ID Q72F00_DESVH Unreviewed; 396 AA.
AC Q72F00;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 104.
DE SubName: Full=Saccharopine dehydrogenase {ECO:0000313|EMBL:AAS94901.1};
DE EC=1.5.1.7 {ECO:0000313|EMBL:AAS94901.1};
GN Name=lys1 {ECO:0000313|EMBL:AAS94901.1};
GN OrderedLocusNames=DVU_0418 {ECO:0000313|EMBL:AAS94901.1};
OS Desulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM
OS B-1760 / Hildenborough).
OC Bacteria; Thermodesulfobacteriota; Desulfovibrionia; Desulfovibrionales;
OC Desulfovibrionaceae; Nitratidesulfovibrio.
OX NCBI_TaxID=882 {ECO:0000313|EMBL:AAS94901.1, ECO:0000313|Proteomes:UP000002194};
RN [1] {ECO:0000313|EMBL:AAS94901.1, ECO:0000313|Proteomes:UP000002194}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 / Hildenborough
RC {ECO:0000313|Proteomes:UP000002194};
RX PubMed=15077118; DOI=10.1038/nbt959;
RA Heidelberg J.F., Seshadri R., Haveman S.A., Hemme C.L., Paulsen I.T.,
RA Kolonay J.F., Eisen J.A., Ward N., Methe B., Brinkac L.M., Daugherty S.C.,
RA Deboy R.T., Dodson R.J., Durkin A.S., Madupu R., Nelson W.C.,
RA Sullivan S.A., Fouts D., Haft D.H., Selengut J., Peterson J.D.,
RA Davidsen T.M., Zafar N., Zhou L., Radune D., Dimitrov G., Hance M.,
RA Tran K., Khouri H., Gill J., Utterback T.R., Feldblyum T.V., Wall J.D.,
RA Voordouw G., Fraser C.M.;
RT "The genome sequence of the anaerobic, sulfate-reducing bacterium
RT Desulfovibrio vulgaris Hildenborough.";
RL Nat. Biotechnol. 22:554-559(2004).
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DR EMBL; AE017285; AAS94901.1; -; Genomic_DNA.
DR RefSeq; WP_010937725.1; NC_002937.3.
DR RefSeq; YP_009642.1; NC_002937.3.
DR AlphaFoldDB; Q72F00; -.
DR SMR; Q72F00; -.
DR STRING; 882.DVU_0418; -.
DR PaxDb; 882-DVU_0418; -.
DR EnsemblBacteria; AAS94901; AAS94901; DVU_0418.
DR KEGG; dvu:DVU_0418; -.
DR PATRIC; fig|882.5.peg.397; -.
DR eggNOG; COG1748; Bacteria.
DR HOGENOM; CLU_032114_0_0_7; -.
DR OrthoDB; 9769367at2; -.
DR PhylomeDB; Q72F00; -.
DR Proteomes; UP000002194; Chromosome.
DR GO; GO:0004754; F:saccharopine dehydrogenase (NAD+, L-lysine-forming) activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032095; Sacchrp_dh-like_C.
DR InterPro; IPR005097; Sacchrp_dh_NADP.
DR PANTHER; PTHR43796; CARBOXYNORSPERMIDINE SYNTHASE; 1.
DR PANTHER; PTHR43796:SF2; CARBOXYNORSPERMIDINE SYNTHASE; 1.
DR Pfam; PF16653; Sacchrp_dh_C; 1.
DR Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:AAS94901.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002194}.
FT DOMAIN 4..137
FT /note="Saccharopine dehydrogenase NADP binding"
FT /evidence="ECO:0000259|Pfam:PF03435"
FT DOMAIN 141..389
FT /note="Saccharopine dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16653"
SQ SEQUENCE 396 AA; 44376 MW; F019D58B4C9646D1 CRC64;
MAKVLIIGAG GVGGVVAHKC AQVADVFSEI VLASRTKSKC DAIAADIKAR TGRTIETAQV
DADNVPELVA LIKACKPAMV LNLALPYQDL TIMDACLETG VHYLDTANYE PLDEAKFEYK
WQWAYQERFR EKGLMALLGS GFDPGVTNVF CAYAQKHLFD EIHVLDIIDC NAGDHGHPFA
TNFNPEINIR EVTARGRYWE RGEWVETDPL SWAMNYDFPE GIGPKKCFLM YHEELESLVQ
NLKGLKRARF WMTFSDNYLN HLKVLENVGM TRIDEVEHNG HKIVPIQFLR SLLPDPASLG
PRTKGRTCIG CLMQGVKDGK EKTAYIYNIC DHEACYREVG SQAISYTTGV PAMIGAMMML
TGKWTGQGVF NMEQMDPDPF MEKLNLHGLP WVVVEK
//
