ID Q7PT66_ANOGA Unreviewed; 550 AA.
AC Q7PT66;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 07-DEC-2004, sequence version 2.
DT 27-MAR-2024, entry version 120.
DE SubName: Full=AGAP007039-PA {ECO:0000313|EMBL:EAA04412.3};
GN Name=1270063 {ECO:0000313|EnsemblMetazoa:AGAP007039-PA};
GN ORFNames=AgaP_AGAP007039 {ECO:0000313|EMBL:EAA04412.3};
OS Anopheles gambiae (African malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7165 {ECO:0000313|EMBL:EAA04412.3};
RN [1] {ECO:0000313|EMBL:EAA04412.3, ECO:0000313|Proteomes:UP000007062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PEST {ECO:0000313|EMBL:EAA04412.3,
RC ECO:0000313|Proteomes:UP000007062};
RX PubMed=12364791; DOI=10.1126/science.1076181;
RA Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA Collins F.H., Hoffman S.L.;
RT "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL Science 298:129-149(2002).
RN [2] {ECO:0000313|EMBL:EAA04412.3}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA04412.3};
RG The Anopheles Genome Sequencing Consortium;
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:EAA04412.3}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA04412.3};
RX PubMed=14747013; DOI=10.1016/j.pt.2003.11.003;
RA Mongin E., Louis C., Holt R.A., Birney E., Collins F.H.;
RT "The Anopheles gambiae genome: an update.";
RL Trends Parasitol. 20:49-52(2004).
RN [4] {ECO:0000313|EMBL:EAA04412.3}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA04412.3};
RX PubMed=17210077; DOI=10.1186/gb-2007-8-1-r5;
RA Sharakhova M.V., Hammond M.P., Lobo N.F., Krzywinski J., Unger M.F.,
RA Hillenmeyer M.E., Bruggner R.V., Birney E., Collins F.H.;
RT "Update of the Anopheles gambiae PEST genome assembly.";
RL Genome Biol. 8:R5.1-R5.13(2007).
RN [5] {ECO:0000313|EMBL:EAA04412.3}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA04412.3};
RG VectorBase;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EnsemblMetazoa:AGAP007039-PA}
RP IDENTIFICATION.
RC STRAIN=PEST {ECO:0000313|EnsemblMetazoa:AGAP007039-PA};
RG EnsemblMetazoa;
RL Submitted (JAN-2021) to UniProtKB.
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DR EMBL; AAAB01008807; EAA04412.3; -; Genomic_DNA.
DR RefSeq; XP_308726.2; XM_308726.3.
DR AlphaFoldDB; Q7PT66; -.
DR PaxDb; 7165-AGAP007039-PA; -.
DR EnsemblMetazoa; AGAP007039-RA; AGAP007039-PA; AGAP007039.
DR GeneID; 1270063; -.
DR KEGG; aga:AgaP_AGAP007039; -.
DR VEuPathDB; VectorBase:AGAP007039; -.
DR eggNOG; KOG0619; Eukaryota.
DR HOGENOM; CLU_538902_0_0_1; -.
DR InParanoid; Q7PT66; -.
DR OMA; MEVHENA; -.
DR OrthoDB; 3428390at2759; -.
DR Proteomes; UP000007062; Chromosome 2L.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24373; SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN; 1.
DR Pfam; PF13855; LRR_8; 2.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00369; LRR_TYP; 7.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000007062};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..550
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014587888"
FT COILED 449..531
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 550 AA; 59930 MW; A5A7F20E09A52ED1 CRC64;
MMFRTRLILL CFLATLLAGQ QATGKPLQFA CASQSSPAAG CLLTGITIRP EDIITSPPGI
RPATDRKITL RQSTVAHMPP TLFEQFPQLE QLNASSIALQ TIPPGCFDKA TKLARLDLSY
NRLQSLPPQA LHKQTALEQL HLQNNSLPTF DAAILPETAP LRTLNLSGNG LTEVRWDPLN
KLRSLETLDV SSNRLATIYV TKSMRVLRAG NNRARTLQTD ANNFLFTLEQ LDLSRNEFAE
LAAVARFAKV THLDASYNRL EAFDFALVRN MRSLVTLNLA HNRLFTVQTT GGSPPTAPGT
LEVVDLSNNF LTVLPSGNAS GVSSARTLHL EGNGLVNLEL HENALYWPRL KSITLGDNDW
HCEFGERISA ILTKRSIAAG GDGERCGREG QVKKGRFCCA VLKNPYLDRL IRTRKELELG
RLAMRDGLAV GAIEAGPPVG DVHKLTDQLR KALMVVSHLR AEKAELEQRN QALAKELEQE
KAKSKSLQEG AAAAAAASRQ SAGTGDLAKE KANLQAALAR AQSEMAGLRA QLTKCTSTVN
TRTGQTVIIQ
//
