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Database: UniProt
Entry: Q7DJJ2
LinkDB: Q7DJJ2
Original site: Q7DJJ2 
ID   Q7DJJ2_ECOLX            Unreviewed;        89 AA.
AC   Q7DJJ2;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   10-FEB-2021, entry version 131.
DE   SubName: Full=Shiga toxin 2 B subunit {ECO:0000313|EMBL:ABR09965.1};
DE   SubName: Full=Shiga toxin 2 subunit B {ECO:0000313|EMBL:ABB52779.1};
DE   SubName: Full=Shiga toxin 2, subunit B {ECO:0000313|EMBL:CCC15126.1};
DE   SubName: Full=Shiga toxin 2B {ECO:0000313|EMBL:CCA61210.1};
DE   SubName: Full=Shiga toxin 2v subunit A {ECO:0000313|EMBL:CAX45735.1};
DE   SubName: Full=Shiga toxin Stx2 subunit B {ECO:0000313|EMBL:EAA1898421.1};
DE   SubName: Full=Stx2 holotoxin B subunit {ECO:0000313|EMBL:AIZ66855.1};
DE   SubName: Full=Stx2 holotoxin subunit B {ECO:0000313|EMBL:AJW83237.1};
DE   SubName: Full=Stx2B {ECO:0000313|EMBL:AAZ73246.1};
DE   SubName: Full=Stx2B protein {ECO:0000313|EMBL:CAC05527.1};
GN   Name=stxII {ECO:0000313|EMBL:BAA88601.1};
GN   Synonyms=stx2B {ECO:0000313|EMBL:ACU32683.1}, stx2b
GN   {ECO:0000313|EMBL:EAA1898421.1}, stx2B_2
GN   {ECO:0000313|EMBL:GDT27350.1}, stx2dB {ECO:0000313|EMBL:ADV16384.1},
GN   stx2vB {ECO:0000313|EMBL:CAX45705.1}, stxB2
GN   {ECO:0000313|EMBL:ABB52779.1}, vtx2B {ECO:0000313|EMBL:ACB37356.1};
GN   ORFNames=BvCmsHHP019_02074 {ECO:0000313|EMBL:GCP96878.1},
GN   BvCmsNSP072_02053 {ECO:0000313|EMBL:GDQ36310.1}, BvCmsOUP014_04264
GN   {ECO:0000313|EMBL:GDT27350.1}, C9Z37_23105
GN   {ECO:0000313|EMBL:TJR69705.1}, C9Z78_24425
GN   {ECO:0000313|EMBL:TJP58453.1}, D6004_26885
GN   {ECO:0000313|EMBL:EAB7438944.1}, D7K33_26370
GN   {ECO:0000313|EMBL:EAB0501212.1}, D9X77_26970
GN   {ECO:0000313|EMBL:EAC0109158.1}, DAH30_25515
GN   {ECO:0000313|EMBL:TGF86150.1}, DM155_24460
GN   {ECO:0000313|EMBL:EAA1898421.1}, DNR35_15450
GN   {ECO:0000313|EMBL:EAA2528439.1}, EBM08_12130
GN   {ECO:0000313|EMBL:EAC0708029.1}, F7F11_25580
GN   {ECO:0000313|EMBL:KAB0121443.1}, HW43_14770
GN   {ECO:0000313|EMBL:AIZ87678.1}, HZT35_28895
GN   {ECO:0000313|EMBL:QMT90508.1}, UN91_26180
GN   {ECO:0000313|EMBL:KJW44489.1};
OS   Escherichia coli.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562 {ECO:0000313|EMBL:BAA88601.1};
RN   [1] {ECO:0000313|EMBL:CAA85781.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Serotype O48:H21 strain 94C {ECO:0000313|EMBL:CAA85781.1};
RX   PubMed=7790056;
RA   Paton A.W., Bourne A.J., Manning P.A., Paton J.C.;
RT   "Comparative toxicity and virulence of Escherichia coli clones expressing
RT   variant and chimeric Shiga-like toxin type II operons.";
RL   Infect. Immun. 63:2450-2458(1995).
