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Database: UniProt
Entry: Q7PTN2_ANOGA
LinkDB: Q7PTN2_ANOGA
Original site: Q7PTN2_ANOGA 
ID   Q7PTN2_ANOGA            Unreviewed;       844 AA.
AC   Q7PTN2;
DT   15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT   23-OCT-2007, sequence version 2.
DT   23-MAY-2018, entry version 121.
DE   SubName: Full=AGAP009441-PA {ECO:0000313|EMBL:EAA03632.3};
DE   SubName: Full=Elongation factor 2 {ECO:0000313|VectorBase:AGAP009441-PA, ECO:0000313|VectorBase:AGAP009441-PB};
GN   Name=1269239 {ECO:0000313|VectorBase:AGAP009441-PA,
GN   ECO:0000313|VectorBase:AGAP009441-PB};
GN   ORFNames=AgaP_AGAP009441 {ECO:0000313|EMBL:EAA03632.3};
OS   Anopheles gambiae (African malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Anophelinae; Anopheles.
OX   NCBI_TaxID=7165 {ECO:0000313|EMBL:EAA03632.3, ECO:0000313|Proteomes:UP000007062};
RN   [1] {ECO:0000313|EMBL:EAA03632.3, ECO:0000313|Proteomes:UP000007062, ECO:0000313|VectorBase:AGAP009441-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PEST {ECO:0000313|EMBL:EAA03632.3,
RC   ECO:0000313|Proteomes:UP000007062};
RX   PubMed=12364791; DOI=10.1126/science.1076181;
RA   Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA   Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA   Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B.,
RA   Lai Z., Kraft C.L., Abril J.F., Anthouard V., Arensburger P.,
RA   Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V.,
RA   Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S.,
RA   Center A., Chaturverdi K., Christophides G.K., Chrystal M.A.M.,
RA   Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I.,
RA   Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z.,
RA   Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R.,
RA   Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C.D., Kokoza E.,
RA   Koutsos A., Letunic I., Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F.,
RA   Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J.R.,
RA   Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C.,
RA   Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V.,
RA   Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D.,
RA   Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B., Wang A.H.,
RA   Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A.,
RA   Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA   Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F.,
RA   Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S.,
RA   Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C.,
RA   Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L.;
RT   "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL   Science 298:129-149(2002).
RN   [2] {ECO:0000313|EMBL:EAA03632.3}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PEST {ECO:0000313|EMBL:EAA03632.3};
RG   The Anopheles Genome Sequencing Consortium;
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:EAA03632.3}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PEST {ECO:0000313|EMBL:EAA03632.3};
RX   PubMed=14747013; DOI=10.1016/j.pt.2003.11.003;
RA   Mongin E., Louis C., Holt R.A., Birney E., Collins F.H.;
RT   "The Anopheles gambiae genome: an update.";
RL   Trends Parasitol. 20:49-52(2004).
RN   [4] {ECO:0000313|EMBL:EAA03632.3}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PEST {ECO:0000313|EMBL:EAA03632.3};
RX   PubMed=17210077; DOI=10.1186/gb-2007-8-1-r5;
RA   Sharakhova M.V., Hammond M.P., Lobo N.F., Krzywinski J., Unger M.F.,
RA   Hillenmeyer M.E., Bruggner R.V., Birney E., Collins F.H.;
RT   "Update of the Anopheles gambiae PEST genome assembly.";
RL   Genome Biol. 8:R5-R5(2007).
RN   [5] {ECO:0000313|EMBL:EAA03632.3}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PEST {ECO:0000313|EMBL:EAA03632.3};
RG   VectorBase;
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN   [6] {ECO:0000313|VectorBase:AGAP009441-PA, ECO:0000313|VectorBase:AGAP009441-PB}
RP   IDENTIFICATION.
RC   STRAIN=PEST {ECO:0000313|VectorBase:AGAP009441-PA,
RC   ECO:0000313|VectorBase:AGAP009441-PB};
RG   VectorBase;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   EMBL; AAAB01008797; EAA03632.3; -; Genomic_DNA.
DR   RefSeq; XP_307854.2; XM_307854.4.
DR   ProteinModelPortal; Q7PTN2; -.
DR   STRING; 7165.AGAP009441-PA; -.
DR   EnsemblMetazoa; AGAP009441-RA; AGAP009441-PA; AGAP009441.
