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Database: UniProt
Entry: Q73N05_TREDE
LinkDB: Q73N05_TREDE
Original site: Q73N05_TREDE 
ID   Q73N05_TREDE            Unreviewed;       172 AA.
AC   Q73N05;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   27-MAR-2024, entry version 79.
DE   SubName: Full=Rod shape-determining protein MreD {ECO:0000313|EMBL:AAS11868.1};
GN   Name=mreD {ECO:0000313|EMBL:AAS11868.1};
GN   OrderedLocusNames=TDE_1351 {ECO:0000313|EMBL:AAS11868.1};
OS   Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153
OS   / KCTC 15104).
OC   Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Treponemataceae;
OC   Treponema.
OX   NCBI_TaxID=243275 {ECO:0000313|EMBL:AAS11868.1, ECO:0000313|Proteomes:UP000008212};
RN   [1] {ECO:0000313|EMBL:AAS11868.1, ECO:0000313|Proteomes:UP000008212}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104
RC   {ECO:0000313|Proteomes:UP000008212};
RX   PubMed=15064399; DOI=10.1073/pnas.0307639101;
RA   Seshadri R., Myers G.S., Tettelin H., Eisen J.A., Heidelberg J.F.,
RA   Dodson R.J., Davidsen T.M., DeBoy R.T., Fouts D.E., Haft D.H., Selengut J.,
RA   Ren Q., Brinkac L.M., Madupu R., Kolonay J., Durkin S.A., Daugherty S.C.,
RA   Shetty J., Shvartsbeyn A., Gebregeorgis E., Geer K., Tsegaye G., Malek J.,
RA   Ayodeji B., Shatsman S., McLeod M.P., Smajs D., Howell J.K., Pal S.,
RA   Amin A., Vashisth P., McNeill T.Z., Xiang Q., Sodergren E., Baca E.,
RA   Weinstock G.M., Norris S.J., Fraser C.M., Paulsen I.T.;
RT   "Comparison of the genome of the oral pathogen Treponema denticola with
RT   other spirochete genomes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:5646-5651(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the MreD family.
CC       {ECO:0000256|ARBA:ARBA00007776}.
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DR   EMBL; AE017226; AAS11868.1; -; Genomic_DNA.
DR   RefSeq; NP_971957.1; NC_002967.9.
DR   RefSeq; WP_002671465.1; NC_002967.9.
DR   AlphaFoldDB; Q73N05; -.
DR   STRING; 243275.TDE_1351; -.
DR   PaxDb; 243275-TDE_1351; -.
DR   GeneID; 2739452; -.
DR   KEGG; tde:TDE_1351; -.
DR   PATRIC; fig|243275.7.peg.1299; -.
DR   eggNOG; COG2891; Bacteria.
DR   HOGENOM; CLU_132534_2_2_12; -.
DR   OrthoDB; 5184389at2; -.
DR   Proteomes; UP000008212; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   InterPro; IPR017225; Cell_shape_determin_MreD_prd.
DR   InterPro; IPR007227; Cell_shape_determining_MreD.
DR   NCBIfam; TIGR03426; shape_MreD; 1.
DR   Pfam; PF04093; MreD; 1.
DR   PIRSF; PIRSF037497; MreD_Clostridium/Treponema_prd; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Cell shape {ECO:0000256|ARBA:ARBA00022960};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008212};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        36..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        65..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        97..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        134..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   172 AA;  19312 MW;  FCD4EAE3270469C0 CRC64;
     MKKVILWTSL SVFFITLLQT AIFSHISFFT VLPDLVLLTV IYIAISNGSL TGLICGFIAG
     LLADFLSAAP IGLHSFIFTL TGYLVGKFYG IYNLNKVIFP CILGGLGFVF KVLLLFVLKI
     LFGQNIHTYN IFSINFAIEA AVNIFFTPFV FLFFNLFPQA FISRSIVQYE KY
//
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