RN   [2] {ECO:0000313|EMBL:BAA88601.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NIID-9 {ECO:0000313|EMBL:BAA88601.1};
RX   PubMed=10746172;
RA   Miyahara M., Konuma H.;
RT   "Escherichia coli O157 strains which caused Japanese outbreaks have
RT   residues of bacteriophage sequences.";
RL   Biol. Pharm. Bull. 22:1372-1375(1999).
RN   [3] {ECO:0000313|EMBL:CAC05527.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=1448/97 {ECO:0000313|EMBL:CAC05527.1}, 3985/96
RC   {ECO:0000313|EMBL:CAC05550.1}, and Ed-147
RC   {ECO:0000313|EMBL:CAC05546.1};
RX   PubMed=10948097; DOI=10.1128/IAI.68.9.4856-4864.2000;
RA   Unkmeir A., Schmidt H.;
RT   "Structural analysis of phage-borne stx genes and their flanking sequences
RT   in shiga toxin-producing Escherichia coli and Shigella dysenteriae type 1
RT   strains.";
RL   Infect. Immun. 68:4856-4864(2000).
RN   [4] {ECO:0000313|EMBL:AAS07597.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=EBC217 {ECO:0000313|EMBL:AAS07601.1};
RX   PubMed=15466582; DOI=10.1128/AEM.70.10.6309-6314.2004;
RA   De Baets L., Van der Taelen I., De Filette M., Pierard D., Allison L.,
RA   De Greve H., Hernalsteens J.-P., Imberechts H.;
RT   "Genetic typing of shiga toxin 2 variants of Escherichia coli by PCR-
RT   restriction fragment length polymorphism analysis.";
RL   Appl. Environ. Microbiol. 70:6309-6314(2004).
RN   [5] {ECO:0000313|EMBL:ABB52779.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=1/03 {ECO:0000313|EMBL:ABB52783.1}, 164/01
RC   {ECO:0000313|EMBL:ABB52779.1}, and 258/98
RC   {ECO:0000313|EMBL:ABB52787.1};
RX   PubMed=16517637; DOI=10.1128/AEM.72.3.1900-1909.2006;
RA   Bielaszewska M., Prager R., Zhang W., Friedrich A.W., Mellmann A.,
RA   Tschape H., Karch H.;
RT   "Chromosomal dynamism in progeny of outbreak-related sorbitol-fermenting
RT   enterohemorrhagic Escherichia coli O157:NM.";
RL   Appl. Environ. Microbiol. 72:1900-1909(2006).
RN   [6] {ECO:0000313|EMBL:AAZ73246.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=02-6737 {ECO:0000313|EMBL:AAZ73246.1};
RX   PubMed=16455898; DOI=10.1128/JCM.44.2.449-458.2006;
RA   Gilmour M.W., Tracz D.M., Andrysiak A.K., Clark C.G., Tyler S.,
RA   Severini A., Ng L.-K.;
RT   "Use of the espZ gene encoded in the locus of enterocyte effacement for
RT   molecular typing of shiga toxin-producing Escherichia coli.";
RL   J. Clin. Microbiol. 44:449-458(2006).
RN   [7] {ECO:0000313|EMBL:ABR09965.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=B2F1 {ECO:0000313|EMBL:ABR09965.1};
RX   PubMed=18053224; DOI=10.1186/1471-2180-7-109;
RA   Lee J.E., Reed J., Shields M.S., Spiegel K.M., Farrell L.D., Sheridan P.P.;
RT   "Phylogenetic analysis of Shiga toxin 1 and Shiga toxin 2 genes associated
RT   with disease outbreaks.";
RL   BMC Microbiol. 7:109-109(2007).
