ID Q7S1X7_NEUCR Unreviewed; 1444 AA.
AC Q7S1X7;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2003, sequence version 1.
DT 24-JAN-2024, entry version 121.
DE SubName: Full=Translation repressor/antiviral protein Ski3 {ECO:0000313|EMBL:EAA29354.1};
GN ORFNames=NCU09438 {ECO:0000313|EMBL:EAA29354.1};
OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS FGSC 987).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=367110 {ECO:0000313|EMBL:EAA29354.1, ECO:0000313|Proteomes:UP000001805};
RN [1] {ECO:0000313|EMBL:EAA29354.1, ECO:0000313|Proteomes:UP000001805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987
RC {ECO:0000313|Proteomes:UP000001805};
RX PubMed=12712197; DOI=10.1038/nature01554;
RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.,
RA FitzHugh W., Ma L.J., Smirnov S., Purcell S., Rehman B., Elkins T.,
RA Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.,
RA Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA Kothe G.O., Jedd G., Mewes W., Staben C., Marcotte E., Greenberg D.,
RA Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA Kamal M., Kamvysselis M., Mauceli E., Bielke C., Rudd S., Frishman D.,
RA Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA Cogoni C., Macino G., Catcheside D., Li W., Pratt R.J., Osmani S.A.,
RA DeSouza C.P., Glass L., Orbach M.J., Berglund J.A., Voelker R., Yarden O.,
RA Plamann M., Seiler S., Dunlap J., Radford A., Aramayo R., Natvig D.O.,
RA Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S.,
RA Lander E.S., Nusbaum C., Birren B.;
RT "The genome sequence of the filamentous fungus Neurospora crassa.";
RL Nature 422:859-868(2003).
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DR EMBL; CM002242; EAA29354.1; -; Genomic_DNA.
DR RefSeq; XP_958590.1; XM_953497.3.
DR STRING; 367110.Q7S1X7; -.
DR PaxDb; 5141-EFNCRP00000009210; -.
DR EnsemblFungi; EAA29354; EAA29354; NCU09438.
DR GeneID; 3874737; -.
DR KEGG; ncr:NCU09438; -.
DR VEuPathDB; FungiDB:NCU09438; -.
DR HOGENOM; CLU_001688_2_0_1; -.
DR InParanoid; Q7S1X7; -.
DR OMA; CQWELDP; -.
DR OrthoDB; 3076611at2759; -.
DR Proteomes; UP000001805; Chromosome 7, Linkage Group VII.
DR GO; GO:0055087; C:Ski complex; IBA:GO_Central.
DR GO; GO:0034427; P:nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'; IBA:GO_Central.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 5.
DR InterPro; IPR039226; Ski3/TTC37.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR040962; TPR_22.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR15704; SUPERKILLER 3 PROTEIN-RELATED; 1.
DR PANTHER; PTHR15704:SF7; TETRATRICOPEPTIDE REPEAT PROTEIN 37; 1.
DR Pfam; PF13432; TPR_16; 2.
DR Pfam; PF14559; TPR_19; 2.
DR Pfam; PF18833; TPR_22; 1.
DR Pfam; PF13174; TPR_6; 1.
DR SMART; SM00028; TPR; 12.
DR SUPFAM; SSF48452; TPR-like; 5.
DR PROSITE; PS50005; TPR; 4.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001805};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 461..494
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 656..689
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 732..765
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 995..1028
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 321..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1444 AA; 161072 MW; 441F1531E0CEB66F CRC64;
MSTKQLVKAA AEAIKKQQWD DAIEGAKNII DKDSKSYQGH ILLAFALDKK GRLEEAENTY
LAATRLKPEE KEAWQGLVKL YPNLDTSKKF KQHQHAVLKL AEIFRDANDL QKCYETVDSF
ITYARNKAES YQYVDALDLI LPGSPIYDAI EGRFGHVWRT YETQAKLVEQ NEKKRINTLI
GERRTRIGAR INEVTLEVKR EVYRQSRLSY TYAQLINWTN DDEVRRMYEE KLIQYCHDRL
MAWPPGEEKE QELANVLKLA NDMVIIKHPY KLAWDIAINW QDHKEIKEWD VTVLRQYCTF
FPDSDLNRVV MGFLTSSVSP FPQEKQEQTT EDAAAKSEGS TEESEDDEDG GAATIYAPIT
EEDRLLMMTE GISGAESLLA FRLMGEYYQH LEEWESNVEL MRKALTFLKE ERAKTGLDFR
FTEDAFSLYL GTALVFYQTP RNHQEAKALF DAVLTHDPTS TPAMIGVGLI YEEEEEYDEA
IDFLERALKR DPNNIRVRTE AAWVKALKGD FDMARAELEA CIPILSKKGQ SKELLSQTQY
RLGYCIWNID TSKAARKDRS GAYALFLESL KNNLNYAPAY TILGIYYADY AKDKKRARRC
FQKAVELSPS EVESAERLAR SFADDGDWDR VELVAQRVVD SGKVKPPPGS KRKGISWPFA
ALGVAELNKQ EFHKAIVSFQ SALRISPNDY HSWVGLGEAY HSSGRYIAAT KAILNAQKLE
ESSEANLTGE TWFTKFILAD IKRELGDFDE SIELYQRVIQ ERPDEEGVAT ALMQTLVDNA
FDSLNKGFFG KAAGLATETL TFATKAPDAI KDTFNYWKAI GDACSLFSNI QGRISEFPAE
TVSSLLGTDE DFPAYQILKD IDNVGTGIVS TDGVFPENET VGVDLTKALQ ATLLAHKRSI
HIASNDIHAQ SVAYYNLGWA EYRAHACLPP DIRKNSHKKP TNYIKAAMAC FKRAIELEAG
NSEFWNALGV VTSEVNPAVA QHAFCRSLFL NERGAHVWAN LATLALAQGD LALANEAFTR
SQSTDPDYSL AWLGQGVVAL LTGNEKDARG LFTHAMEISG DTSRVISQRY AVSMFDHILS
FSSSESLPTT SLIQPIFALT QLQSLHSSAS SSTDLAYNHL LALFLERTGE TPRAISILDS
LSTTLEQEYE TTESPLALKH FAIVKSDLAR LQLSARLFNE AIDSADLALQ LSSDESADEL
TAEERRKLRL SAHVTLGLAH YYSHDITAAV TAFDQALSES NTNPDVACLL AQILWATGQE
DARERGRDLL FGVIADSEER KEQHVQSVLL LGVIALLDND AESMDAVVSE LQSLRSSDEG
ISPEQQAQLG EVLRAILTAM GSGEAQPMTD VMLHPFLPHG WSRVAQLAAQ HGGEEEAEGA
SEMALRVARK GVPPRGELSP EDLARAYAGT GRPADAQVGC VVAPWERRGW ESLGDAVTAV
AAKQ
//
