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Database: UniProt
Entry: Q7MCT8_VIBVY
LinkDB: Q7MCT8_VIBVY
Original site: Q7MCT8_VIBVY 
ID   Q7MCT8_VIBVY            Unreviewed;       356 AA.
AC   Q7MCT8;
DT   15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT   15-DEC-2003, sequence version 1.
DT   08-MAY-2019, entry version 94.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   OrderedLocusNames=VVA1298 {ECO:0000313|EMBL:BAC97324.1};
OS   Vibrio vulnificus (strain YJ016).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC   Vibrionaceae; Vibrio.
OX   NCBI_TaxID=196600 {ECO:0000313|EMBL:BAC97324.1, ECO:0000313|Proteomes:UP000002675};
RN   [1] {ECO:0000313|EMBL:BAC97324.1, ECO:0000313|Proteomes:UP000002675}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJ016 {ECO:0000313|EMBL:BAC97324.1,
RC   ECO:0000313|Proteomes:UP000002675};
RX   PubMed=14656965; DOI=10.1101/gr.1295503;
RA   Chen C.Y., Wu K.M., Chang Y.C., Chang C.H., Tsai H.C., Liao T.L.,
RA   Liu Y.M., Chen H.J., Shen A.B., Li J.C., Su T.L., Shao C.P., Lee C.T.,
RA   Hor L.I., Tsai S.F.;
RT   "Comparative genome analysis of Vibrio vulnificus, a marine
RT   pathogen.";
RL   Genome Res. 13:2577-2587(2003).
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
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DR   EMBL; BA000038; BAC97324.1; -; Genomic_DNA.
DR   RefSeq; WP_011152542.1; NC_005140.1.
DR   STRING; 672.VV93_v1c42180; -.
DR   EnsemblBacteria; BAC97324; BAC97324; BAC97324.
DR   GeneID; 2622160; -.
DR   KEGG; vvy:VVA1298; -.
DR   PATRIC; fig|196600.6.peg.4446; -.
DR   HOGENOM; HOG000220501; -.
DR   KO; K01626; -.
DR   OMA; ISDLICW; -.
DR   OrthoDB; 853329at2; -.
DR   BioCyc; VVUL196600:GJ9W-4697-MONOMER; -.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000002675; Chromosome II.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002675};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002675};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156}.
FT   DOMAIN       44    337       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   356 AA;  39160 MW;  D55F8092C1AA865A CRC64;
     MPTLSKLIHS TPCGTLPSVE EIIQHASLDE ESEAFIRQRR QDITRILNGQ DPRLLVIIGP
     CSIHDPQAGL EYAQKLANIQ HQHEKQLLIV MRTYFEKPRT RAGWKGLIVD PDLDNSHDIN
     KGLRLARHFL QQVIKLGLAT ATEYLDTTTY PYISDLICWG AIGARTTESQ IHRQMASALP
     CPIGFKNGTD GNVDIAIDAI HAANSPHLIC VPGFGARTLT AISHGNPNGH IILRGGKTPN
     YTTEHVCQIS QQLEANDLNP RLIIDCSHGN SLKVAKNQLD VARNIACQLI EGEKCIAGVM
     AESFLVAGAQ KITDRPLIKG MSITDECLGW EETESILNIF AEAVNIVMTE RFSTVA
//
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