVSV
GVASLDEHGG DGNLLEELLR RADTALYRAK AEGRDRVCVW REGDGDGPCL PGKAPDGATS
ADGDGGRGEA
//