RN   [8] {ECO:0000313|EMBL:ACB37356.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=H8432 {ECO:0000313|EMBL:ACB37358.1}, H8478
RC   {ECO:0000313|EMBL:ACB37364.1}, H8489 {ECO:0000313|EMBL:ACB37360.1},
RC   H8757 {ECO:0000313|EMBL:ACB37362.1}, and H8824
RC   {ECO:0000313|EMBL:ACB37356.1};
RX   PubMed=18852247; DOI=10.1128/IAI.01180-08;
RA   Rosser T., Dransfield T., Allison L., Hanson M., Holden N., Evans J.,
RA   Naylor S., La Ragione R., Low J.C., Gally D.L.;
RT   "Pathogenic potential of emergent sorbitol-fermenting Escherichia coli
RT   O157:NM.";
RL   Infect. Immun. 76:5598-5607(2008).
RN   [9] {ECO:0000313|EMBL:CAX45705.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=TS02/07 {ECO:0000313|EMBL:CAX45705.1}, TS05/07
RC   {ECO:0000313|EMBL:CAX45711.1}, TS07/07 {ECO:0000313|EMBL:CAX45749.1},
RC   TS17/08 {ECO:0000313|EMBL:CAX45729.1}, TS18/08
RC   {ECO:0000313|EMBL:CAX45731.1}, TS19/08 {ECO:0000313|EMBL:CAX45733.1},
RC   TS20/08 {ECO:0000313|EMBL:CAX45735.1}, TS24/08
RC   {ECO:0000313|EMBL:CAX45743.1}, and TS26/08
RC   {ECO:0000313|EMBL:CAX45745.1};
RA   Slanec T., Fruth A., Creuzburg K., Schmidt H.;
RT   "Molecular Analysis of Virulence Profiles and Shiga Toxin Genes in Food-
RT   Borne Shiga Toxin-Producing Escherichia coli.";
RL   Appl. Environ. Microbiol. -:0-0(2009).
RN   [10] {ECO:0000313|EMBL:ACD92979.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=WUS-01/27/017-1 {ECO:0000313|EMBL:ACD92979.1};
RX   PubMed=19734327; DOI=10.1128/AEM.00605-09;
RA   Geue L., Klare S., Schnick C., Mintel B., Meyer K., Conraths F.J.;
RT   "Analysis of the clonal relationship of serotype O26:H11 enterohemorrhagic
RT   Escherichia coli isolates from cattle.";
RL   Appl. Environ. Microbiol. 75:6947-6953(2009).
RN   [11] {ECO:0000313|EMBL:ACU32683.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=23765 {ECO:0000313|EMBL:ACU32685.1}, N11354
RC   {ECO:0000313|EMBL:ACU32699.1}, N11355 {ECO:0000313|EMBL:ACU32701.1},
RC   N22813 {ECO:0000313|EMBL:ACU32683.1}, N2688
RC   {ECO:0000313|EMBL:ACU32687.1}, and N5578
RC   {ECO:0000313|EMBL:ACU32697.1};
RX   PubMed=20080990; DOI=10.1128/AEM.01968-09;
RA   Xia X., Meng J., McDermott P.F., Ayers S., Blickenstaff K., Tran T.T.,
RA   Abbott J., Zheng J., Zhao S.;
RT   "Presence and characterization of shiga toxin-producing Escherichia coli
RT   and other potentially diarrheagenic E. coli strains in retail meats.";
RL   Appl. Environ. Microbiol. 76:1709-1717(2010).
RN   [12] {ECO:0000313|EMBL:ADV16384.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=3024-94 {ECO:0000313|EMBL:ADV16384.1};
RX   PubMed=21199911; DOI=10.1128/IAI.01182-10;
RA   Fuller C.A., Pellino C.A., Flagler M.J., Strasser J.E., Weiss A.A.;
RT   "Shiga toxin subtypes display dramatic differences in potency.";
RL   Infect. Immun. 79:1329-1337(2011).
