ID Q73L03_TREDE Unreviewed; 944 AA.
AC Q73L03;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 08-MAY-2019, entry version 98.
DE RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN Name=feoB {ECO:0000313|EMBL:AAS12576.1};
GN OrderedLocusNames=TDE_2063 {ECO:0000313|EMBL:AAS12576.1};
OS Treponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222).
OC Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae; Treponema.
OX NCBI_TaxID=243275 {ECO:0000313|EMBL:AAS12576.1, ECO:0000313|Proteomes:UP000008212};
RN [1] {ECO:0000313|EMBL:AAS12576.1, ECO:0000313|Proteomes:UP000008212}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35405 / CIP 103919 / DSM 14222
RC {ECO:0000313|Proteomes:UP000008212};
RX PubMed=15064399; DOI=10.1073/pnas.0307639101;
RA Seshadri R., Myers G.S., Tettelin H., Eisen J.A., Heidelberg J.F.,
RA Dodson R.J., Davidsen T.M., DeBoy R.T., Fouts D.E., Haft D.H.,
RA Selengut J., Ren Q., Brinkac L.M., Madupu R., Kolonay J., Durkin S.A.,
RA Daugherty S.C., Shetty J., Shvartsbeyn A., Gebregeorgis E., Geer K.,
RA Tsegaye G., Malek J., Ayodeji B., Shatsman S., McLeod M.P., Smajs D.,
RA Howell J.K., Pal S., Amin A., Vashisth P., McNeill T.Z., Xiang Q.,
RA Sodergren E., Baca E., Weinstock G.M., Norris S.J., Fraser C.M.,
RA Paulsen I.T.;
RT "Comparison of the genome of the oral pathogen Treponema denticola
RT with other spirochete genomes.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:5646-5651(2004).
CC -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC system. {ECO:0000256|RuleBase:RU362098}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|RuleBase:RU362098}.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC {ECO:0000256|RuleBase:RU362098}.
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DR EMBL; AE017226; AAS12576.1; -; Genomic_DNA.
DR RefSeq; NP_972665.1; NC_002967.9.
DR RefSeq; WP_002679857.1; NC_002967.9.
DR STRING; 243275.TDE_2063; -.
DR EnsemblBacteria; AAS12576; AAS12576; TDE_2063.
DR GeneID; 2741190; -.
DR KEGG; tde:TDE2063; -.
DR PATRIC; fig|243275.7.peg.1947; -.
DR eggNOG; ENOG4105CE1; Bacteria.
DR eggNOG; COG0370; LUCA.
DR KO; K04759; -.
DR OrthoDB; 304844at2; -.
DR BioCyc; TDEN243275:G1G0Q-2102-MONOMER; -.
DR Proteomes; UP000008212; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR CDD; cd01879; FeoB; 1.
DR InterPro; IPR003373; Fe2_transport_prot-B.
DR InterPro; IPR011640; Fe2_transport_prot_B_C.
DR InterPro; IPR041069; FeoB_Cyto.
DR InterPro; IPR030389; G_FEOB_dom.
DR InterPro; IPR011642; Gate_dom.
DR InterPro; IPR006073; GTP_binding_domain.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR Pfam; PF07664; FeoB_C; 1.
DR Pfam; PF17910; FeoB_Cyto; 1.
DR Pfam; PF02421; FeoB_N; 1.
DR Pfam; PF07670; Gate; 2.
DR PRINTS; PR00326; GTP1OBG.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR00437; feoB; 1.
DR TIGRFAMs; TIGR00231; small_GTP; 1.
DR PROSITE; PS51711; G_FEOB; 1.
PE 3: Inferred from homology;
KW Complete proteome {ECO:0000313|Proteomes:UP000008212};
KW GTP-binding {ECO:0000256|RuleBase:RU362098};
KW Ion transport {ECO:0000256|RuleBase:RU362098};
KW Iron {ECO:0000256|RuleBase:RU362098};
KW Iron transport {ECO:0000256|RuleBase:RU362098};
KW Membrane {ECO:0000256|RuleBase:RU362098};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW Reference proteome {ECO:0000313|Proteomes:UP000008212};
KW Transmembrane {ECO:0000256|RuleBase:RU362098};
KW Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW Transport {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 296 322 Helical. {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 328 347 Helical. {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 368 390 Helical. {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 425 454 Helical. {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 481 500 Helical. {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 512 537 Helical. {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 543 564 Helical. {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 602 621 Helical. {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 887 906 Helical. {ECO:0000256|RuleBase:RU362098}.
FT TRANSMEM 918 938 Helical. {ECO:0000256|RuleBase:RU362098}.
FT DOMAIN 5 167 FeoB-type G. {ECO:0000259|PROSITE:
FT PS51711}.
SQ SEQUENCE 944 AA; 105128 MW; BA5462684DA4457E CRC64;
MKKEKINIAF AGQPNSGKST LFNMMTGAHQ HVANYPGITV EKKTGEYFAL DQSVFITDLP
GTYSLTSYSP EERVTRNFIL REKPELLVNI ADASNLERHL YLTFQLLEMN CPIVMYLNKM
DSAKNAGLQI DVDKVSSLLG IPIIAGSAKK KEKINELKEL ISKTAESSEP QKPFMLTYGK
DMESYLEKIV EKLKASAKDE FFSIPLRWLA IKLCEKDSAV IEEEGKNFTN FDSILTFIKE
IEAEHKEKHK HSFEIEIALA RSAAAKKIVE AAVSKKELEQ KAVESLNIKR KVTETIAALI
LCFVTYEILD SLFLLLPIPI VANNILRLIL SLAGAFAFTG GAALIYTKGG SGSINSTDRI
DKVLCHKVYG LLILVELVLV FYWITVVLGY KMTDKVFPIF KFVRAIVSQL IYPEGLINEG
PLRGLFLSGI IDGAIMILNY VPIFFCLFAL IAFLEDVGYM ARLAFIMDRI LRKFGLHGQS
TLPMILSGVI MGGCVVPGVM STRTIRDDKS RLVTILILPL LNCMAKIPFY VLITGIFFTS
YQWIVLGGIS FFTLIVALIV AKYFSLYVVH GKPEPFVLEL PAYNMPTLRG VLTRTFERLW
SFIKKVATTV VAVSVIIWAG VNFPSLSSEK TAQYEARKAA YIQDFAGKLN NSYSQYFASE
KGFIEYQRLT EKLYLYDAIN LFGGAKGMEK NINRLFLQNP EMTKIALKGK IELGSNIGAF
KNYFDMYSSA KKDFDKAYND AQEFQKPILK ASFYAYWQKL NPYFFALVRT GKVKISGTAV
IDSEAAAAAK AIRPASADLK LISVQLRKET LENSVLGYLG KAMEPVTKYA GFDWKVNIAI
LGSFAAKEAL VSTLGTIYSV ESSSEDSGKV LEARIQDKET GLTPLDGLTI MILIALFPPC
IATVMATKTE TQSVGWTLFS VMYPVVLSSL VAVLVFQLGR LFGF
//
