ID ACTP_PHOLL Reviewed; 549 AA.
AC Q7NA72;
DT 26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-DEC-2003, sequence version 1.
DT 27-MAR-2024, entry version 115.
DE RecName: Full=Cation/acetate symporter ActP {ECO:0000255|HAMAP-Rule:MF_01426};
DE AltName: Full=Acetate permease {ECO:0000255|HAMAP-Rule:MF_01426};
DE AltName: Full=Acetate transporter ActP {ECO:0000255|HAMAP-Rule:MF_01426};
GN Name=actP {ECO:0000255|HAMAP-Rule:MF_01426}; OrderedLocusNames=plu0072;
OS Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 /
OS TT01) (Photorhabdus luminescens subsp. laumondii).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Photorhabdus.
OX NCBI_TaxID=243265;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15139 / CIP 105565 / TT01;
RX PubMed=14528314; DOI=10.1038/nbt886;
RA Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A.,
RA Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F.,
RA Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C.,
RA Lanois A., Powell K., Siguier P., Vincent R., Wingate V., Zouine M.,
RA Glaser P., Boemare N., Danchin A., Kunst F.;
RT "The genome sequence of the entomopathogenic bacterium Photorhabdus
RT luminescens.";
RL Nat. Biotechnol. 21:1307-1313(2003).
CC -!- FUNCTION: Transports acetate. {ECO:0000255|HAMAP-Rule:MF_01426}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01426}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01426}.
CC -!- SIMILARITY: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21)
CC family. {ECO:0000255|HAMAP-Rule:MF_01426}.
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DR EMBL; BX571859; CAE12367.1; -; Genomic_DNA.
DR RefSeq; WP_011144478.1; NC_005126.1.
DR AlphaFoldDB; Q7NA72; -.
DR SMR; Q7NA72; -.
DR STRING; 243265.plu0072; -.
DR GeneID; 24168573; -.
DR KEGG; plu:plu0072; -.
DR eggNOG; COG4147; Bacteria.
DR HOGENOM; CLU_018808_8_3_6; -.
DR OrthoDB; 9764416at2; -.
DR Proteomes; UP000002514; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015123; F:acetate transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0043879; F:glycolate transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR CDD; cd11480; SLC5sbd_u4; 1.
DR Gene3D; 1.20.1730.10; Sodium/glucose cotransporter; 1.
DR HAMAP; MF_01426; Acet_symport_ActP; 1.
DR InterPro; IPR014083; Cation/Ac_symporter_ActP.
DR InterPro; IPR038377; Na/Glc_symporter_sf.
DR InterPro; IPR001734; Na/solute_symporter.
DR InterPro; IPR018212; Na/solute_symporter_CS.
DR NCBIfam; TIGR00813; sss; 1.
DR NCBIfam; TIGR02711; symport_actP; 1.
DR PANTHER; PTHR48086:SF6; CATION_ACETATE SYMPORTER ACTP; 1.
DR PANTHER; PTHR48086; SODIUM/PROLINE SYMPORTER-RELATED; 1.
DR Pfam; PF00474; SSF; 1.
DR PROSITE; PS00456; NA_SOLUT_SYMP_1; 1.
DR PROSITE; PS00457; NA_SOLUT_SYMP_2; 1.
DR PROSITE; PS50283; NA_SOLUT_SYMP_3; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Ion transport; Membrane;
KW Reference proteome; Sodium; Sodium transport; Symport; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..549
FT /note="Cation/acetate symporter ActP"
FT /id="PRO_0000105411"
FT TRANSMEM 32..54
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 75..97
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 102..124
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 145..167
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 182..204
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 211..233
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 263..285
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 298..320
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 361..383
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 404..423
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 428..450
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 462..484
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 494..516
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
SQ SEQUENCE 549 AA; 59598 MW; 8DB76E2C4BAE7E0C CRC64;
MKNFLLLAIM LFPHLTWANV ISETGERQPV NIQAIIMFVL FVGFTLYITY WASKKTRSRT
DYYTAGGRIT GFQNGMAIAG DFMSAASFLG ISALVYTSGY DGLIYSIGFL IGWPIILFLI
AERLRNLGRY TFADVASYRL QQRPIRILSA IGSLFVVALY LIAQMVGAGK LIELLFGLNY
HVAVVLVGIL MVLYVLFGGM LATTWVQIIK AILLLAGATF MALMVMKIVN FNFNTLFKEA
IAVHSRGEAI MSPGGLVSDP ISALSLGLAL MFGTAGLPHI IMRFFTVSDA KEARKSVFYA
TGFIGYFYIL TFIIGFGAIL LVSPNPSFKD TTGALIGGTN MAAVHLASAV GGNLFLGFIS
AVAFATILAV VAGLTLAGAS AVSHDLYANA IKSGKANERD ELRVSKITVV ILGFIAIGLG
ILFENQNIAF MVGLAFSIAA SCNFPIILLS MYWHKLTTRG ALVGGWLGLI TAVVLMILGP
TIWVSILGHE KPIYPYEYPA LFSMIIAFIG SWLFSITDNS QQGMQEREQF RIQFIRSQTG
LGIAQGKTH
//
