ID Q743A5_MYCPA Unreviewed; 467 AA.
AC Q743A5;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE RecName: Full=AMP-dependent synthetase {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=MAP_0680 {ECO:0000313|EMBL:AAS02997.1};
OS Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)
OS (Mycobacterium paratuberculosis).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium avium complex (MAC).
OX NCBI_TaxID=262316 {ECO:0000313|EMBL:AAS02997.1, ECO:0000313|Proteomes:UP000000580};
RN [1] {ECO:0000313|EMBL:AAS02997.1, ECO:0000313|Proteomes:UP000000580}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-968 / K-10 {ECO:0000313|Proteomes:UP000000580};
RX PubMed=16116077; DOI=10.1073/pnas.0505662102;
RA Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N.,
RA Kanjilal S., Kapur V.;
RT "The complete genome sequence of Mycobacterium avium subspecies
RT paratuberculosis.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005).
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DR EMBL; AE016958; AAS02997.1; -; Genomic_DNA.
DR RefSeq; WP_003873059.1; NZ_CP106873.1.
DR AlphaFoldDB; Q743A5; -.
DR STRING; 262316.MAP_0680; -.
DR KEGG; mpa:MAP_0680; -.
DR PATRIC; fig|262316.17.peg.715; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_0_11; -.
DR Proteomes; UP000000580; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR24096:SF149; 4-COUMARATE--COA LIGASE 1-RELATED; 1.
DR PANTHER; PTHR24096; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000580}.
FT DOMAIN 5..329
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 378..451
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 467 AA; 49828 MW; E7803ACB4EFE5FC8 CRC64;
MTEPAALVFE ERRFSVPELD ALADGWAAAL AKDGVTAGRR VAVMTSNRPE FLAVLLAIWR
LAATAVLISP AWKRDEVEHA LALTDPGHAV GDHPVLAGLM PMLHLDEPVP PAQPTAGAPP
RAGDAVLVFS SGTTGLPKAV RHTHASLDEA VRHWREALRL TRRDRIQVAT PPSHILGLLN
LLTALKTGAC VRLHPRFDID KVLHHIESDR VTVEMAVAPI ALAIASHPDL ESYDLSSLRY
IVWGATPVNA EVAQTVTRRT GVGWLPAYGT TELPVIACNP IEDARLDTVG RPVPGVEVRV
VSLASGEPAG AGEVGEIQAR SASLMAGYLP GEATGEAIRD GWYRTGDAGW LDTGGWLRIT
DRLKEMIKVR GFQVAPAEIE AVLQGHPAVA DCAVFGVPDG LNGEAVVAAV AVSAPVDVTE
LTALVRQKLA SYKHLSRVVV VPEIPRLPSG KVLRRVLKER HGCTSDS
//
