ID Q7AKR4_STRCO Unreviewed; 341 AA.
AC Q7AKR4;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 100.
DE RecName: Full=GST C-terminal domain-containing protein {ECO:0000259|PROSITE:PS50405};
GN OrderedLocusNames=SCO0777 {ECO:0000313|EMBL:CAC14342.1};
GN ORFNames=3SCF60.09 {ECO:0000313|EMBL:CAC14342.1};
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226 {ECO:0000313|EMBL:CAC14342.1, ECO:0000313|Proteomes:UP000001973};
RN [1] {ECO:0000313|EMBL:CAC14342.1, ECO:0000313|Proteomes:UP000001973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145
RC {ECO:0000313|Proteomes:UP000001973};
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL939106; CAC14342.1; -; Genomic_DNA.
DR RefSeq; NP_625079.1; NC_003888.3.
DR RefSeq; WP_003978084.1; NZ_VNID01000004.1.
DR AlphaFoldDB; Q7AKR4; -.
DR SMR; Q7AKR4; -.
DR STRING; 100226.gene:17758360; -.
DR PaxDb; 100226-SCO0777; -.
DR PATRIC; fig|100226.15.peg.768; -.
DR eggNOG; COG0435; Bacteria.
DR HOGENOM; CLU_037263_1_0_11; -.
DR InParanoid; Q7AKR4; -.
DR OrthoDB; 9769158at2; -.
DR PhylomeDB; Q7AKR4; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0004364; F:glutathione transferase activity; IBA:GO_Central.
DR CDD; cd03190; GST_C_Omega_like; 1.
DR Gene3D; 1.20.1050.10; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR047047; GST_Omega-like_C.
DR InterPro; IPR016639; GST_Omega/GSH.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR32419:SF6; GLUTATHIONE S-TRANSFERASE OMEGA-LIKE 1-RELATED; 1.
DR PANTHER; PTHR32419; GLUTATHIONYL-HYDROQUINONE REDUCTASE; 1.
DR Pfam; PF13410; GST_C_2; 1.
DR PIRSF; PIRSF015753; GST; 1.
DR SFLD; SFLDG01206; Xi.1; 1.
DR SFLD; SFLDG01148; Xi_(cytGST); 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS50405; GST_CTER; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001973}.
FT DOMAIN 157..287
FT /note="GST C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50405"
FT REGION 314..341
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 327..341
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 52
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR015753-1"
FT ACT_SITE 183
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR015753-1"
SQ SEQUENCE 341 AA; 38106 MW; 6F3732F0D48A70DC CRC64;
MSGDDGTPGN SGYGKKAFKR SRSHFADRIT ADGRDGWPVE AGRYRLVVSR ACPWASRALV
SRRLLGLEDA LSLAVADPVQ DDRSWRFTLD PDGRDPVLGI RYLGEAYDRR ETGYPGGVSV
PAVVDVPSGA LVTNDYQQIT LDLATEWTAL HRPGAPDLYP RALRDEIDEV MAGVYEDVNN
GVYRAGFATG QEEYEAACAG VFRRLEQLTP RLERQRYLVG DTITEADIRL FTTLVRFDAV
YHGHFKCNRW KLTENPVLWA YVRDLFQTPG FGDTVDFDHI KRHYYQVHTG INPTGIVPLG
PDLAGWLTPH HRQELGGRPF GEGTPPEPVR AEEEVPARGR P
//
