ID Q7NF84_GLOVI Unreviewed; 713 AA.
AC Q7NF84;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2003, sequence version 1.
DT 27-MAR-2024, entry version 116.
DE RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN OrderedLocusNames=gll3642 {ECO:0000313|EMBL:BAC91583.1};
OS Gloeobacter violaceus (strain ATCC 29082 / PCC 7421).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Gloeobacterales; Gloeobacteraceae;
OC Gloeobacter.
OX NCBI_TaxID=251221 {ECO:0000313|EMBL:BAC91583.1, ECO:0000313|Proteomes:UP000000557};
RN [1] {ECO:0000313|EMBL:BAC91583.1, ECO:0000313|Proteomes:UP000000557}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29082 / PCC 7421 {ECO:0000313|Proteomes:UP000000557};
RX PubMed=14621292; DOI=10.1093/dnares/10.4.137;
RA Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T.,
RA Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M.,
RA Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M.,
RA Tabata S.;
RT "Complete genome structure of Gloeobacter violaceus PCC 7421, a
RT cyanobacterium that lacks thylakoids.";
RL DNA Res. 10:137-145(2003).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034618};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Couples ATP hydrolysis with the unwinding of duplex DNA by
CC translocating in the 3'-5' direction.; EC=5.6.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00034617};
CC -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC {ECO:0000256|ARBA:ARBA00009922}.
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DR EMBL; BA000045; BAC91583.1; -; Genomic_DNA.
DR RefSeq; NP_926588.1; NC_005125.1.
DR RefSeq; WP_011143631.1; NC_005125.1.
DR AlphaFoldDB; Q7NF84; -.
DR STRING; 251221.gene:10761157; -.
DR EnsemblBacteria; BAC91583; BAC91583; BAC91583.
DR KEGG; gvi:gll3642; -.
DR PATRIC; fig|251221.4.peg.3677; -.
DR eggNOG; COG0210; Bacteria.
DR HOGENOM; CLU_362043_0_0_3; -.
DR InParanoid; Q7NF84; -.
DR OrthoDB; 9765670at2; -.
DR PhylomeDB; Q7NF84; -.
DR Proteomes; UP000000557; Chromosome.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0033202; C:DNA helicase complex; IBA:GO_Central.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0000725; P:recombinational repair; IBA:GO_Central.
DR CDD; cd17932; DEXQc_UvrD; 1.
DR Gene3D; 1.10.10.160; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF00580; UvrD-helicase; 1.
DR Pfam; PF13361; UvrD_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000000557}.
FT DOMAIN 6..307
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 27..34
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 713 AA; 79462 MW; FBC2C0711C17893E CRC64;
MPAYEATLRP AQREVLHYSG GRLGISAVPG SGKTFTLEAL IAELVIRRGV PPERIGVFTF
MRSSRANLTG RINRQLWEGG VAGRLEAFTL HSLALKVLQH FQGQLGLAAI DVLEGYEQER
FISRLTQAWL RNHSEIWEPL LPPTAEAERA ARNRAAFGRG FKAMCREVIR TAKNYRLPPQ
AIEPVQAGFL PWALGIYRSY QAELLRAGKL DYDDLAWRAV DLIERDAGVR GEVEGWYDYL
FEDESQDSSP LQERLLDLLS ARSGNLVRVG DPNQSIMSTF TTAEPRFFRR FCRLSRRVVL
EESSRSAPMI IALANALVDW AASDHPNPSL RGALVRQHIR TASSGPANPG DSEAALHFEV
VCGPPEEELA SVARCAAEAL AARPEHSFAV LVGTNELGAQ VLRQLQRFAG VRTLDLLRSN
PTQRELIDRL RVMAEFFAQP SSPVRLAAAI ESLADWAGLG RRQVAGAQPR LLRIAPEKLL
FPVFGSEIAL PVAAEERAGW QKICSTLAGW LLATRSPRAD SLRLVVQTLY RSSAEIYLGH
YVVDQLERTL GERPAVDWQE VADEIRAILD GSLNNLPSEA FHFAPEPGAI TVATAHRAKG
LEWDEVFLTG ISAYEYPVLR EDRPVGLYFL DGLDMRAEAL SELRASARLR RGHTSATEQA
FLDLAAEKLR LLYVGITRAR RRLVLSVATR DLFGREQRPS RLFQVLQCFD SRR
//
