ID Q7CUJ3_AGRFC Unreviewed; 299 AA.
AC Q7CUJ3;
DT 05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT 15-JAN-2008, sequence version 2.
DT 27-MAR-2024, entry version 116.
DE SubName: Full=Transcriptional regulator, LysR family {ECO:0000313|EMBL:AAK89150.2};
GN OrderedLocusNames=Atu4288 {ECO:0000313|EMBL:AAK89150.2};
OS Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens
OS (strain C58)).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC Agrobacterium tumefaciens complex.
OX NCBI_TaxID=176299 {ECO:0000313|EMBL:AAK89150.2, ECO:0000313|Proteomes:UP000000813};
RN [1] {ECO:0000313|EMBL:AAK89150.2, ECO:0000313|Proteomes:UP000000813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970 {ECO:0000313|Proteomes:UP000000813};
RX PubMed=11743193; DOI=10.1126/science.1066804;
RA Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K.,
RA Zhou Y., Chen L., Wood G.E., Almeida N.F.Jr., Woo L., Chen Y.,
RA Paulsen I.T., Eisen J.A., Karp P.D., Bovee D.Sr., Chapman P.,
RA Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R.,
RA Li M.J., McClelland E., Palmieri A., Raymond C., Rouse G.,
RA Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y.,
RA Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S.,
RA Hendrick C., Zhao Z.Y., Dolan M., Chumley F., Tingey S.V., Tomb J.F.,
RA Gordon M.P., Olson M.V., Nester E.W.;
RT "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT C58.";
RL Science 294:2317-2323(2001).
RN [2] {ECO:0000313|EMBL:AAK89150.2, ECO:0000313|Proteomes:UP000000813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970 {ECO:0000313|Proteomes:UP000000813};
RX PubMed=11743194; DOI=10.1126/science.1066803;
RA Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B.,
RA Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K.,
RA Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M.,
RA Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C.,
RA Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
RT "Genome sequence of the plant pathogen and biotechnology agent
RT Agrobacterium tumefaciens C58.";
RL Science 294:2323-2328(2001).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; AE007870; AAK89150.2; -; Genomic_DNA.
DR RefSeq; NP_356365.2; NC_003063.2.
DR RefSeq; WP_010973716.1; NC_003063.2.
DR AlphaFoldDB; Q7CUJ3; -.
DR STRING; 176299.Atu4288; -.
DR EnsemblBacteria; AAK89150; AAK89150; Atu4288.
DR KEGG; atu:Atu4288; -.
DR PATRIC; fig|176299.10.peg.4097; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_16_1_5; -.
DR OrthoDB; 8300238at2; -.
DR PhylomeDB; Q7CUJ3; -.
DR BioCyc; AGRO:ATU4288-MONOMER; -.
DR Proteomes; UP000000813; Chromosome linear.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd08422; PBP2_CrgA_like; 1.
DR Gene3D; 3.40.190.290; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30537; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR PANTHER; PTHR30537:SF58; HTH-TYPE TRANSCRIPTIONAL REGULATOR PERR; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000813}.
FT DOMAIN 12..63
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 299 AA; 33281 MW; 0BBF22FEB2A88C39 CRC64;
MGRRFDHLGD VEAFIIVAEK GSMTEAAVAL ATTASVLSRA ITRLETRLGA QLMRRTTRRL
NLTDEGRAYL EQARAAFSMI DDAERAIQGP TGASLTGHVR ISVPTTYGHH RLPAMLERFM
QAYPEVQIEL SITNRNVDLV AEGYDLAIRL GPLPDSGLVA RKLEDASLRL VAAPHYLERA
GMPQDVEDLA EHQCLPFVMP STGRCAPWLF HVDGRDLDWT PPGRIQVFDD VLGVVSLAES
GLGICQIYDF IIRDRVKEGR LVEVLDHAQG RFRPFSLIFA PHRRLSAATR TLIDFLVEK
//