ID Q7M9B1_WOLSU Unreviewed; 749 AA.
AC Q7M9B1;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2003, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=FLBA {ECO:0000313|EMBL:CAE10152.1};
GN Synonyms=flhA {ECO:0000256|RuleBase:RU364093};
GN OrderedLocusNames=WS1053 {ECO:0000313|EMBL:CAE10152.1};
OS Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC
OS 11488 / FDC 602W) (Vibrio succinogenes).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Wolinella.
OX NCBI_TaxID=273121 {ECO:0000313|Proteomes:UP000000422};
RN [1] {ECO:0000313|EMBL:CAE10152.1, ECO:0000313|Proteomes:UP000000422}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29543 / DSM 1740 / CCUG 13145 / JCM 31913 / LMG 7466 /
RC NCTC 11488 / FDC 602W {ECO:0000313|Proteomes:UP000000422};
RX PubMed=14500908; DOI=10.1073/pnas.1932838100;
RA Baar C., Eppinger M., Raddatz G., Simon JM., Lanz C., Klimmek O.,
RA Nandakumar R., Gross R., Rosinus A., Keller H., Jagtap P., Linke B.,
RA Meyer F., Lederer H., Schuster S.C.;
RT "Complete genome sequence and analysis of Wolinella succinogenes.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:11690-11695(2003).
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
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DR EMBL; BX571659; CAE10152.1; -; Genomic_DNA.
DR RefSeq; WP_011138945.1; NC_005090.1.
DR AlphaFoldDB; Q7M9B1; -.
DR STRING; 273121.WS1053; -.
DR KEGG; wsu:WS1053; -.
DR eggNOG; COG1298; Bacteria.
DR HOGENOM; CLU_015346_3_0_7; -.
DR Proteomes; UP000000422; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:CAE10152.1};
KW Cilium {ECO:0000313|EMBL:CAE10152.1};
KW Flagellum {ECO:0000313|EMBL:CAE10152.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Reference proteome {ECO:0000313|Proteomes:UP000000422};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 26..44
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 50..69
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 121..144
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 213..235
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 255..273
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 294..312
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT REGION 358..398
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 749 AA; 81375 MW; 9E88416D5AE17F49 CRC64;
MAKTKEKTLA QRALPFLKAI SESKDLTVVV FIISILAIII VPLPSALLDF FLTISIAVSV
LIILISLYIA KPTDFTAFPT LLLIVTLFRL ALNVSTTRMI LSEGHNGPDA VSDIISSFGN
FVVGGNYVIG IIVFLILVII NFMVVTNGST RVAEVAARFT LDAMPGKQMA IDADMNAGLI
DEKEAKKRRE GLAQEADFYG SMDGASKFVK GDAVAGIIIT LINIIGGFLI GVFQHDLTMA
NSATTFTILT IGDGLVSQLP ALIISTATGI IVTRSSKNDE GGNFAEGIIT QLMSESKILT
IVGGILLMFA LVPGLPTLSL GFVGLLFVGM AYLIKRQEEG GAFDLLERFI NKKAGEPLAA
PLPSKKPKTA KEGAAPGEAG EGQVPATPPK KSPEEIKKQE EEALSEILKV EILELDLGYQ
LIKLADSNQG GDLLERVRGM RRKMAADYGF LMPQVRIRDN LQLPPSHYEI LLKGVAIGEG
SVLPDRFLAM NSGLVTDEIE GTPTKEPAFG LDAIWIDPRE KEEAIMRGYT VVDPATVIST
HMSELVKKYA EELITRQEVH ALMDKLAKDY PIIVEDARKS ANTGLIQQVL KALLHERIPI
KDMLTILETI ADVAPQVGGN LDVIVEQVRA RLSRVITTVF KNEDGILKLL TLSTQTEQHL
LNKVKDQQGR RQFLLSVNET NALIEGVSGE VQRVLQRGVV PVVIIVDPLL RKFLADKMEQ
FGLDVVVLSH AEIDTSAKFE VLGTITIPF
//
