ID Q7N6W8_PHOLL Unreviewed; 897 AA.
AC Q7N6W8;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2003, sequence version 1.
DT 27-MAR-2024, entry version 137.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN Name=kdpD {ECO:0000313|EMBL:CAE13710.1};
GN OrderedLocusNames=plu1417 {ECO:0000313|EMBL:CAE13710.1};
OS Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 /
OS TT01) (Photorhabdus luminescens subsp. laumondii).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Photorhabdus.
OX NCBI_TaxID=243265 {ECO:0000313|EMBL:CAE13710.1, ECO:0000313|Proteomes:UP000002514};
RN [1] {ECO:0000313|Proteomes:UP000002514}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15139 / CIP 105565 / TT01
RC {ECO:0000313|Proteomes:UP000002514};
RX PubMed=14528314; DOI=10.1038/nbt886;
RA Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A.,
RA Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F.,
RA Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C.,
RA Lanois A., Powell K., Siguier P., Vincent R., Wingate V., Zouine M.,
RA Glaser P., Boemare N., Danchin A., Kunst F.;
RT "The genome sequence of the entomopathogenic bacterium Photorhabdus
RT luminescens.";
RL Nat. Biotechnol. 21:1307-1313(2003).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; BX571863; CAE13710.1; -; Genomic_DNA.
DR RefSeq; WP_011145723.1; NC_005126.1.
DR AlphaFoldDB; Q7N6W8; -.
DR STRING; 243265.plu1417; -.
DR GeneID; 24167220; -.
DR KEGG; plu:plu1417; -.
DR eggNOG; COG2205; Bacteria.
DR HOGENOM; CLU_000445_113_0_6; -.
DR OrthoDB; 9806130at2; -.
DR Proteomes; UP000002514; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd01987; USP_OKCHK; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.20.120.620; Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038318; KdpD_sf.
DR InterPro; IPR025201; KdpD_TM.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR003852; Sig_transdc_His_kinase_KdpD_N.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF13493; DUF4118; 1.
DR Pfam; PF13492; GAF_3; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF02702; KdpD; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:CAE13710.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000002514};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 403..424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 430..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 454..473
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 479..500
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 675..888
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 897 AA; 101309 MW; 2C7C1C5AA45A3B62 CRC64;
MDQHEPQRPD PDELLTLVNE KQRGKLKIFF GACAGVGKTY AMLQEAQRLR AQGLDVVIGV
VETHERQGTA ALLDGLPQLP LKQIYYRRRK ISVFDLDAAI ARHPAIILMD ELAFSNPHTN
RHPKRWQDVE ELLEAGIDVL TTINVQHLES LNDVVGDITG IRVRETIPDH IFDQANEIVL
VDLPPDDLRQ RLNEGKVYIP SQAERAIEHF FRKGNLIALR ELALRRTADR VDDQMRAFRD
TQGHEPVWHT RDNLLLCIGN SSGNEKLIRT AARLAARLGC IWHAIYVETP KLYQLPEGKR
RSILKALRLA HELGAETATL SDPNKEKAVL RYAREHNLGK ILIGRRCTSK QKLFGWQWRS
GFADRLGKLG PDLDLVIVAL EERSHWDKEQ DNRSVSEKWR VQIQGCLIAI ALCTLITLFS
RTFLLTLDKA NLVTLYLLGV VVIALFYGRR PSIFAAFINV ISFDIFFVQP HWSLAVTDMQ
YLLTFSVMLI VGVVVGNLTA GMRYQARIAR YREQRTRNLY EMTRELSRAL NEEDIARTSY
HFLTNGFQAK TGLFLPNDDG NLYQLTTNNG GHMLIDDAIA KWSFDKNLPA GAGTDTLPSV
PYQLQPIATP SQTLAVLAIE PSYLRQLLIP EQQRLLQTFT GLIANALERL QLSRRAESAK
LDTEREQLRN SLLAALSHDL RTPLTVLFGQ AEILMLDLSA EGSPHTKQVN QIRQQILSTS
RLVNNLLDMA RIQSGGIQLN LEWQSLEEIV GSTLRSLEYA LNRHPVAVSL PSDLLLHCDA
SLLERVFINL LENAIKYTDE QIPLGIKATT EKNQIHIEVW DAGKGIPPEQ EQLIFDKFSR
ARKESAIPGV GLGLAICRAI IEIHQGKIWA SNNEKGGASF HFVLPLEKPP EIITEEM
//
