ID Q7RN02_PLAYO Unreviewed; 629 AA.
AC Q7RN02;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2003, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=Type ii proteins geranylgeranyltransferase beta subunit {ECO:0000313|EMBL:EAA21437.1};
GN ORFNames=PY02024 {ECO:0000313|EMBL:EAA21437.1};
OS Plasmodium yoelii yoelii.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Vinckeia).
OX NCBI_TaxID=73239 {ECO:0000313|EMBL:EAA21437.1, ECO:0000313|Proteomes:UP000008553};
RN [1] {ECO:0000313|EMBL:EAA21437.1, ECO:0000313|Proteomes:UP000008553}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17XNL {ECO:0000313|EMBL:EAA21437.1,
RC ECO:0000313|Proteomes:UP000008553};
RX PubMed=12368865; DOI=10.1038/nature01099;
RA Carlton J.M., Angiuoli S.V., Suh B.B., Kooij T.W., Pertea M., Silva J.C.,
RA Ermolaeva M.D., Allen J.E., Selengut J.D., Koo H.L., Peterson J.D., Pop M.,
RA Kosack D.S., Shumway M.F., Bidwell S.L., Shallom S.J., van Aken S.E.,
RA Riedmuller S.B., Feldblyum T.V., Cho J.K., Quackenbush J., Sedegah M.,
RA Shoaibi A., Cummings L.M., Florens L., Yates J.R., Raine J.D., Sinden R.E.,
RA Harris M.A., Cunningham D.A., Preiser P.R., Bergman L.W., Vaidya A.B.,
RA van Lin L.H., Janse C.J., Waters A.P., Smith H.O., White O.R.,
RA Salzberg S.L., Venter J.C., Fraser C.M., Hoffman S.L., Gardner M.J.,
RA Carucci D.J.;
RT "Genome sequence and comparative analysis of the model rodent malaria
RT parasite Plasmodium yoelii yoelii.";
RL Nature 419:512-519(2002).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the EMC6 family.
CC {ECO:0000256|ARBA:ARBA00009436}.
CC -!- SIMILARITY: Belongs to the protein prenyltransferase subunit beta
CC family. {ECO:0000256|ARBA:ARBA00010497}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAA21437.1}.
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DR EMBL; AABL01000554; EAA21437.1; -; Genomic_DNA.
DR AlphaFoldDB; Q7RN02; -.
DR STRING; 73239.Q7RN02; -.
DR PaxDb; 73239-Q7RN02; -.
DR EnsemblProtists; EAA21437; EAA21437; EAA21437.
DR InParanoid; Q7RN02; -.
DR OMA; DVCYAWW; -.
DR Proteomes; UP000008553; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008318; F:protein prenyltransferase activity; IEA:InterPro.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR Gene3D; 1.50.10.20; -; 1.
DR InterPro; IPR029008; EMC6-like.
DR InterPro; IPR001330; PFTB_repeat.
DR InterPro; IPR045089; PGGT1B-like.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR PANTHER; PTHR11774; GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT; 1.
DR PANTHER; PTHR11774:SF11; GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA; 1.
DR Pfam; PF07019; EMC6; 1.
DR Pfam; PF00432; Prenyltrans; 4.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Prenyltransferase {ECO:0000256|ARBA:ARBA00022602};
KW Reference proteome {ECO:0000313|Proteomes:UP000008553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT TRANSMEM 42..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 67..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 131..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 629 AA; 73057 MW; F7B3AC925B4D56C4 CRC64;
METNASIDNR NKDNIKDSLN SKILESNKYD ENIVKHNKSS LILSRQFYGI IGGITAGILG
LQGIKGFLFF SVFTLIGTLM TFFHIKNNYK SFFSSKSCIF LSDFFSGLIS IKEKLGSKSK
RDYASDKYES ILINGVFWVL SGILIMNKGK NSLSDILEKN VIDMLYLLVM QSLQKKKIKE
DIIYNYKKKN KILSDKDINE VIKIVKRKAY DDVINIKIDN EGTNISMDNI SHYNGKTDEN
INRIEFPKNK EQKINITFNT NENTTNDLLI KNMREIDKVE KKNLNLFQNA THLCGFKNKK
KIKKKFIVCG FSPCNKKWLY ESNVISTLSA IQILFLINRT SENDISTKTL LEIYNFINLM
FDEDKGFYHF SLKSFLLHFD GDMRFVFCSL SSLYFINLLL SKRNIYIYTN NNTQKCINWI
LNCFNVDGGF SKFPGSESHA GTTFCAVNSL NLLKDNNNRS FLFTNKLIRS KLIRWLCDRY
ENQGINGRVS KNHDVCYSWW VLSSLVSLKC NLSKLLNVNI LINFILKCQD KDNGGFSRVQ
QNNNYIKRSE VFNYYDKENI SYKQPDLFHS FFAISALSII YYNIQHYKNK KSDKYDIFGD
IKIPKHLEDQ LIQLNDVHSS FAMPVYMTI
//
