ID Q79Z47_STRAW Unreviewed; 529 AA.
AC Q79Z47;
DT 11-JUL-2012, integrated into UniProtKB/TrEMBL.
DT 11-JUL-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Secreted protein {ECO:0000313|EMBL:BAC72862.1};
GN ORFNames=SAVERM_5150 {ECO:0000313|EMBL:BAC72862.1};
OS Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS 14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC72862.1, ECO:0000313|Proteomes:UP000000428};
RN [1] {ECO:0000313|EMBL:BAC72862.1, ECO:0000313|Proteomes:UP000000428}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX PubMed=11572948; DOI=10.1073/pnas.211433198;
RA Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA Sakaki Y., Hattori M.;
RT "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT deducing the ability of producing secondary metabolites.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN [2] {ECO:0000313|EMBL:BAC72862.1, ECO:0000313|Proteomes:UP000000428}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX PubMed=12692562; DOI=10.1038/nbt820;
RA Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA Sakaki Y., Hattori M., Omura S.;
RT "Complete genome sequence and comparative analysis of the industrial
RT microorganism Streptomyces avermitilis.";
RL Nat. Biotechnol. 21:526-531(2003).
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DR EMBL; BA000030; BAC72862.1; -; Genomic_DNA.
DR RefSeq; WP_010986554.1; NZ_JZJK01000072.1.
DR AlphaFoldDB; Q79Z47; -.
DR KEGG; sma:SAVERM_5150; -.
DR eggNOG; COG0457; Bacteria.
DR HOGENOM; CLU_026568_1_0_11; -.
DR OrthoDB; 5477158at2; -.
DR Proteomes; UP000000428; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR12558; CELL DIVISION CYCLE 16,23,27; 1.
DR PANTHER; PTHR12558:SF13; CELL DIVISION CYCLE PROTEIN 27 HOMOLOG; 1.
DR Pfam; PF13432; TPR_16; 1.
DR SMART; SM00028; TPR; 5.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000428};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 244..277
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 469..529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 474..488
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 514..529
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 529 AA; 55825 MW; 7EE40A88E752A48C CRC64;
MEIEQQQPLP SERGLSPVAR RALIGAITGC FVLGGVLMLL PPAGREPAAP PAPAAGPMAG
PVAQAKAAVG AGVPVALPAL AALVTDHETH LRAHPRDARS WAVLGAAYVA QGKGTADAAY
FPKAEEALRT SLNVAPRRNA EALGALAALA NARGDYREAK QWGEAAVKMA PKQWPAYAQL
IDAYDGLGDY KATGKTLDKL LGLRAGPAAA ARAAQVYRAR GWREDAAAAI ADATARAGSP
AEQAVYWQQA GELAWERGEP EQALRYFETA LRTDPDRHAA LAGQGRALAA LGRTSDAVNA
YRAALAKQPL AAYAVELGEL YESQGLGGAA QVQYYLVRER VRQDAAGGVN NRLVVGQFEA
DHGDAEVAVR ELREEWKRQP SIRVADALGW ALHRAGQDQE ALGFATKAMD KEHGGGVRSA
LYAYHRGEIE RALDQLAPAR RHLAEALRIN PHFSPWFAPM AKETLAELGE PPAEGLPGDE
EVEAAEAEAA EAAEAAQTPE AAESVDPAQT EQVPPPGAST PVPQEPEAR
//
