ID Q7PYL7_ANOGA Unreviewed; 398 AA.
AC Q7PYL7;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 23-OCT-2007, sequence version 4.
DT 27-MAR-2024, entry version 109.
DE SubName: Full=AGAP001997-PA {ECO:0000313|EMBL:EAA01244.4};
GN Name=1281124 {ECO:0000313|EnsemblMetazoa:AGAP001997-PA};
GN ORFNames=AgaP_AGAP001997 {ECO:0000313|EMBL:EAA01244.4};
OS Anopheles gambiae (African malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7165 {ECO:0000313|EMBL:EAA01244.4};
RN [1] {ECO:0000313|EMBL:EAA01244.4, ECO:0000313|Proteomes:UP000007062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PEST {ECO:0000313|EMBL:EAA01244.4,
RC ECO:0000313|Proteomes:UP000007062};
RX PubMed=12364791; DOI=10.1126/science.1076181;
RA Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA Collins F.H., Hoffman S.L.;
RT "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL Science 298:129-149(2002).
RN [2] {ECO:0000313|EMBL:EAA01244.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA01244.4};
RG The Anopheles Genome Sequencing Consortium;
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:EAA01244.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA01244.4};
RX PubMed=14747013; DOI=10.1016/j.pt.2003.11.003;
RA Mongin E., Louis C., Holt R.A., Birney E., Collins F.H.;
RT "The Anopheles gambiae genome: an update.";
RL Trends Parasitol. 20:49-52(2004).
RN [4] {ECO:0000313|EMBL:EAA01244.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA01244.4};
RX PubMed=17210077; DOI=10.1186/gb-2007-8-1-r5;
RA Sharakhova M.V., Hammond M.P., Lobo N.F., Krzywinski J., Unger M.F.,
RA Hillenmeyer M.E., Bruggner R.V., Birney E., Collins F.H.;
RT "Update of the Anopheles gambiae PEST genome assembly.";
RL Genome Biol. 8:R5.1-R5.13(2007).
RN [5] {ECO:0000313|EMBL:EAA01244.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA01244.4};
RG VectorBase;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EnsemblMetazoa:AGAP001997-PA}
RP IDENTIFICATION.
RC STRAIN=PEST {ECO:0000313|EnsemblMetazoa:AGAP001997-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AAAB01008987; EAA01244.4; -; Genomic_DNA.
DR RefSeq; XP_321062.4; XM_321062.5.
DR AlphaFoldDB; Q7PYL7; -.
DR STRING; 7165.Q7PYL7; -.
DR PaxDb; 7165-AGAP001997-PA; -.
DR EnsemblMetazoa; AGAP001997-RA; AGAP001997-PA; AGAP001997.
DR GeneID; 1281124; -.
DR KEGG; aga:AgaP_AGAP001997; -.
DR VEuPathDB; VectorBase:AGAP001997; -.
DR eggNOG; KOG3793; Eukaryota.
DR HOGENOM; CLU_064863_1_0_1; -.
DR InParanoid; Q7PYL7; -.
DR OMA; LEPEIHM; -.
DR OrthoDB; 5388448at2759; -.
DR Proteomes; UP000007062; Chromosome 2R.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR GO; GO:0003725; F:double-stranded RNA binding; IBA:GO_Central.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IBA:GO_Central.
DR Gene3D; 1.10.1410.40; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR InterPro; IPR006561; DZF_dom.
DR InterPro; IPR049402; DZF_dom_C.
DR InterPro; IPR049401; DZF_dom_N.
DR InterPro; IPR043519; NT_sf.
DR PANTHER; PTHR46447; INTERLEUKIN ENHANCER-BINDING FACTOR; 1.
DR PANTHER; PTHR46447:SF1; INTERLEUKIN ENHANCER-BINDING FACTOR 2; 1.
DR Pfam; PF20965; DZF_C; 1.
DR Pfam; PF07528; DZF_N; 1.
DR SMART; SM00572; DZF; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR PROSITE; PS50152; 25A_SYNTH_3; 1.
DR PROSITE; PS51703; DZF; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Reference proteome {ECO:0000313|Proteomes:UP000007062}.
FT DOMAIN 30..383
FT /note="DZF"
FT /evidence="ECO:0000259|PROSITE:PS51703"
FT REGION 368..398
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 381..398
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 398 AA; 43984 MW; 14D94E94EE9E6873 CRC64;
MVRPGMMRGG GRGGMGMGMR VRGAPFMNKK TFLPRHPFDL TLAEMAFPRV QPAQDDSVLT
NALLKRSQDL TPAAAEQTAI SNLVSKVQAV LDNIVIAPGD FTKCQLEEVR QVGSFKKGTM
MAGSNVADIV IILKSLPTRD CAEALGKKVE EDLEKSMKTE VVPTAEALSL SFSEKGFEIS
NSLAKVRCLI ATLPQNMRKL ETEKHLDFKI IQSHLAAIRH TRWFEENAHH STIKVLIRIL
KDLARRFDGF KPLNPWICDL LAHSAIMNNP SRQALPVNVA FRRVFQLLAS GLFVPGSAGI
TDPCEVGHFR VHTSMTLVQQ DECCMTAQTL VRVLAHGGYK HILGFVENTT VANEMSVWDG
VVVSPMEPAY EKPSEKKDGE EDDMECVEGE TISEEPIE
//
