ID Q7QJZ4_ANOGA Unreviewed; 585 AA.
AC Q7QJZ4;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 23-OCT-2007, sequence version 4.
DT 27-MAR-2024, entry version 132.
DE SubName: Full=AGAP003902-PA {ECO:0000313|EMBL:EAA03879.4};
GN Name=1269494 {ECO:0000313|EnsemblMetazoa:AGAP003902-PA};
GN ORFNames=AgaP_AGAP003902 {ECO:0000313|EMBL:EAA03879.4};
OS Anopheles gambiae (African malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7165 {ECO:0000313|EMBL:EAA03879.4};
RN [1] {ECO:0000313|EMBL:EAA03879.4, ECO:0000313|Proteomes:UP000007062}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PEST {ECO:0000313|EMBL:EAA03879.4,
RC ECO:0000313|Proteomes:UP000007062};
RX PubMed=12364791; DOI=10.1126/science.1076181;
RA Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R.,
RA Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R.,
RA Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z.,
RA Kraft C.L., Abril J.F., Anthouard V., Arensburger P., Atkinson P.W.,
RA Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C.,
RA Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K.,
RA Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V.,
RA Dana A., Delcher A., Dew I., Evans C.A., Flanigan M.,
RA Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R.,
RA Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J.,
RA Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I.,
RA Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A.,
RA McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D.,
RA O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H.,
RA Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J.,
RA Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B.,
RA Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M.,
RA Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I.,
RA Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J.,
RA Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M.,
RA Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C.,
RA Collins F.H., Hoffman S.L.;
RT "The genome sequence of the malaria mosquito Anopheles gambiae.";
RL Science 298:129-149(2002).
RN [2] {ECO:0000313|EMBL:EAA03879.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA03879.4};
RG The Anopheles Genome Sequencing Consortium;
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:EAA03879.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA03879.4};
RX PubMed=14747013; DOI=10.1016/j.pt.2003.11.003;
RA Mongin E., Louis C., Holt R.A., Birney E., Collins F.H.;
RT "The Anopheles gambiae genome: an update.";
RL Trends Parasitol. 20:49-52(2004).
RN [4] {ECO:0000313|EMBL:EAA03879.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA03879.4};
RX PubMed=17210077; DOI=10.1186/gb-2007-8-1-r5;
RA Sharakhova M.V., Hammond M.P., Lobo N.F., Krzywinski J., Unger M.F.,
RA Hillenmeyer M.E., Bruggner R.V., Birney E., Collins F.H.;
RT "Update of the Anopheles gambiae PEST genome assembly.";
RL Genome Biol. 8:R5.1-R5.13(2007).
RN [5] {ECO:0000313|EMBL:EAA03879.4}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PEST {ECO:0000313|EMBL:EAA03879.4};
RG VectorBase;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EnsemblMetazoa:AGAP003902-PA}
RP IDENTIFICATION.
RC STRAIN=PEST {ECO:0000313|EnsemblMetazoa:AGAP003902-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; AAAB01008805; EAA03879.4; -; Genomic_DNA.
DR RefSeq; XP_308135.4; XM_308135.4.
DR AlphaFoldDB; Q7QJZ4; -.
DR STRING; 7165.Q7QJZ4; -.
DR PaxDb; 7165-AGAP003902-PA; -.
DR EnsemblMetazoa; AGAP003902-RA; AGAP003902-PA; AGAP003902.
DR GeneID; 1269494; -.
DR KEGG; aga:AgaP_AGAP003902; -.
DR VEuPathDB; VectorBase:AGAP003902; -.
DR eggNOG; KOG1174; Eukaryota.
DR HOGENOM; CLU_026953_0_1_1; -.
DR InParanoid; Q7QJZ4; -.
DR OMA; MALAKMF; -.
DR OrthoDB; 6626at2759; -.
DR Proteomes; UP000007062; Chromosome 2R.
DR GO; GO:0005680; C:anaphase-promoting complex; IBA:GO_Central.
DR GO; GO:0051301; P:cell division; IBA:GO_Central.
DR GO; GO:0045842; P:positive regulation of mitotic metaphase/anaphase transition; IBA:GO_Central.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR12558:SF36; ANAPHASE-PROMOTING COMPLEX SUBUNIT 7; 1.
DR PANTHER; PTHR12558; CELL DIVISION CYCLE 16,23,27; 1.
DR Pfam; PF12895; ANAPC3; 1.
DR Pfam; PF13176; TPR_7; 1.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007062};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 237..270
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 306..339
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 476..509
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 523..585
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 523..543
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 585 AA; 66251 MW; 1608D8A0A8DA38AA CRC64;
MKTLFEQLKT LFDYELYSNA ATLANLIISI YDTNRATLSP QEHFGTLVYF AESLFHERRF
REAETIYRQA LQLKRLLTKN KSPNCKTTAG SVPGSVDLQS EVELKYKTAR CLIEMKCYRD
AIVLLQSLAL KQRTPKVNML LSKLCHNHGH ERSAIGTYKE VLKECPLAFE AIEGLLTLGV
KGIEVNSMIV DATMAPQCSE WMSSWIKAHA NIQARKYTEA IQTLRSIEAN TCLRNYHQLL
VLIGECYYHN GDYEQAYITL KRAHAMQPQS KNGLQILALL MAKNKKIAEL EKLITPSPSL
LNEYTSEMWY VMGQYLFATG KYEKAVYFVQ KACFQNSRNV EALVLKAEVL FQVKKYQQGI
AHLRYGQQFA PYRYEIHKAL VDNYLNMGRN REAQLQALKA VKMLGESARM LVLLARTYMK
DEAARPKAKA LCLKALEMSE NFLPAVYLLS EIYLRENDIS TRMKLLKKHV MLSKNSKLHV
MLAETLNNEK DHSGALEHYS IALNLDPSNR VAMSGLLMVG QNKGGTSSSA SNAGASSSYL
ESMAEDGSDV PDNPLEMIEI RTTGANEMES ESDAMWSDLE IEINQ
//
