ID Q7RYE4_NEUCR Unreviewed; 1441 AA.
AC Q7RYE4;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2003, sequence version 1.
DT 24-JAN-2024, entry version 99.
DE SubName: Full=Non-repetitive nucleoporin {ECO:0000313|EMBL:EAA27796.1};
GN ORFNames=NCU04463 {ECO:0000313|EMBL:EAA27796.1};
OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS FGSC 987).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=367110 {ECO:0000313|EMBL:EAA27796.1, ECO:0000313|Proteomes:UP000001805};
RN [1] {ECO:0000313|EMBL:EAA27796.1, ECO:0000313|Proteomes:UP000001805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987
RC {ECO:0000313|Proteomes:UP000001805};
RX PubMed=12712197; DOI=10.1038/nature01554;
RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.,
RA FitzHugh W., Ma L.J., Smirnov S., Purcell S., Rehman B., Elkins T.,
RA Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.,
RA Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA Kothe G.O., Jedd G., Mewes W., Staben C., Marcotte E., Greenberg D.,
RA Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA Kamal M., Kamvysselis M., Mauceli E., Bielke C., Rudd S., Frishman D.,
RA Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA Cogoni C., Macino G., Catcheside D., Li W., Pratt R.J., Osmani S.A.,
RA DeSouza C.P., Glass L., Orbach M.J., Berglund J.A., Voelker R., Yarden O.,
RA Plamann M., Seiler S., Dunlap J., Radford A., Aramayo R., Natvig D.O.,
RA Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S.,
RA Lander E.S., Nusbaum C., Birren B.;
RT "The genome sequence of the filamentous fungus Neurospora crassa.";
RL Nature 422:859-868(2003).
CC -!- SIMILARITY: Belongs to the non-repetitive/WGA-negative nucleoporin
CC family. {ECO:0000256|ARBA:ARBA00007373}.
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DR EMBL; CM002239; EAA27796.1; -; Genomic_DNA.
DR RefSeq; XP_957032.1; XM_951939.2.
DR STRING; 367110.Q7RYE4; -.
DR PaxDb; 5141-EFNCRP00000005262; -.
DR EnsemblFungi; EAA27796; EAA27796; NCU04463.
DR GeneID; 23568431; -.
DR KEGG; ncr:NCU04463; -.
DR VEuPathDB; FungiDB:NCU04463; -.
DR HOGENOM; CLU_000429_0_1_1; -.
DR InParanoid; Q7RYE4; -.
DR OMA; SWAPFQK; -.
DR OrthoDB; 52774at2759; -.
DR Proteomes; UP000001805; Chromosome 4, Linkage Group IV.
DR GO; GO:0044611; C:nuclear pore inner ring; IBA:GO_Central.
DR GO; GO:0017056; F:structural constituent of nuclear pore; IBA:GO_Central.
DR GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR GO; GO:0036228; P:protein localization to nuclear inner membrane; IBA:GO_Central.
DR GO; GO:0006405; P:RNA export from nucleus; IBA:GO_Central.
DR GO; GO:0000972; P:transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery; IBA:GO_Central.
DR Gene3D; 1.20.58.1780; -; 1.
DR Gene3D; 1.20.120.1880; Nucleoporin, helical C-terminal domain; 1.
DR Gene3D; 1.25.40.440; Nucleoporin, helical domain, central subdomain; 1.
DR Gene3D; 1.25.40.450; Nucleoporin, helical domain, N-terminal subdomain; 1.
DR InterPro; IPR007187; Nucleoporin_Nup133/Nup155_C.
DR InterPro; IPR014908; Nucleoporin_Nup133/Nup155_N.
DR InterPro; IPR004870; Nucleoporin_Nup155.
DR InterPro; IPR042533; Nucleoporin_Nup155_C_1.
DR InterPro; IPR042537; Nucleoporin_Nup155_C_2.
DR InterPro; IPR042538; Nucleoporin_Nup155_C_3.
DR PANTHER; PTHR10350; NUCLEAR PORE COMPLEX PROTEIN NUP155; 1.
