ID Q7PN80_ANOGA Unreviewed; 949 AA.
AC Q7PN80;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 23-OCT-2007, sequence version 4.
DT 27-MAR-2024, entry version 140.
DE SubName: Full=AGAP007850-PA {ECO:0000313|EMBL:EAA12624.5};
DE Flags: Fragment;
GN ORFNames=AgaP_AGAP007850 {ECO:0000313|EMBL:EAA12624.5};
OS Anopheles gambiae (African malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7165 {ECO:0000313|EMBL:EAA12624.5};
RN [1] {ECO:0000313|EMBL:EAA12624.5}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PEST {ECO:0000313|EMBL:EAA12624.5};
RX PubMed=12364791; DOI=10.1126/science.1076181;
RA Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA Collins F.H., Hoffman S.L.;
RT "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL Science 298:129-149(2002).
RN [2] {ECO:0000313|EMBL:EAA12624.5}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA12624.5};
RG The Anopheles Genome Sequencing Consortium;
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:EAA12624.5}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA12624.5};
RX PubMed=14747013; DOI=10.1016/j.pt.2003.11.003;
RA Mongin E., Louis C., Holt R.A., Birney E., Collins F.H.;
RT "The Anopheles gambiae genome: an update.";
RL Trends Parasitol. 20:49-52(2004).
RN [4] {ECO:0000313|EMBL:EAA12624.5}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA12624.5};
RX PubMed=17210077; DOI=10.1186/gb-2007-8-1-r5;
RA Sharakhova M.V., Hammond M.P., Lobo N.F., Krzywinski J., Unger M.F.,
RA Hillenmeyer M.E., Bruggner R.V., Birney E., Collins F.H.;
RT "Update of the Anopheles gambiae PEST genome assembly.";
RL Genome Biol. 8:R5.1-R5.13(2007).
RN [5] {ECO:0000313|EMBL:EAA12624.5}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA12624.5};
RG VectorBase;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAA12624.5}.
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DR EMBL; AAAB01008964; EAA12624.5; -; Genomic_DNA.
DR RefSeq; XP_317647.4; XM_317647.4.
DR AlphaFoldDB; Q7PN80; -.
DR STRING; 7165.Q7PN80; -.
DR GeneID; 1278110; -.
DR KEGG; aga:AgaP_AGAP007850; -.
DR VEuPathDB; VectorBase:AGAP007849; -.
DR HOGENOM; CLU_000301_0_0_1; -.
DR PhylomeDB; Q7PN80; -.
DR ExpressionAtlas; Q7PN80; differential.
DR GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd00055; EGF_Lam; 8.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 8.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000034; Laminin_IV.
DR InterPro; IPR008211; Laminin_N.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR PANTHER; PTHR10574:SF448; WING BLISTER, ISOFORM B; 1.
DR Pfam; PF00052; Laminin_B; 1.
DR Pfam; PF00053; Laminin_EGF; 9.
DR Pfam; PF00055; Laminin_N; 1.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00181; EGF; 6.
DR SMART; SM00180; EGF_Lam; 9.
DR SMART; SM00281; LamB; 1.
DR SMART; SM00136; LamNT; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 7.
DR PROSITE; PS01248; EGF_LAM_1; 3.
DR PROSITE; PS50027; EGF_LAM_2; 6.
DR PROSITE; PS51115; LAMININ_IVA; 1.
DR PROSITE; PS51117; LAMININ_NTER; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460}.
FT DOMAIN 1..246
FT /note="Laminin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51117"
FT DOMAIN 353..396
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 397..445
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 466..662
FT /note="Laminin IV type A"
FT /evidence="ECO:0000259|PROSITE:PS51115"
FT DOMAIN 700..750
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 813..856
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 857..903
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 904..949
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DISULFID 373..382
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 416..425
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 720..729
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 830..839
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 857..869
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 859..876
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 878..887
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 904..916
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 906..923
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 925..934
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EAA12624.5"
FT NON_TER 949
FT /evidence="ECO:0000313|EMBL:EAA12624.5"
SQ SEQUENCE 949 AA; 103893 MW; 8DCA35FD9455CC42 CRC64;
ASGLWPSFFN VALRATISVN ATCGQTGREE YCRLAEGAGR SRGSQCGICD ANNPDPEKRH
PITNIVDGTN SWWQSPTLQK GAKNDRVTIN LDLGQLYQIV FFTMRAAISP LPAAWVLEKS
MDGRAYDAWQ YFAADDTECR ERFGLPAYTA NYIFKSDTEV ICSTQFSSLE PLENGEINLS
IISGRPSEMI TSPELQNFTL ARYVRIRLLR MQSAEAQRFK TKCFMCTKSF SSRSFYTIRS
LRIGGRCFCS GHAGKCKTMD NNIDNEPQCE CVHNTCGANC DRCCPLYNQR PYRIGTPVAA
NKCEKCEVGN RLLGGVCQNC THHTTGVNCE RCLPGYYRPM DRLPNHPEPC LPCNCTSPGA
VGECSPIGGE CRCLEGFTGA QCTECLPGHS GDRCTRCDCD ARGTLSGREC DERCSCKAHV
VGERCDRCDE GYFALNEDHI DGCLKCYCSG VGTKCSVAHV ETSSYTTLKG WTVTNLAMSE
HIVPTKDNDT GFLVFGMFEM PETEAVYWKA PEGYLGNLLR SYGSQLTFKM DWITVRGDTS
GKPTVGPSLI LVGRNGMKIA YGEESYEETG GATITVPLKE DSWYHVPRTV KDIITRLRRT
EYHGDPVTRS QFMAVLTDVE VVLLRGTYHT DQVESVLEQA DLFSGSHSTT DSSASSSGFI
ELCECPEGYR GTSCEQCAFG YVRIYETSVT HERIGRCIPC SMCNGHAASC DLETGECGLC
LHNTVGTNCE RCLPGFYGNA TLGRPDDCKR CACPLESPSN NFSPNCQSRG GSSDPSEYVC
TQCPEGYTGD HCELCDDGYY GEPTVIGGQC LPCPCHGGPC NAQTGECIEC VGNTEGWRCE
RCKTGYWGVP DDGCEPCSCS ELGALENVCD VTTGQCICKP RYGGRRCDEC DVGYGNLDLD
CPACECNVNG SASTVCNVVS GQCECNVGTE GIHCDRCREE FFGLSDEQP
//
