ID Q7MUV6_PORGI Unreviewed; 292 AA.
AC Q7MUV6;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2003, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE RecName: Full=Uridine phosphorylase {ECO:0000256|ARBA:ARBA00021980};
DE EC=2.4.2.3 {ECO:0000256|ARBA:ARBA00011888};
GN OrderedLocusNames=PG_1371 {ECO:0000313|EMBL:AAQ66435.1};
OS Porphyromonas gingivalis (strain ATCC BAA-308 / W83).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Porphyromonadaceae;
OC Porphyromonas.
OX NCBI_TaxID=242619 {ECO:0000313|EMBL:AAQ66435.1, ECO:0000313|Proteomes:UP000000588};
RN [1] {ECO:0000313|EMBL:AAQ66435.1, ECO:0000313|Proteomes:UP000000588}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-308 / W83 {ECO:0000313|Proteomes:UP000000588};
RX PubMed=12949112; DOI=10.1128/JB.185.18.5591-5601.2003;
RA Nelson K., Fleishmann R., DeBoy R., Paulsen I., Fouts D., Eisen J.,
RA Daugherty S., Dodson R., Durkin A., Gwinn M., Haft D., Kolonay J.,
RA Nelson W., White O., Mason T., Tallon L., Gray J., Granger D., Tettelin H.,
RA Dong H., Galvin J., Duncan M., Dewhirst F., Fraser C.;
RT "Complete genome sequence of the oral pathogenic bacterium Porphyromonas
RT gingivalis strain W83.";
RL J. Bacteriol. 185:5591-5601(2003).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=phosphate + uridine = alpha-D-ribose 1-phosphate + uracil;
CC Xref=Rhea:RHEA:24388, ChEBI:CHEBI:16704, ChEBI:CHEBI:17568,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:57720; EC=2.4.2.3;
CC Evidence={ECO:0000256|ARBA:ARBA00001020};
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DR EMBL; AE015924; AAQ66435.1; -; Genomic_DNA.
DR RefSeq; WP_005874312.1; NC_002950.2.
DR AlphaFoldDB; Q7MUV6; -.
DR STRING; 242619.PG_1371; -.
DR EnsemblBacteria; AAQ66435; AAQ66435; PG_1371.
DR GeneID; 29256364; -.
DR KEGG; pgi:PG_1371; -.
DR eggNOG; COG2820; Bacteria.
DR HOGENOM; CLU_075954_0_0_10; -.
DR Proteomes; UP000000588; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
DR CDD; cd00436; UP_TbUP-like; 1.
DR Gene3D; 3.40.50.1580; Nucleoside phosphorylase domain; 1.
DR InterPro; IPR000845; Nucleoside_phosphorylase_d.
DR InterPro; IPR035994; Nucleoside_phosphorylase_sf.
DR PANTHER; PTHR43691:SF11; FI09636P-RELATED; 1.
DR PANTHER; PTHR43691; URIDINE PHOSPHORYLASE; 1.
DR Pfam; PF01048; PNP_UDP_1; 1.
DR SUPFAM; SSF53167; Purine and uridine phosphorylases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000588}.
FT DOMAIN 34..266
FT /note="Nucleoside phosphorylase"
FT /evidence="ECO:0000259|Pfam:PF01048"
SQ SEQUENCE 292 AA; 32577 MW; E9D2349A11FFEDAA CRC64;
MKTKRTIPPS ELIINTDGSV FHLHIRPEQL ADKVILVGDP ARVDAVASRF ERIECNVSNR
EFHTVTGWYG DKRITVQSHG IGSDNIDIVL NELDALANID FDTRQVKDRL RKLTLVRVGT
SGGLQDNTPI GSYVAAERSI GFDGVMYFYS DTEKIRDAAF EAALQDQLEW KIEGLKPYVI
PADKTLSDRI CREDILRGVT IAANGFYGPQ GRRLRLPLKD EDLNRKIQAF DFNGSRITNY
EMESSSLAGL AALMGHEAIT VCCIIAGRKS EKMNTSYQGS IEGLIDLVLE RI
//
