ID Q74FM3_GEOSL Unreviewed; 566 AA.
AC Q74FM3;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2012, sequence version 2.
DT 27-MAR-2024, entry version 90.
DE SubName: Full=Methyl-accepting chemotaxis sensory transducer, class 40+24H {ECO:0000313|EMBL:AAR33914.2};
GN Name=mcp64H-1 {ECO:0000313|EMBL:AAR33914.2};
GN OrderedLocusNames=GSU0583 {ECO:0000313|EMBL:AAR33914.2};
OS Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA).
OC Bacteria; Thermodesulfobacteriota; Desulfuromonadia; Geobacterales;
OC Geobacteraceae; Geobacter.
OX NCBI_TaxID=243231 {ECO:0000313|EMBL:AAR33914.2, ECO:0000313|Proteomes:UP000000577};
RN [1] {ECO:0000313|EMBL:AAR33914.2, ECO:0000313|Proteomes:UP000000577}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51573 / DSM 12127 / PCA
RC {ECO:0000313|Proteomes:UP000000577};
RX PubMed=14671304; DOI=10.1126/science.1088727;
RA Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.,
RA Heidelberg J.F., Wu D., Wu M., Ward N., Beanan M.J., Dodson R.J.,
RA Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S., Gwinn M.,
RA Kolonay J.F., Sullivan S.A., Haft D.H., Selengut J., Davidsen T.M.,
RA Zafar N., White O., Tran B., Romero C., Forberger H.A., Weidman J.,
RA Khouri H., Feldblyum T.V., Utterback T.R., Van Aken S.E., Lovley D.R.,
RA Fraser C.M.;
RT "Genome of Geobacter sulfurreducens: metal reduction in subsurface
RT environments.";
RL Science 302:1967-1969(2003).
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE017180; AAR33914.2; -; Genomic_DNA.
DR RefSeq; NP_951641.2; NC_002939.5.
DR RefSeq; WP_010941246.1; NC_002939.5.
DR AlphaFoldDB; Q74FM3; -.
DR SMR; Q74FM3; -.
DR STRING; 243231.GSU0583; -.
DR EnsemblBacteria; AAR33914; AAR33914; GSU0583.
DR KEGG; gsu:GSU0583; -.
DR PATRIC; fig|243231.5.peg.581; -.
DR eggNOG; COG0840; Bacteria.
DR HOGENOM; CLU_000445_99_0_7; -.
DR InParanoid; Q74FM3; -.
DR OrthoDB; 5523945at2; -.
DR Proteomes; UP000000577; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IBA:GO_Central.
DR GO; GO:0006935; P:chemotaxis; IBA:GO_Central.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR PANTHER; PTHR43531:SF11; METHYL-ACCEPTING CHEMOTAXIS PROTEIN 3; 1.
DR PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 3.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000577};
KW Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 46..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 68..120
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 209..445
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
SQ SEQUENCE 566 AA; 60827 MW; 5BAD07007FB26E4B CRC64;
MAKNLSLGSR LIRFSLTAGF IVGTAGAVMA LNYAPAAGYD RGHAHLLAGM LGCNALLSLF
ALWMLSARKL VVRVNNLASA MDRGAEGDLT VTVTDESSDE LGQLTDNFNA MFGRLAGMVT
RVKEAVEELR AISATVKDAV ERGLDTAEVQ TGAVQRTTDG IRAIDRSVNE VAQSVESLSR
TASENAAAIV QMSTSIEVVA EHMEGLAREV DEVSSSIIQM AAAEKEIGRS VRVLMEDASR
TASLVAEMDL SIRQVEKSAL ETAAISEEVL RDAELGRDSV DRTISGISEI RRSSRSASDT
ITTLSHRVGD IGTIISVINE IAEQTKLLAL NASIIAAQAG EHGKGFAVVA NEIKELAKRT
TSSTGEIAEI ISGLREETVR AVQAIKQAED RIGEGETLSY RSGEALEKIV DGVKMAVDQV
GEIARTTVEQ AQGSENMRRA MERVAEMVEQ IMRATQEQAH GTELITEAAD RMKSLTGRVF
SSTREQRDTS THIVRSSEGV THMISTIRQA SQVQAENSQK IVEAVENMET TAVNGLDTTR
LMEEAVSRLA RQTEGLTEAM AGFKVR
//