RN   [13] {ECO:0000313|EMBL:CCA62488.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CB12503 {ECO:0000313|EMBL:CCA62488.1};
RA   Beutin L., Miko A.;
RT   "Characterization of stx2 variants present in shiga toxin producing E.
RT   coli.";
RL   Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
RN   [14] {ECO:0000313|EMBL:CCC15126.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=1106-4002 {ECO:0000313|EMBL:CCC15126.1}, and 1109-0113
RC   {ECO:0000313|EMBL:CCC15131.1};
RX   PubMed=22268961; DOI=10.1111/j.1574-6968.2012.02505.x;
RA   Haugum K., Lindstedt B.A., Lobersli I., Kapperud G., Brandal L.T.;
RT   "Identification of the anti-terminator q(O111:H) (-) gene in Norwegian
RT   sorbitol-fermenting Escherichia coli O157:NM.";
RL   FEMS Microbiol. Lett. 329:102-110(2012).
RN   [15] {ECO:0000313|EMBL:CCA61210.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CB11017 {ECO:0000313|EMBL:CCA61210.1}, CB12249
RC   {ECO:0000313|EMBL:CCA61212.1}, CB12260 {ECO:0000313|EMBL:CCA61216.1},
RC   and CB12275 {ECO:0000313|EMBL:CCA61220.1};
RX   PubMed=24987616; DOI=10.3389/fcimb.2014.00078;
RA   Miko A., Rivas M., Bentancor A., Delannoy S., Fach P., Beutin L.;
RT   "Emerging types of Shiga toxin-producing E. coli (STEC) O178 present in
RT   cattle, deer, and humans from Argentina and Germany.";
RL   Front. Cell. Infect. Microbiol. 4:78-78(2014).
RN   [16] {ECO:0000213|PDB:4M1U}
RP   X-RAY CRYSTALLOGRAPHY (1.56 ANGSTROMS) OF 20-89, AND DISULFIDE BONDS.
RX   PubMed=24225957; DOI=10.1074/jbc.m113.518886;
RA   Jacobson J.M., Yin J., Kitov P.I., Mulvey G., Griener T.P., James M.N.,
RA   Armstrong G., Bundle D.R.;
RT   "The crystal structure of shiga toxin type 2 with bound disaccharide guides
RT   the design of a heterobifunctional toxin inhibitor.";
RL   J. Biol. Chem. 289:885-894(2014).
RN   [17] {ECO:0000313|EMBL:AIZ66855.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=SWUN4280 {ECO:0000313|EMBL:AIZ66855.1};
RA   Liu F., Tong J., Tang C.;
RT   "Phylogenetic diversity and similarity of active sites of Shigatoxin (Stx)
RT   in Shiga toxin-producing Escherichia coli (STEC) isolates from Yak Meat.";
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN   [18] {ECO:0000313|EMBL:AJW83237.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=SWUN4086 {ECO:0000313|EMBL:AJW83237.1};
RA   Liu F., Tong J., Tang C.;
RT   "Phylogenetic diversity and similarity of active sites of shiga toxin (Stx)
RT   in shiga toxin-producing Escherichia coli (STEC) isolates from yak.";
RL   Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
RN   [19] {ECO:0000313|EMBL:AIZ87678.1, ECO:0000313|Proteomes:UP000030783}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=94-3024 {ECO:0000313|EMBL:AIZ87678.1,
RC   ECO:0000313|Proteomes:UP000030783};
RX   PubMed=25887577; DOI=10.1186/s12866-015-0413-9;
RA   Yan X., Fratamico P.M., Bono J.L., Baranzoni G.M., Chen C.Y.;
RT   "Genome sequencing and comparative genomics provides insights on the
RT   evolutionary dynamics and pathogenic potential of different H-serotypes of
RT   Shiga toxin-producing Escherichia coli O104.";
RL   BMC Microbiol. 15:83-83(2015).
