ID Q7RW94_NEUCR Unreviewed; 518 AA.
AC Q7RW94;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 3.
DT 27-MAR-2024, entry version 79.
DE RecName: Full=FAD/NAD(P)-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=NCU07234 {ECO:0000313|EMBL:EAA26652.3};
OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS FGSC 987).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=367110 {ECO:0000313|EMBL:EAA26652.3, ECO:0000313|Proteomes:UP000001805};
RN [1] {ECO:0000313|EMBL:EAA26652.3, ECO:0000313|Proteomes:UP000001805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987
RC {ECO:0000313|Proteomes:UP000001805};
RX PubMed=12712197; DOI=10.1038/nature01554;
RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.,
RA FitzHugh W., Ma L.J., Smirnov S., Purcell S., Rehman B., Elkins T.,
RA Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.,
RA Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA Kothe G.O., Jedd G., Mewes W., Staben C., Marcotte E., Greenberg D.,
RA Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA Kamal M., Kamvysselis M., Mauceli E., Bielke C., Rudd S., Frishman D.,
RA Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA Cogoni C., Macino G., Catcheside D., Li W., Pratt R.J., Osmani S.A.,
RA DeSouza C.P., Glass L., Orbach M.J., Berglund J.A., Voelker R., Yarden O.,
RA Plamann M., Seiler S., Dunlap J., Radford A., Aramayo R., Natvig D.O.,
RA Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S.,
RA Lander E.S., Nusbaum C., Birren B.;
RT "The genome sequence of the filamentous fungus Neurospora crassa.";
RL Nature 422:859-868(2003).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the beta-cyclopiazonate dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00043981}.
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DR EMBL; CM002240; EAA26652.3; -; Genomic_DNA.
DR RefSeq; XP_955888.3; XM_950795.3.
DR AlphaFoldDB; Q7RW94; -.
DR EnsemblFungi; EAA26652; EAA26652; NCU07234.
DR GeneID; 3872035; -.
DR KEGG; ncr:NCU07234; -.
DR VEuPathDB; FungiDB:NCU07234; -.
DR HOGENOM; CLU_028280_0_0_1; -.
DR InParanoid; Q7RW94; -.
DR OrthoDB; 1771364at2759; -.
DR Proteomes; UP000001805; Chromosome 2, Linkage Group V.
DR GO; GO:0016491; F:oxidoreductase activity; IBA:GO_Central.
DR Gene3D; 1.10.405.20; -; 1.
DR Gene3D; 3.30.70.1990; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR42923:SF26; FMN REDUCTASE LOT6, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G06600)-RELATED; 1.
DR PANTHER; PTHR42923; PROTOPORPHYRINOGEN OXIDASE; 1.
DR Pfam; PF13450; NAD_binding_8; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001805};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..518
FT /note="FAD/NAD(P)-binding domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004290883"
SQ SEQUENCE 518 AA; 57084 MW; A8D9FA510D0ECEB2 CRC64;
MTFKGLYNVF LVVASFSSVH AATVNTPKVI ERDVIIIGGG AAGSHAAFRL QQDYNKSIVL
IEKESILGGH VDTYLDTSTT PPTPREYGVQ VYFPYLDGLD FISRFNLTLL PGLGPRGSTT
TRNIDFSTGL ELPANYTGPD PSSITSAIIR FHDLLVSQGW DKMTEPGFWN LPPGPQIPED
LLLPIGEFAK KWNVTEALPR MYESTGGGPA SRHRNFTDTL TLTFLQSFSP AWMKVLYGEV
GMYHIQGGNQ LLYEAIHARL GAAENVLLNS LVSSVRRPAD NADDKRDIQV TITTRVSPLS
RKPTTTTTTI IRARNLLLAI PPTHENLAPF DLDSLESNLF RRAKYGRYGT AIVSSPILPR
GYELHNTPIL AAIDPINKPF INEPHVLEFA SYGNDSDLFS IGTSGSGLGY GEFDEREAIK
VAQESLERMV DAGTVKVPDG NLKKGGGDQK LKVEEYSDHG PGGFGVSAEE MKGGWMEKMY
GLQGRRGTWY TGNAIAIDFS TQLWKMNDEV LRRMLESW
//
