ID Q7CTM2_AGRFC Unreviewed; 489 AA.
AC Q7CTM2;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 2.
DT 27-MAR-2024, entry version 121.
DE RecName: Full=HTH lysR-type domain-containing protein {ECO:0000259|PROSITE:PS50931};
GN OrderedLocusNames=Atu3917 {ECO:0000313|EMBL:AAK89502.2};
OS Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens
OS (strain C58)).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC Agrobacterium tumefaciens complex.
OX NCBI_TaxID=176299 {ECO:0000313|EMBL:AAK89502.2, ECO:0000313|Proteomes:UP000000813};
RN [1] {ECO:0000313|EMBL:AAK89502.2, ECO:0000313|Proteomes:UP000000813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970 {ECO:0000313|Proteomes:UP000000813};
RX PubMed=11743193; DOI=10.1126/science.1066804;
RA Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K.,
RA Zhou Y., Chen L., Wood G.E., Almeida N.F.Jr., Woo L., Chen Y.,
RA Paulsen I.T., Eisen J.A., Karp P.D., Bovee D.Sr., Chapman P.,
RA Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R.,
RA Li M.J., McClelland E., Palmieri A., Raymond C., Rouse G.,
RA Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y.,
RA Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S.,
RA Hendrick C., Zhao Z.Y., Dolan M., Chumley F., Tingey S.V., Tomb J.F.,
RA Gordon M.P., Olson M.V., Nester E.W.;
RT "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT C58.";
RL Science 294:2317-2323(2001).
RN [2] {ECO:0000313|EMBL:AAK89502.2, ECO:0000313|Proteomes:UP000000813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970 {ECO:0000313|Proteomes:UP000000813};
RX PubMed=11743194; DOI=10.1126/science.1066803;
RA Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B.,
RA Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K.,
RA Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M.,
RA Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C.,
RA Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
RT "Genome sequence of the plant pathogen and biotechnology agent
RT Agrobacterium tumefaciens C58.";
RL Science 294:2323-2328(2001).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; AE007870; AAK89502.2; -; Genomic_DNA.
DR RefSeq; NP_356717.2; NC_003063.2.
DR RefSeq; WP_010973427.1; NC_003063.2.
DR AlphaFoldDB; Q7CTM2; -.
DR STRING; 176299.Atu3917; -.
DR EnsemblBacteria; AAK89502; AAK89502; Atu3917.
DR GeneID; 66224175; -.
DR KEGG; atu:Atu3917; -.
DR PATRIC; fig|176299.10.peg.3741; -.
DR eggNOG; COG0547; Bacteria.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_043389_0_0_5; -.
DR OrthoDB; 8455878at2; -.
DR PhylomeDB; Q7CTM2; -.
DR BioCyc; AGRO:ATU3917-MONOMER; -.
DR Proteomes; UP000000813; Chromosome linear.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.1030.10; Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR017459; Glycosyl_Trfase_fam3_N_dom.
DR InterPro; IPR036320; Glycosyl_Trfase_fam3_N_dom_sf.
DR InterPro; IPR035902; Nuc_phospho_transferase.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30118; HTH-TYPE TRANSCRIPTIONAL REGULATOR LEUO-RELATED; 1.
DR PANTHER; PTHR30118:SF15; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF02885; Glycos_trans_3N; 1.
DR Pfam; PF00126; HTH_1; 1.
DR SUPFAM; SSF52418; Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain; 1.
DR SUPFAM; SSF47648; Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Nodulation {ECO:0000256|ARBA:ARBA00022458};
KW Reference proteome {ECO:0000313|Proteomes:UP000000813};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 22..77
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 489 AA; 53868 MW; 1C2E2F82604A1A72 CRC64;
MTTGKRKAEP VSTAKPDRLG QLKLLVAFDA LLREGSVSRA AAGMGLPTSS MSRILQQLRE
KYGDQLFLRT GQGLRPTPFA ENMRLRIRSL AAEAENLMDY SQQKPEGPAA PDKSGWEQPL
LMKAPPLSLR PSVVLEGQPT PEHIADRLAR IGHNADPRHR LAKYIATSAM GIGNSRPLAQ
GEAMDALSII LEGEADPIQV GALLATMHYR GVTAAELAGF IEAMWQHIER DRQRPASVDL
DWPAYMSPKH RDAPWFLHSA RLVSMAGHSV LLHGHVGEGD NGGKLELAAR ACGIPLCHSL
SEAMEATSSQ RIAYLPIGGL SPQFQSLLGL HGILEMRLPL NTVVHLLNPL RAKSTMIGVA
RPSYQELHRD TARLLSVENL AILGNTRDFA QFTPFRTTRI FGLSKGRDVE WLIPARETPP
AEMPTMFTTF EYWRAVWTGA ARDERAETII ISTAAIALML VNDMALSFEE AYARSLQLWN
DRARNLAHA
//