RN   [20] {ECO:0000313|EMBL:KJW44489.1, ECO:0000313|Proteomes:UP000033371}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=St. Olav173 {ECO:0000313|EMBL:KJW44489.1,
RC   ECO:0000313|Proteomes:UP000033371};
RA   Gabrielsen C., Afset J.E., Drablos F.;
RT   "Genome sequences of 11 non-O157 Shiga Toxin-Producing Escherichia coli
RT   strains.";
RL   Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
RN   [21] {ECO:0000313|EMBL:AIZ87678.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=94-3024 {ECO:0000313|EMBL:AIZ87678.1};
RA   Yan X., Fratamico P.M., Bono J.L., Baranzoni G., Tebbs R., O'Connell C.;
RT   "Escherichia coli O104:H21 Montana milk outbreak str. 93-3024.";
RL   Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
RN   [22] {ECO:0000313|EMBL:ABB60237.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=258/98 {ECO:0000313|EMBL:ABB60237.1};
RA   Song W.-J., Kurnit D.M.;
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
RN   [23] {ECO:0000313|EMBL:TGF86150.1, ECO:0000313|Proteomes:UP000297660}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DEC 023 {ECO:0000313|EMBL:TGF86150.1,
RC   ECO:0000313|Proteomes:UP000297660};
RA   Baranzoni G.M., Fratamico P.M., Kim G.-H., Funk J.A., Manning S.D.,
RA   Bosilevac J.M.;
RT   "Whole genome sequences of Shiga Toxin-producing Escherichia coli isolated
RT   from swine and other sources.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [24] {ECO:0000313|Proteomes:UP000299254, ECO:0000313|Proteomes:UP000304338, ECO:0000313|Proteomes:UP000304738}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HH-P019 {ECO:0000313|EMBL:GCP96878.1,
RC   ECO:0000313|Proteomes:UP000304338}, NS-P072
RC   {ECO:0000313|EMBL:GDQ36310.1, ECO:0000313|Proteomes:UP000299254}, and
RC   OU-P014 {ECO:0000313|EMBL:GDT27350.1,
RC   ECO:0000313|Proteomes:UP000304738};
RA   Arimizu Y., Ogura Y.;
RT   "Large scale genomics of bovine and human commensal E. coli to reveal the
RT   emerging process of EHEC.";
RL   Submitted (APR-2018) to the EMBL/GenBank/DDBJ databases.
RN   [25] {ECO:0000313|EMBL:ABB60213.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=258/98 {ECO:0000313|EMBL:ABB60213.1};
RA   Quirk P.G., Krulwich T.A.;
RL   Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
RN   [26] {ECO:0000313|EMBL:EAB0501212.1, ECO:0000313|Proteomes:UP000365631}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PNUSAE018290 {ECO:0000313|EMBL:EAB0501212.1,
RC   ECO:0000313|Proteomes:UP000365631};
RG   PulseNet: The National Subtyping Network for Foodborne Disease Surveillance;
RA   Tarr C.L., Trees E., Katz L.S., Carleton-Romer H.A., Stroika S.,
RA   Kucerova Z., Roache K.F., Sabol A.L., Besser J., Gerner-Smidt P.;
RL   Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
RN   [27] {ECO:0000313|EMBL:EAC0109158.1, ECO:0000313|Proteomes:UP000373593, ECO:0000313|Proteomes:UP000373983}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=410823 {ECO:0000313|EMBL:EAA1898421.1,
RC   ECO:0000313|Proteomes:UP000404067}, 428113
RC   {ECO:0000313|EMBL:EAA2528439.1, ECO:0000313|Proteomes:UP000401045},
RC   608445 {ECO:0000313|EMBL:EAB7438944.1,
RC   ECO:0000313|Proteomes:UP000370801}, 619952
