ID Q73XP2_MYCPA Unreviewed; 946 AA.
AC Q73XP2;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=Rne {ECO:0000313|EMBL:AAS04584.1};
GN Name=rne {ECO:0000313|EMBL:AAS04584.1};
GN OrderedLocusNames=MAP_2267c {ECO:0000313|EMBL:AAS04584.1};
OS Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)
OS (Mycobacterium paratuberculosis).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium avium complex (MAC).
OX NCBI_TaxID=262316 {ECO:0000313|EMBL:AAS04584.1, ECO:0000313|Proteomes:UP000000580};
RN [1] {ECO:0000313|EMBL:AAS04584.1, ECO:0000313|Proteomes:UP000000580}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-968 / K-10 {ECO:0000313|Proteomes:UP000000580};
RX PubMed=16116077; DOI=10.1073/pnas.0505662102;
RA Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N.,
RA Kanjilal S., Kapur V.;
RT "The complete genome sequence of Mycobacterium avium subspecies
RT paratuberculosis.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR EMBL; AE016958; AAS04584.1; -; Genomic_DNA.
DR RefSeq; WP_010949543.1; NZ_CP106873.1.
DR AlphaFoldDB; Q73XP2; -.
DR STRING; 262316.MAP_2267c; -.
DR KEGG; mpa:MAP_2267c; -.
DR PATRIC; fig|262316.17.peg.2410; -.
DR eggNOG; COG1530; Bacteria.
DR HOGENOM; CLU_003468_2_0_11; -.
DR Proteomes; UP000000580; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd04453; S1_RNase_E; 1.
DR Gene3D; 1.10.10.2480; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR019307; RNA-bd_AU-1/RNase_E/G.
DR InterPro; IPR004659; RNase_E/G.
DR InterPro; IPR003029; S1_domain.
DR NCBIfam; TIGR00757; RNaseEG; 1.
DR PANTHER; PTHR30001; RIBONUCLEASE; 1.
DR PANTHER; PTHR30001:SF0; RIBONUCLEASE G; 1.
DR Pfam; PF10150; RNase_E_G; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS50126; S1; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000000580};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 369..446
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 68..308
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 753..946
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..149
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..200
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..219
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..283
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 285..308
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 823..838
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 839..912
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 946 AA; 102172 MW; 7F85B4C92A2D1E86 CRC64;
MVDGAPTADP SEESTRSGDL PDRLRVHSLA RTLGTTSKRV LDALSELDGR VRSAHSTVDR
EDAVRVRDLL AAQPSAEPEP AAEDAASGGP DAGIAGEPES RLLLETPDAT ERPHYMPLFV
APQPLESSDD DGDADETADS DDSDGDDDEQ ADRPSSRRRR RGRRGRGRGR GEQGGSDGPG
DGDDDEPQNR GKKGGQSDGD DDSDGQDAED ADDSDTGDDG SADGGNRRRR RRRRRKSGSG
DDNEDGPSPD DPPNTVVHER PPRNGKNGGD DGNGSSSSEI KGIDGSTRLE AKRQRRRDGR
DAGRRRPPVL TEAEFLARRE AVERVMVVRD RIRTEPPHQG SRYTQIAVLE DGIVVEHFVT
SAASASLVGN IYLGIVQNVL PSMEAAFVDI GRGRNGVLYA GEVNWEAAGL GGSDRKIEQA
LKPGDYVVVQ VSKDPVGHKG ARLTTQVSLA GRYLVYVPGA SSTGISRKLP DTERQRLKEI
LREVVPSDAG VIIRTASEGV KEDDIRGDVT RLQERWKQIE AKAIEIKEKA AGAAVALYEE
PDVLVKVIRD LFNEDFAGLI VSGDDAWNTI NEYVNSVAPD LVSKVTKYEP ATGPDGTPGP
DVFAVHRIDE QLAKAMDRKV WLPSGGTLVI DRTEAMTVID VNTGKFTGSG GNLEQTVTKN
NLEAAEEIVR QLRLRDIGGI VVIDFIDMVL ESNRDLVLRR LTEALARDRT RHQVSEVTSL
GLVQLTRKRL GTGLVEAFST SCPNCGGRGI LLHADPVDSA PSNGRKSESG GRRGRRKKSK
AEEPVVAKVP VHSPGEHPMF KAMAAGSSTQ AASDEDESAA EEAGDELERK KAARAEELEA
AEDTEDLEDT EDDDEDSDDS DDEDLDDEDI DDEEDLGDDD EDLELDDDDL DTEDSDDSDD
SDDSEDSDDS EDQRDPAAER PGVSALGRPR RRRAAGRPAG PPIHAD
//
