ID Q744P3_MYCPA Unreviewed; 502 AA.
AC Q744P3;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE RecName: Full=HTH cro/C1-type domain-containing protein {ECO:0000259|PROSITE:PS50943};
GN OrderedLocusNames=MAP_0298 {ECO:0000313|EMBL:AAS02615.1};
OS Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)
OS (Mycobacterium paratuberculosis).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium avium complex (MAC).
OX NCBI_TaxID=262316 {ECO:0000313|EMBL:AAS02615.1, ECO:0000313|Proteomes:UP000000580};
RN [1] {ECO:0000313|EMBL:AAS02615.1, ECO:0000313|Proteomes:UP000000580}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-968 / K-10 {ECO:0000313|Proteomes:UP000000580};
RX PubMed=16116077; DOI=10.1073/pnas.0505662102;
RA Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N.,
RA Kanjilal S., Kapur V.;
RT "The complete genome sequence of Mycobacterium avium subspecies
RT paratuberculosis.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005).
CC -!- SIMILARITY: Belongs to the short-chain fatty acyl-CoA assimilation
CC regulator (ScfR) family. {ECO:0000256|ARBA:ARBA00007227}.
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DR EMBL; AE016958; AAS02615.1; -; Genomic_DNA.
DR AlphaFoldDB; Q744P3; -.
DR STRING; 262316.MAP_0298; -.
DR KEGG; mpa:MAP_0298; -.
DR eggNOG; COG1396; Bacteria.
DR eggNOG; COG3800; Bacteria.
DR HOGENOM; CLU_046383_0_0_11; -.
DR Proteomes; UP000000580; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR026281; HTH_RamB.
DR InterPro; IPR010359; IrrE_HExxH.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR018653; ScfR_C.
DR PANTHER; PTHR46797; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR PANTHER; PTHR46797:SF23; HTH-TYPE TRANSCRIPTIONAL REGULATOR PRPR; 1.
DR Pfam; PF01381; HTH_3; 1.
DR Pfam; PF06114; Peptidase_M78; 1.
DR Pfam; PF09856; ScfRs; 1.
DR PIRSF; PIRSF019251; Rv0465c; 1.
DR SMART; SM00530; HTH_XRE; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000000580};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 38..92
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
SQ SEQUENCE 502 AA; 55821 MW; 2303AA81E300489B CRC64;
MRCKSVILRP CPTVFANFVK GAGRRVVRVA KTFAGARLRR LREEQGLTQV ALARALGLST
SYVNQLENDQ RPITVPVLLT LTERFDLPTQ YFAPDSDARL IADLREVLAE TPATPGQVEE
LVARMPAIGQ TLVNLHRRLH DTTADLEALY SRANLDISDT PGLPHQPMPF EEVRDFFYDR
KNYIGELDVA AEEMFDHNRL RIGGLDGQLA RLLGEQLGVA VVIDDGQLLA PNSKRLFDPE
SKTVYLARWL HPGQRAFQLA TQIALLTQPE LITAIIAGDD QLSDDARGVA RIGLANYFAG
ALLLPYRRFL DAAERVRYDI DQLSRRFEVG FETVCHRLST LQRPNARGVP FIFVRTDSAG
NISKRQSATA FHFSRVGGNC PLWVVHHAFS RPGQFLTQVA QMPDDRTYFW IARTTSGGPS
RYLGPHKSFA IGLGCDVDHA DKLIYSVGID LRDTESIVPI GAGCKICDRA ACPQRAFPYL
GRPVSVDPHR STDLPYPPAI TP
//
