ID Q7MHT7_VIBVY Unreviewed; 408 AA.
AC Q7MHT7;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2003, sequence version 1.
DT 27-MAR-2024, entry version 114.
DE SubName: Full=Type IV pilus (Tfp) assembly protein PilC {ECO:0000313|EMBL:BAC95544.1};
GN OrderedLocusNames=VV2780 {ECO:0000313|EMBL:BAC95544.1};
OS Vibrio vulnificus (strain YJ016).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=196600 {ECO:0000313|EMBL:BAC95544.1, ECO:0000313|Proteomes:UP000002675};
RN [1] {ECO:0000313|EMBL:BAC95544.1, ECO:0000313|Proteomes:UP000002675}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YJ016 {ECO:0000313|EMBL:BAC95544.1,
RC ECO:0000313|Proteomes:UP000002675};
RX PubMed=14656965; DOI=10.1101/gr.1295503;
RA Chen C.Y., Wu K.M., Chang Y.C., Chang C.H., Tsai H.C., Liao T.L., Liu Y.M.,
RA Chen H.J., Shen A.B., Li J.C., Su T.L., Shao C.P., Lee C.T., Hor L.I.,
RA Tsai S.F.;
RT "Comparative genome analysis of Vibrio vulnificus, a marine pathogen.";
RL Genome Res. 13:2577-2587(2003).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429, ECO:0000256|RuleBase:RU003923}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004429,
CC ECO:0000256|RuleBase:RU003923}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the GSP F family.
CC {ECO:0000256|ARBA:ARBA00005745, ECO:0000256|RuleBase:RU003923}.
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DR EMBL; BA000037; BAC95544.1; -; Genomic_DNA.
DR RefSeq; WP_011151130.1; NC_005139.1.
DR AlphaFoldDB; Q7MHT7; -.
DR STRING; 672.VV93_v1c24910; -.
DR KEGG; vvy:VV2780; -.
DR PATRIC; fig|196600.6.peg.2771; -.
DR eggNOG; COG1459; Bacteria.
DR HOGENOM; CLU_035032_2_0_6; -.
DR Proteomes; UP000002675; Chromosome I.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 1.20.81.30; Type II secretion system (T2SS), domain F; 2.
DR InterPro; IPR003004; GspF/PilC.
DR InterPro; IPR001992; T2SS_GspF/T4SS_PilC_CS.
DR InterPro; IPR018076; T2SS_GspF_dom.
DR InterPro; IPR042094; T2SS_GspF_sf.
DR PANTHER; PTHR30012; GENERAL SECRETION PATHWAY PROTEIN; 1.
DR PANTHER; PTHR30012:SF7; PROTEIN TRANSPORT PROTEIN HOFC HOMOLOG; 1.
DR Pfam; PF00482; T2SSF; 2.
DR PRINTS; PR00812; BCTERIALGSPF.
DR PROSITE; PS00874; T2SP_F; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003923};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003923}.
FT TRANSMEM 169..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 380..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 74..196
FT /note="Type II secretion system protein GspF"
FT /evidence="ECO:0000259|Pfam:PF00482"
FT DOMAIN 277..399
FT /note="Type II secretion system protein GspF"
FT /evidence="ECO:0000259|Pfam:PF00482"
SQ SEQUENCE 408 AA; 45270 MW; 46513C98D2E0A052 CRC64;
MKLKTHSQIK NYQWKGINGA GKKVSGNTLA LTELEVRDKL KMQHIQIKKI KKSSVSVFTR
LSHKVKGKDI TLLTRQLSTM LTTGVPILQS LKLVADNHRK AEMKSILANV SKAVEAGTPL
SKALRSASPQ FDGIYVDLVA TGEQSGNLDQ VFERLAFYRE KNEQLRAKVI KALIYPCMVV
LVALGVSYLM LTQVIPEFRK MFTGFGAELP WFTQKVLDLS DFVQAYSSWF FITLFSAIYL
LRGLSKKSPA FRLKMSRLSL KIPVIGGVLS KAAIAKFSRT LATSFSAGIP ILTSLKTTSK
TAGNLHYQYA IEDVYRDTAA GMPMYIAMRN SLAFPELVLQ MVMIGEESGQ MDDMLNKIAT
IYEFEVDNTV DNLGKILEPL IIVFLGVVVG GLVTAMYLPI FNLMSVLG
//