RC   {ECO:0000313|EMBL:EAC0109158.1, ECO:0000313|Proteomes:UP000373593},
RC   and 624508 {ECO:0000313|EMBL:EAC0708029.1,
RC   ECO:0000313|Proteomes:UP000373983};
RA   Ashton P.M., Dallman T., Nair S., De Pinna E., Peters T., Grant K.;
RL   Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
RN   [28] {ECO:0000313|EMBL:TJP58453.1, ECO:0000313|Proteomes:UP000305248, ECO:0000313|Proteomes:UP000305571}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FWSEC0087 {ECO:0000313|EMBL:TJR69705.1,
RC   ECO:0000313|Proteomes:UP000305571}, and FWSEC0128
RC   {ECO:0000313|EMBL:TJP58453.1, ECO:0000313|Proteomes:UP000305248};
RA   Tyson S., Peterson C.-L., Olson A., Tyler S., Cabral J., Lynch T., Knox N.,
RA   Van Domselaar G., Graham M.;
RT   "Food and Water Safety Consortium.";
RL   Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
RN   [29] {ECO:0000313|EMBL:KAB0121443.1, ECO:0000313|Proteomes:UP000327073}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=STEC_170836 {ECO:0000313|EMBL:KAB0121443.1,
RC   ECO:0000313|Proteomes:UP000327073};
RA   Abdalhamid B., Mccutchen E.L., Bouska A.C., Hinrichs S.H., Iwen P.C.;
RT   "Whole Genome Sequencing of Shiga-Toxin Escherichia coli Strains from
RT   Nebraska.";
RL   Submitted (MAR-2019) to the EMBL/GenBank/DDBJ databases.
RN   [30] {ECO:0000213|PDB:6X6H}
RP   X-RAY CRYSTALLOGRAPHY (1.88 ANGSTROMS) OF 20-89, AND DISULFIDE BONDS.
RX   PubMed=32878986; DOI=10.1074/jbc.ac120.015070;
RA   Rudolph M.J., Davis S.A., Tumer N.E., Li X.P.;
RT   "Structural basis for the interaction of Shiga toxin 2a with a C-terminal
RT   peptide of ribosomal P stalk proteins.";
RL   J. Biol. Chem. 0:0-0(2020).
RN   [31] {ECO:0000313|Proteomes:UP000514491}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MBT-5 {ECO:0000313|Proteomes:UP000514491};
RA   Fiedler G., Kabisch J., Brinks E., Sprotte S., Boehnlein C.,
RA   Franz C.M.A.P.;
RT   "Complete genome of a Shiga toxin-producing Escherichia coli O26:H11 strain
RT   (ST21) and two draft genomes of Listeria monocytogenes strains (CC1, CC59)
RT   isolated from fresh produce.";
RL   Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases.
RN   [32] {ECO:0000313|EMBL:QMT90508.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=MBT-5 {ECO:0000313|EMBL:QMT90508.1};
RA   Fiedler G., Kabisch J., Brinks E., Sprotte S., Boehnlein C.,
RA   Franz C.M.A.P.;
RT   "Complete genome of a Shiga toxin-producing Escherichia coli O26:H11 strain
RT   (ST21) and two draft genomes of Listeria monocytogenes strains (CC1, CC59)
RT   isolated from fresh produce.";
RL   Submitted (SEP-2020) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The B subunit is responsible for the binding of the holotoxin
CC       to specific receptors on the target cell surface, such as
CC       globotriaosylceramide (Gb3) in human intestinal microvilli.
CC       {ECO:0000256|ARBA:ARBA00003218}.
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DR   EMBL; AY443052; AAS07597.1; -; Genomic_DNA.
DR   EMBL; AY443054; AAS07601.1; -; Genomic_DNA.
DR   EMBL; DQ143181; AAZ73246.1; -; Genomic_DNA.
DR   EMBL; DQ231582; ABB52779.1; -; Genomic_DNA.
DR   EMBL; DQ231583; ABB52781.1; -; Genomic_DNA.
DR   EMBL; DQ231584; ABB52783.1; -; Genomic_DNA.
