ID Q7Q5S0_ANOGA Unreviewed; 722 AA.
AC Q7Q5S0;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 23-OCT-2007, sequence version 4.
DT 24-JAN-2024, entry version 104.
DE SubName: Full=AGAP006240-PA {ECO:0000313|EMBL:EAA10768.4};
GN ORFNames=AgaP_AGAP006240 {ECO:0000313|EMBL:EAA10768.4};
OS Anopheles gambiae (African malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7165 {ECO:0000313|EMBL:EAA10768.4};
RN [1] {ECO:0000313|EMBL:EAA10768.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PEST {ECO:0000313|EMBL:EAA10768.4};
RX PubMed=12364791; DOI=10.1126/science.1076181;
RA Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA Collins F.H., Hoffman S.L.;
RT "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL Science 298:129-149(2002).
RN [2] {ECO:0000313|EMBL:EAA10768.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA10768.4};
RG The Anopheles Genome Sequencing Consortium;
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:EAA10768.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA10768.4};
RX PubMed=14747013; DOI=10.1016/j.pt.2003.11.003;
RA Mongin E., Louis C., Holt R.A., Birney E., Collins F.H.;
RT "The Anopheles gambiae genome: an update.";
RL Trends Parasitol. 20:49-52(2004).
RN [4] {ECO:0000313|EMBL:EAA10768.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA10768.4};
RX PubMed=17210077; DOI=10.1186/gb-2007-8-1-r5;
RA Sharakhova M.V., Hammond M.P., Lobo N.F., Krzywinski J., Unger M.F.,
RA Hillenmeyer M.E., Bruggner R.V., Birney E., Collins F.H.;
RT "Update of the Anopheles gambiae PEST genome assembly.";
RL Genome Biol. 8:R5.1-R5.13(2007).
RN [5] {ECO:0000313|EMBL:EAA10768.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA10768.4};
RG VectorBase;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAA10768.4}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAAB01008960; EAA10768.4; -; Genomic_DNA.
DR RefSeq; XP_316308.4; XM_316308.4.
DR AlphaFoldDB; Q7Q5S0; -.
DR STRING; 7165.Q7Q5S0; -.
DR PaxDb; 7165-AGAP006240-PA; -.
DR GeneID; 1276901; -.
DR KEGG; aga:AgaP_AGAP006240; -.
DR VEuPathDB; VectorBase:AGAP006240; -.
DR eggNOG; KOG2330; Eukaryota.
DR HOGENOM; CLU_014435_0_0_1; -.
DR InParanoid; Q7Q5S0; -.
DR OMA; KGEPIGQ; -.
DR OrthoDB; 5476818at2759; -.
DR PhylomeDB; Q7Q5S0; -.
DR GO; GO:0071013; C:catalytic step 2 spliceosome; IBA:GO_Central.
DR GO; GO:0071011; C:precatalytic spliceosome; IBA:GO_Central.
DR GO; GO:0005689; C:U12-type spliceosomal complex; IBA:GO_Central.
DR GO; GO:0005686; C:U2 snRNP; IBA:GO_Central.
DR GO; GO:0005684; C:U2-type spliceosomal complex; IBA:GO_Central.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR InterPro; IPR007180; DUF382.
DR InterPro; IPR006568; PSP_pro-rich.
DR PANTHER; PTHR12785; SPLICING FACTOR 3B; 1.
DR PANTHER; PTHR12785:SF6; SPLICING FACTOR 3B SUBUNIT 2; 1.
DR Pfam; PF04037; DUF382; 1.
DR Pfam; PF04046; PSP; 1.
DR SMART; SM00581; PSP; 1.
PE 4: Predicted;
FT DOMAIN 405..463
FT /note="PSP proline-rich"
FT /evidence="ECO:0000259|SMART:SM00581"
FT REGION 50..172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 215..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 513..564
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 617..649
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 671..722
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..74
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..99
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 106..149
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..231
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 517..535
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 677..722
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 722 AA; 79464 MW; 0C10B8A62D7080E2 CRC64;
MSLQVDNPDD SAKKPSELVL PKALEDVLAL KTIRAQELGA EETLAAAGSV LPGSYLEQEG
QAESDDENAN EPSAADADGD DSSLHGESED KEDTEPNQGK ELNGDQGKNG DADEAEDEEA
AHRTNGQKED GDAEPVDRAE SEENDKESAP ATKAQPAGEG KKSTPSDDDI LKDVEIEYVP
EKVTIADLGP MYRQFYRVFE IFKLDTKSKE AVKSTEEAEK EKAAAETKKV DDGLDDDDDD
LGDLDEKDDK EKISKRKLKK LNRLTVAELK QLVTRPDVVE MHDVTARDPK LLVQLKSHRN
TVQVPRHWCF KRKYLQGKRG IEKPPFDLPA FIKKTGIMEM RASLQEKDEA KTLKAKMRER
ARPKMGKIDI DYQKLHDAFF KWQTKPRMTI HGDLYYEGKE FETRLKEKKP GDLSEELRIA
LGMPIGPACH KIPPPWLIAQ QRYGPPPSYP NLKIPGLNAP IPEGCSFGYH AGGWGKPPVD
ETGKPLYGDV FGVAGMDGEG GMGEEEIDRT VWGELESESE ESSEEEEDEG EDMTAQPDES
GLITPAEGLV TPSGLTSGVP AGMETPDTIE LRKKKIESEM EDNETPVLYH VLPEKRNERI
GAAMMASTHV YDISAAGGGG PAGAGGGPAA GAGGGRGPGR GGGPVDREGM VELALDPSEL
DLDNEAMAQR YEQQMREQQS HLQKEDLSDM LAEHVARQKS KRKRQQTDTT SKQSKKYKEF
KF
//
