ID Q7M8P0_WOLSU Unreviewed; 530 AA.
AC Q7M8P0;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2003, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=INTEGRAL MEMBRANE PROTEIN-Small-conductance mechanosensitive channel {ECO:0000313|EMBL:CAE10564.1};
GN OrderedLocusNames=WS1516 {ECO:0000313|EMBL:CAE10564.1};
OS Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC
OS 11488 / FDC 602W) (Vibrio succinogenes).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Wolinella.
OX NCBI_TaxID=273121 {ECO:0000313|Proteomes:UP000000422};
RN [1] {ECO:0000313|EMBL:CAE10564.1, ECO:0000313|Proteomes:UP000000422}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29543 / DSM 1740 / CCUG 13145 / JCM 31913 / LMG 7466 /
RC NCTC 11488 / FDC 602W {ECO:0000313|Proteomes:UP000000422};
RX PubMed=14500908; DOI=10.1073/pnas.1932838100;
RA Baar C., Eppinger M., Raddatz G., Simon JM., Lanz C., Klimmek O.,
RA Nandakumar R., Gross R., Rosinus A., Keller H., Jagtap P., Linke B.,
RA Meyer F., Lederer H., Schuster S.C.;
RT "Complete genome sequence and analysis of Wolinella succinogenes.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:11690-11695(2003).
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DR EMBL; BX571661; CAE10564.1; -; Genomic_DNA.
DR RefSeq; WP_011139348.1; NC_005090.1.
DR AlphaFoldDB; Q7M8P0; -.
DR STRING; 273121.WS1516; -.
DR KEGG; wsu:WS1516; -.
DR eggNOG; COG0668; Bacteria.
DR HOGENOM; CLU_537133_0_0_7; -.
DR Proteomes; UP000000422; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 2.30.30.60; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR PANTHER; PTHR30566:SF5; MECHANOSENSITIVE ION CHANNEL PROTEIN 1, MITOCHONDRIAL-RELATED; 1.
DR PANTHER; PTHR30566; YNAI-RELATED MECHANOSENSITIVE ION CHANNEL; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000422};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..530
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004288439"
FT TRANSMEM 232..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 313..395
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT COILED 82..234
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 530 AA; 60796 MW; D5B116697E61F3D4 CRC64;
MRLIFSLIFL FLSTLALHAE EVGTPLKADQ MRENLKEINR FLEDSNNIWM KKYANFRAYR
NIVAEIESVK ERLSLFQKRS KTLANQNEVA TLERRLETLE KQRELMQEYK DNPFKELIQP
LERGEVASVT NPILIIQAFS HIRQSKQELE TLERNFESLK RVVESLKTKE ALLYELVVLE
GIEEEVMEYK ETQNALGELE STQNIFSTTL GLYRKKVEEQ TQRLTEQIKA QAVKAVYIGV
AVLLLFVLAL LMKMGIKKYI HDNERIYTAN KIINFANLTL IIFILLFAYL ENVTYLVTVL
GFASAGLAIA MKDLFMSVLG WIVIVIGGAV HVGDRIRVTK DGSTYIGDVL DISILRITMH
EGITLTTYME NRRAGRIIFV PNNYIFTTMF ANYTHSGMKT VWDGIDFTIT FESNHRKMVQ
IALDITKKYA KGYTEITRKQ LNRLRDRYSL RNTNVEPRAF TMLEPNGIRI SIWYQTNAYA
ALTLRSTISG EIVDALLAEP DIEIAYPTTT VRAPKEPLPP SDGAIPPVHL
//