DR   EnsemblMetazoa; AGAP009441-RB; AGAP009441-PB; AGAP009441.
DR   GeneID; 1269239; -.
DR   KEGG; aga:AgaP_AGAP009441; -.
DR   VectorBase; AGAP009441-RA; AGAP009441-PA; AGAP009441.
DR   VectorBase; AGAP009441-RB; AGAP009441-PB; AGAP009441.
DR   eggNOG; KOG0469; Eukaryota.
DR   eggNOG; COG0480; LUCA.
DR   HOGENOM; HOG000231589; -.
DR   InParanoid; Q7PTN2; -.
DR   KO; K03234; -.
DR   OMA; EHLISGM; -.
DR   OrthoDB; EOG091G0A2J; -.
DR   PhylomeDB; Q7PTN2; -.
DR   Proteomes; UP000007062; Chromosome 3R.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   Gene3D; 3.30.230.10; -; 2.
DR   InterPro; IPR035647; EFG_III/V.
DR   InterPro; IPR000640; EFG_V-like.
DR   InterPro; IPR004161; EFTu-like_2.
DR   InterPro; IPR031157; G_TR_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   InterPro; IPR014721; Ribosomal_S5_D2-typ_fold_subgr.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR000795; TF_GTP-bd_dom.
DR   InterPro; IPR009000; Transl_B-barrel_sf.
DR   InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR   Pfam; PF00679; EFG_C; 1.
DR   Pfam; PF03764; EFG_IV; 1.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   Pfam; PF03144; GTP_EFTU_D2; 1.
DR   PRINTS; PR00315; ELONGATNFCT.
DR   SMART; SM00838; EFG_C; 1.
DR   SMART; SM00889; EFG_IV; 1.
DR   SUPFAM; SSF50447; SSF50447; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF54211; SSF54211; 1.
DR   SUPFAM; SSF54980; SSF54980; 2.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS00301; G_TR_1; 1.
DR   PROSITE; PS51722; G_TR_2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007062};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007062}.
FT   DOMAIN       17    348       Tr-type G. {ECO:0000259|PROSITE:PS51722}.
SQ   SEQUENCE   844 AA;  94569 MW;  572D941A0A96980E CRC64;
     MVNFTVDEIR AMMDKKRNIR NMSVIAHVDH GKSTLTDSLV SKAGIIAGAK AGETRFTDTR
     KDEQERCITI KSTAISMYFE LDEKDLVFIT NPDQRDKDCK GFLINLIDSP GHVDFSSEVT
     AALRVTDGAL VVVDCVSGVC VQTETVLRQA IAERIKPVLF MNKMDRALLE LQLDPEDLYQ
     TFQRIVENVN VIIATYNDDG GPMGEVRIDP SRGSVGFGSG LHGWAFTLKQ FAEMYSAMFK
     IDVVKLMNRL WGENFFNSKT KKWAKVKDDD NKRSFVMYIL DPIYKVFDAI MNYKTDEIPK
     LLEKIKVSLK HEDKDKDGKN LLKVVMRTWL PAGEALLQMI AIHLPSPVVA QKYRMEMLYE
     GPHDDEAAVA VKNCDPEGPL MMYVSKMVPT SDKGRFYAFG RVFAGKVATG QKCRIMGPNF
     TPGKKEDLYE KAIQRTILMM GRYVEAIEDV PCGNICGLVG VDQFLVKTGT ISTFKDAHNM
     KVMKFSVSPV VRVAVEPKNP ADLPKLVEGL KRLAKSDPMV QCIIEESGEH IIAGAGELHL
     EICLKDLEED HACIPLKKSD PVVSYRETVS DESDQMCLSK SPNKHNRLFM KAVPMPDGLP
     DDIDNGDVNA RDEFKQRARY LSEKYDYDVT EARKIWCFGP DGTGPNIVVD CTKGVQYLNE
     IKDSVVAGFQ WASKEGVLAE ENMRGVRFNI YDVALHADAI HRGGGQIIPT ARRVLYASYI
     TASPRIMEPV YLCEIQCPEA AVGGIYGVLN RRRGHVFEDS QVAGTPMFVV KAYLPVNESF
     GFTADLRSNT GGQAFPQCVF DHWQIFPGDP TDPSTKPYQI IQDIRKRKGL KEGLPDLSQY
     LDKL
//
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