DR   EMBL; DQ231585; ABB52785.1; -; Genomic_DNA.
DR   EMBL; DQ231586; ABB52787.1; -; Genomic_DNA.
DR   EMBL; DQ231587; ABB52789.1; -; Genomic_DNA.
DR   EMBL; DQ231588; ABB52791.1; -; Genomic_DNA.
DR   EMBL; DQ231591; ABB60213.1; -; Genomic_DNA.
DR   EMBL; DQ231595; ABB60237.1; -; Genomic_DNA.
DR   EMBL; EF441620; ABR09965.1; -; Genomic_DNA.
DR   EMBL; EU526760; ACB37356.1; -; Genomic_DNA.
DR   EMBL; EU526761; ACB37358.1; -; Genomic_DNA.
DR   EMBL; EU526762; ACB37360.1; -; Genomic_DNA.
DR   EMBL; EU526763; ACB37362.1; -; Genomic_DNA.
DR   EMBL; EU526764; ACB37364.1; -; Genomic_DNA.
DR   EMBL; EU700491; ACD92979.1; -; Genomic_DNA.
DR   EMBL; GQ429161; ACU32683.1; -; Genomic_DNA.
DR   EMBL; GQ429162; ACU32685.1; -; Genomic_DNA.
DR   EMBL; GQ429163; ACU32687.1; -; Genomic_DNA.
DR   EMBL; GQ429168; ACU32697.1; -; Genomic_DNA.
DR   EMBL; GQ429169; ACU32699.1; -; Genomic_DNA.
DR   EMBL; GQ429170; ACU32701.1; -; Genomic_DNA.
DR   EMBL; HQ585062; ADV16384.1; -; Genomic_DNA.
DR   EMBL; KM516094; AIZ66855.1; -; Genomic_DNA.
DR   EMBL; CP009106; AIZ87678.1; -; Genomic_DNA.
DR   EMBL; KP120723; AJW83237.1; -; Genomic_DNA.
DR   EMBL; AB028899; BAA88601.1; -; Genomic_DNA.
DR   EMBL; Z37725; CAA85781.1; -; Genomic_DNA.
DR   EMBL; AJ250954; CAC05527.1; -; Genomic_DNA.
DR   EMBL; AJ251483; CAC05546.1; -; Genomic_DNA.
DR   EMBL; AJ251520; CAC05550.1; -; Genomic_DNA.
DR   EMBL; FM998839; CAX45705.1; -; Genomic_DNA.
DR   EMBL; FM998842; CAX45711.1; -; Genomic_DNA.
DR   EMBL; FM998851; CAX45729.1; -; Genomic_DNA.
DR   EMBL; FM998852; CAX45731.1; -; Genomic_DNA.
DR   EMBL; FM998853; CAX45733.1; -; Genomic_DNA.
DR   EMBL; FM998854; CAX45735.1; -; Genomic_DNA.
DR   EMBL; FM998858; CAX45743.1; -; Genomic_DNA.
DR   EMBL; FM998859; CAX45745.1; -; Genomic_DNA.
DR   EMBL; FM998861; CAX45749.1; -; Genomic_DNA.
DR   EMBL; FR846369; CCA61210.1; -; Genomic_DNA.
DR   EMBL; FR846370; CCA61212.1; -; Genomic_DNA.
DR   EMBL; FR846372; CCA61216.1; -; Genomic_DNA.
DR   EMBL; FR846374; CCA61220.1; -; Genomic_DNA.
DR   EMBL; FR850031; CCA62488.1; -; Genomic_DNA.
DR   EMBL; FR874039; CCC15126.1; -; Genomic_DNA.
DR   EMBL; FR874040; CCC15131.1; -; Genomic_DNA.
DR   EMBL; AAAASG010000078; EAA1898421.1; -; Genomic_DNA.
DR   EMBL; AAAAXI010000022; EAA2528439.1; -; Genomic_DNA.