DR PANTHER; PTHR10350:SF6; NUCLEAR PORE COMPLEX PROTEIN NUP155; 1.
DR Pfam; PF03177; Nucleoporin_C; 1.
DR Pfam; PF08801; Nucleoporin_N; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001805};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 147..604
FT /note="Nucleoporin Nup133/Nup155-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08801"
FT DOMAIN 831..1231
FT /note="Nucleoporin Nup133/Nup155-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03177"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1441 AA; 158360 MW; 97E84A81329F55A1 CRC64;
MNPATPMRQV PGAFLNTPAA PRTDDARRYL DSLPEKNTAR PVLGGFGSYN AGGAGVASGP
VTGPVSGSVG GAGAGTVAAP RPVSQVPVPM VPAQARTDLP PVAKAARRIT NTLLRDENYP
DVDSYARAGS SSDYDMYRTD DAPGAPFKKT HMYPIPDQVF ERLNRGEVNT QLGLFADINY
AWAAIDSSLF LWDYTHPNPE LIGYEDATTT ITAVALVPPK PGVFVSNITH ILVVATGTEI
VLLGVSATPT PSGSKTVALY QTKMAVHRGS TDVSLIIGTS NGRIFFGGYT DTDIYELLYQ
QEERWFSSRC AKVNHTHPGW TSVVPNLPVP MGFLGHRDQE HLVQLVVDDT RKLLYSLSDK
STIRTYFMEP SGKLTKVIEK NKVSCLSDMT HMVDLNRNPL LNERVRIVSL SAISAQEASK
SHLMALTNTG CRLFLTATSA ASYMLSASTS LAPQSMQVQY IKFPPTSEDQ QVPLRNEINT
AVAYAPAPAA AQDQMSGLLS ESCLGERFPP GYFFDAVRPK ESRTDLLFVS APDVGRLKQS
AVLRYVEQGT FIPLGDGSRV LSIGLTGNPF AAAKQPLGFG NELAVQFDHT PSEFAVLTNT
GIHIVRRRRF VDIFANAIRV ASGDEDLDSK VKTFTAIYGR VEMVAAALAV ACGQGGDARR
AVDPLTEDRA RSIFINYGGQ PKLADADVLQ APEDNVQLSA RHDALVLYLA RLARTLWKSK
VIEIATDSAS GGFTVGSAIP ISKLMTVQES VQRLRRFLEE NKSLIQGLAG PSDRVSSRQE
EIALQLEHQS LHALRQLMDS VSEGISFVLM LFDERVTDIF MRLDDSSKQQ LQNLTYEALF
SQDSGKELAK VLVKAIVNRN IANGANVETV ADALRRRCGT FCSPDDVVIF KAQEQLQRAS
ESSGNPNLMR TLLAESLRLF SQVAGSLTMT NLRNAVEQYI NLKYYAGAIQ LCLIVAREKD
RGNAALAWFN EGKPANDPRE KAFKDRQSCY SLIHEVLDRL EIESASEPDV VDGRPTLAAT
KRAEAYSVVN SSDDEVFHLD LYDWYIEKGW TDRMLAIDSP HVVTYLQRLA AVDAQHADLL
CRFYTQRSRF FEAAQVQAEL AKSDFPLGIK ERITLLSRAK ANASVTTVGV SRQQQQLLNH
EVTELLEIAH IQDDLLERLR ADPRIVPEKL PDIEKVLDGP VQGLSTLFND FADQAGYYDL
CLLIYNAADY QNPHTIKETW ENLINQIHFE TEQKQEVWRL IEAGEALPEG VEALEVPPPM
PYEAVVSQIQ SIAHRTSLDS LIFPVDTLLP MVCAYAINNH QDASIGADPC WPVAAFLQLG
VPHALIARVL ENMFDAQEAP FVGKHRKLVV QWINCVVDSW IREIEHRGSA SGKNGDGAIT
TWVAELLTRA EEALVAIAAG TRDPAQAASI TDTRRDTREL KRKVEMLSQA EAQGSLLFST
R
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