ID Q7Q8Q9_ANOGA Unreviewed; 730 AA.
AC Q7Q8Q9;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 23-OCT-2007, sequence version 4.
DT 24-JAN-2024, entry version 122.
DE SubName: Full=AGAP010610-PA {ECO:0000313|EMBL:EAA09865.4};
DE Flags: Fragment;
GN ORFNames=AgaP_AGAP010610 {ECO:0000313|EMBL:EAA09865.4};
OS Anopheles gambiae (African malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7165 {ECO:0000313|EMBL:EAA09865.4};
RN [1] {ECO:0000313|EMBL:EAA09865.4}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PEST {ECO:0000313|EMBL:EAA09865.4};
RX PubMed=12364791; DOI=10.1126/science.1076181;
RA Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA Collins F.H., Hoffman S.L.;
RT "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL Science 298:129-149(2002).
RN [2] {ECO:0000313|EMBL:EAA09865.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA09865.4};
RG The Anopheles Genome Sequencing Consortium;
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:EAA09865.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA09865.4};
RX PubMed=14747013; DOI=10.1016/j.pt.2003.11.003;
RA Mongin E., Louis C., Holt R.A., Birney E., Collins F.H.;
RT "The Anopheles gambiae genome: an update.";
RL Trends Parasitol. 20:49-52(2004).
RN [4] {ECO:0000313|EMBL:EAA09865.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA09865.4};
RX PubMed=17210077; DOI=10.1186/gb-2007-8-1-r5;
RA Sharakhova M.V., Hammond M.P., Lobo N.F., Krzywinski J., Unger M.F.,
RA Hillenmeyer M.E., Bruggner R.V., Birney E., Collins F.H.;
RT "Update of the Anopheles gambiae PEST genome assembly.";
RL Genome Biol. 8:R5.1-R5.13(2007).
RN [5] {ECO:0000313|EMBL:EAA09865.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA09865.4};
RG VectorBase;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAA09865.4}.
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DR EMBL; AAAB01008933; EAA09865.4; -; Genomic_DNA.
DR RefSeq; XP_314572.4; XM_314572.5.
DR AlphaFoldDB; Q7Q8Q9; -.
DR STRING; 7165.Q7Q8Q9; -.
DR PaxDb; 7165-AGAP010610-PA; -.
DR GeneID; 1275334; -.
DR KEGG; aga:AgaP_AGAP010610; -.
DR VEuPathDB; VectorBase:AGAP010610; -.
DR eggNOG; KOG2177; Eukaryota.
DR HOGENOM; CLU_013730_0_0_1; -.
DR InParanoid; Q7Q8Q9; -.
DR OMA; IAMAGVH; -.
DR OrthoDB; 5475197at2759; -.
DR PhylomeDB; Q7Q8Q9; -.
DR CDD; cd14951; NHL-2_like; 1.
DR CDD; cd03012; TlpA_like_DipZ_like; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 3.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR045302; NHL2_NHL_rpt_dom.
DR InterPro; IPR001258; NHL_repeat.
DR InterPro; IPR012336; Thioredoxin-like_fold.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR46388; NHL REPEAT-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR46388:SF2; NHL REPEAT-CONTAINING PROTEIN 2; 1.
DR Pfam; PF01436; NHL; 2.
DR Pfam; PF13905; Thioredoxin_8; 1.
DR SUPFAM; SSF101898; NHL repeat; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
PE 4: Predicted;
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 85..178
FT /note="Thioredoxin-like fold"
FT /evidence="ECO:0000259|Pfam:PF13905"
FT REGION 600..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EAA09865.4"
FT NON_TER 730
FT /evidence="ECO:0000313|EMBL:EAA09865.4"
SQ SEQUENCE 730 AA; 79556 MW; 0EA751147A105475 CRC64;
AVKIGTRMSS SPEGQDAMEV LACNSNQLAE DLYAAGSNAG RRQKLVHDYL KVADRDGKSV
TAEFPDGLDW FNVTEPLTLQ GSLRGKVVVL DFFTYCCINC MHILPNLKRL EHLYPIEEGL
AVVGVHSAKF RNEKDSANIR AAVERYEISH PVVNDNVSAM WRKLRVQCWP TLMILGPRAN
PLFVIMGEGN YEDLKLYVGS AIRFYREKGE IKRHSLPINL VSSGAIASNM KYPGKVACSV
PTGAGGSEEQ LFAVSDSGNH RVLIVDSAGT VLHKVGGKQS GFVDGNFTKA RFNAPQGVAF
QGTDVVFVAD NENHAVRRID LKARLVSTIA GNGTQGNDRT GGKVGREQLL SSPWDVAVYS
TRDLDMSFHA DEASAPPSKD VLLIAMAGIH QIWALFLQDT IWWKFKKYGA GTCWAIAGNG
HEQNRNTSYP QSAAFAQPSG LAINRTAKEV YLADSESSAI RKISLADGKV MAVAGGDRNP
LDLFAFGDVD GKQYGAKFQH PLGVAYNPQD GFIYFADTYN HKIKKIDAAT NCATTCEFRE
ANGAVRRFNE PAGLCLDRSG QLLYIADTNN HELLVANLTD CTIRPLKLNF RVPEELDSVA
GEAEQGGRRS GTLTLKPARP ITMHPNAGQS SLRLTFNFTF PEQTTKLTEG APQQWSLELP
AGGWSCDSTK GTIDTKTLQL LIALPPGNDA TNGNEPSNPV ALTFKLNLCE GDICFPKEFV
VLLEVQYSAS
//