DR   EMBL; AAADKR010000081; EAB0501212.1; -; Genomic_DNA.
DR   EMBL; AAAFQE010000129; EAB7438944.1; -; Genomic_DNA.
DR   EMBL; AAAGMU010000215; EAC0109158.1; -; Genomic_DNA.
DR   EMBL; AAAGRT010000024; EAC0708029.1; -; Genomic_DNA.
DR   EMBL; BFKR01000277; GCP96878.1; -; Genomic_DNA.
DR   EMBL; BGER01000064; GDQ36310.1; -; Genomic_DNA.
DR   EMBL; BGFY01000099; GDT27350.1; -; Genomic_DNA.
DR   EMBL; VZEL01000062; KAB0121443.1; -; Genomic_DNA.
DR   EMBL; JZDZ01000124; KJW44489.1; -; Genomic_DNA.
DR   EMBL; CP058682; QMT90508.1; -; Genomic_DNA.
DR   EMBL; QAFB01000047; TGF86150.1; -; Genomic_DNA.
DR   EMBL; RRGT01000052; TJP58453.1; -; Genomic_DNA.
DR   EMBL; RRFG01000055; TJR69705.1; -; Genomic_DNA.
DR   RefSeq; WP_000738072.1; NZ_WTLO01000039.1.
DR   PDB; 4M1U; X-ray; 1.56 A; B/C/D/E/F=20-89.
DR   PDB; 6X6H; X-ray; 1.88 A; B/C/D/E/F=20-89.
DR   PDBsum; 4M1U; -.
DR   EnsemblBacteria; AIZ82002; AIZ82002; HW42_08855.
DR   EnsemblBacteria; KJW44489; KJW44489; UN91_26180.
DR   EnsemblBacteria; KNY78905; KNY78905; AGA26_00045.
DR   PATRIC; fig|562.7005.peg.5237; -.
DR   Proteomes; UP000030783; Chromosome.
DR   Proteomes; UP000033371; Unassembled WGS sequence.
DR   Proteomes; UP000297660; Unassembled WGS sequence.
DR   Proteomes; UP000299254; Unassembled WGS sequence.
DR   Proteomes; UP000304338; Unassembled WGS sequence.
DR   Proteomes; UP000304738; Unassembled WGS sequence.
DR   Proteomes; UP000305248; Unassembled WGS sequence.
DR   Proteomes; UP000305571; Unassembled WGS sequence.
DR   Proteomes; UP000327073; Unassembled WGS sequence.
DR   Proteomes; UP000365631; Unassembled WGS sequence.
DR   Proteomes; UP000370801; Unassembled WGS sequence.
DR   Proteomes; UP000373593; Unassembled WGS sequence.
DR   Proteomes; UP000373983; Unassembled WGS sequence.
DR   Proteomes; UP000401045; Unassembled WGS sequence.
DR   Proteomes; UP000404067; Unassembled WGS sequence.
DR   Proteomes; UP000514491; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0019836; P:hemolysis by symbiont of host erythrocytes; IEA:InterPro.
DR   GO; GO:0009405; P:pathogenesis; IEA:InterPro.
DR   InterPro; IPR008992; Enterotoxin.
DR   InterPro; IPR003189; SLT_beta.
DR   Pfam; PF02258; SLT_beta; 1.
DR   SUPFAM; SSF50203; SSF50203; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0000213|PDB:4M1U, ECO:0000213|PDB:6X6H};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..89
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5015098708"
FT   DISULFID        22..75
FT                   /evidence="ECO:0000213|PDB:4M1U, ECO:0000213|PDB:6X6H"
SQ   SEQUENCE   89 AA;  9902 MW;  C1198B5B6E5C0ACB CRC64;
     MKKMFMAVLF ALVSVNAMAA DCAKGKIEFS KYNEDDTFTV KVDGKEYWTS RWNLQPLLQS
     AQLTGMTVTI KSSTCESGSG FAEVQFNND
//
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