ID Q7S659_NEUCR Unreviewed; 2055 AA.
AC Q7S659;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2003, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE RecName: Full=MYND-type domain-containing protein {ECO:0000259|PROSITE:PS50865};
GN ORFNames=NCU07116 {ECO:0000313|EMBL:EAA31041.1};
OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS FGSC 987).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=367110 {ECO:0000313|EMBL:EAA31041.1, ECO:0000313|Proteomes:UP000001805};
RN [1] {ECO:0000313|EMBL:EAA31041.1, ECO:0000313|Proteomes:UP000001805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987
RC {ECO:0000313|Proteomes:UP000001805};
RX PubMed=12712197; DOI=10.1038/nature01554;
RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.,
RA FitzHugh W., Ma L.J., Smirnov S., Purcell S., Rehman B., Elkins T.,
RA Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.,
RA Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA Kothe G.O., Jedd G., Mewes W., Staben C., Marcotte E., Greenberg D.,
RA Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA Kamal M., Kamvysselis M., Mauceli E., Bielke C., Rudd S., Frishman D.,
RA Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA Cogoni C., Macino G., Catcheside D., Li W., Pratt R.J., Osmani S.A.,
RA DeSouza C.P., Glass L., Orbach M.J., Berglund J.A., Voelker R., Yarden O.,
RA Plamann M., Seiler S., Dunlap J., Radford A., Aramayo R., Natvig D.O.,
RA Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S.,
RA Lander E.S., Nusbaum C., Birren B.;
RT "The genome sequence of the filamentous fungus Neurospora crassa.";
RL Nature 422:859-868(2003).
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DR EMBL; CM002241; EAA31041.1; -; Genomic_DNA.
DR RefSeq; XP_960277.1; XM_955184.1.
DR PaxDb; 5141-EFNCRP00000006927; -.
DR EnsemblFungi; EAA31041; EAA31041; NCU07116.
DR GeneID; 3876424; -.
DR KEGG; ncr:NCU07116; -.
DR VEuPathDB; FungiDB:NCU07116; -.
DR HOGENOM; CLU_233061_0_0_1; -.
DR InParanoid; Q7S659; -.
DR OMA; CTCHENC; -.
DR OrthoDB; 5474570at2759; -.
DR Proteomes; UP000001805; Chromosome 5, Linkage Group VI.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR Gene3D; 6.10.140.2220; -; 1.
DR InterPro; IPR027974; DUF4470.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR10237:SF13; DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG; 1.
DR PANTHER; PTHR10237; DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG SUPPRESSIN; 1.
DR Pfam; PF14737; DUF4470; 1.
DR Pfam; PF01753; zf-MYND; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001805};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT DOMAIN 1984..2027
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT REGION 158..196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 288..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 592..633
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 709..752
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 938..1018
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1828..1919
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1941..1975
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2030..2055
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..196
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 290..306
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 307..351
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 592..623
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 730..744
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 938..956
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 984..1018
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1850..1879
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1942..1975
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2055 AA; 227183 MW; 948E0ADAB129C7EB CRC64;
MLTPSCPNVT RTFYPFGDTP AVCLTENIPP DKMGEGKPVD ILLLGSGDIR NVFFTTHMDK
TRQLDITCCD VDRLVIARNI LLLTLLIDPD FNINPSSSYA PGLPHPPPTS DDLFAIYYHQ
HLPENLGWLI RSQAMRLRLI GSTMSTWNAS PYGRGQEFQP YPSMSKSKKK KGKGKQNAKD
PIGDAHNSSN PTSGIRFTDS GTLKMLTQIW DAWFCRPDSA QQEALSDGLF KRLGTAVLKR
EQEEVGVPYA ATRAAACSFK AAMPVGLEAT FHATVANEDF WRWGATGSEE RYDEDEDTDE
STDTDSELED NMKKQKKADK GKGKEKERVP SNESRKQAQE RRKKTTKRST DTLQRRVINP
LFTTPSPGVR IDHSCDPLQG FHLAPAYLPI VGQPPPDEGL SQLERLEAVA KQEFADWCNS
FRRAWHKGRI TLRFFIGDAL AFAHTLQHHK AEDLGYPMDT TFGNWYRFRD SFDPLILDSD
DYRIVPSESN RSPAPISFHV IDTSSLADDL GALNVLIAAS PLLENRLAAT LYTEHTLPLP
RPSDSNDARL GPKTPQEVAD TLLHGDLLTM SLLLGLSPVE YYTNTYPSPP PPTFSSPYST
SAPAPPSLGT PSPPPPPAFG ASPAPSSTPT TTPATAAQYF NQRLTWKRPV YHHPTDGSGR
DWTISDKNNI WPGPSPVLRE VMEEFARDFE EFEKTTRELS EHLKALKAEE CEKEEEEEED
KEVEQGKGKG KGKAKKKKKP QKKKTTAKAD IPEHVRNIPP EIREEMLDSR AFQQAAFVLR
DLELRREFRN QKERWENMRT EMPLRKIRFQ ADELVEFLLQ VYSRMYESRY LFERKTDGDG
DGPGDPGVEG STHRHGVGFR LLSPRTCNRA TFASLLKIVQ ERVVILGDPL PTTDPSEDES
IGQMDFTEFL DEMRKTSSEP DRDSVNGEIS EILASTIEAC RSSPDPSTST NSAAVTADGD
DGHRDSATTS NSSDRDANVN PERSDPYEPS SSPVPNLVPC SRFSDSSESD SESSSASTII
TPSAATFSPF FSALPSRPTI AWHHTMEVMI ESLKHSLVNY VETQGSFDQE LCTILHHFGA
YSSPEHAIPD PDALLKPRVY NPAHEAIHSA SKHNTSLYQW INIPSSLAVT VRIPRHSLLT
LKTIMLSLET GLNILRPEIA GGGRGRGKIP ARYVPALQAC IRPTHDHEDK PVANLPGHLF
ASLQTGFGQL ETKGRRFTPR FRLNIETDPL GWEGQSDLFV SFMVPTSILL MDAVTGLVTL
EVVPTIGPDV AGRNELSFMA SGTLKMNLKE PVPPAVKTMM TAKLDENHQR ISSISTRITF
LTDRLLDRLE NRECKIRSVP VTPCSYHLII SRDPTASFFS HGSNNSHLCP VIFLIDIPLP
TNHEKQKIRA GRSKGFIDVE TPIEPFAWRT FFTPSFMHPV HLEQSTQKPM NWSLPYLHSS
NPSSLSSPSS SSGNPLDTLP RLCQSGPLIG CLPDPSFHST NRFCLWWLQL QNHHYQFSRR
EATMHSHFSQ IADPLPKNAS PEEKEKQLKE KDEQFANALN RYLITSGEHA RFEFKITLST
LFDMAAGILR PKSDWRHINP NIMLTPDTQC RSVFALCDFA PSQKSPDCTC HENCLDCGKE
MGSGTGSSVS WSEGAATGNQ PEHSRHGMRR IVIFIAKDGI CLDLAHGTVI LDTAVLVITK
ELRQSLPRYL TDGSIGDPMP IYNQSVMSQS MRTWKEALPA FAERCRGHTW EHGPTCEYKK
KQRAPVANHV QSRKDDPVFC SCSMGRLPKS WSVSEDYPIP QWEEIGPYLV RAAISLPFGC
PGLGEPYQHP MSWDPLLYPH TGPVTGVTPG APGAVTTSAA AAPGRAPVST STPAPATTGI
SQLPSANKIQ ANPTRSAPAS VPTRAIAPTG TRSTLSAKAL EIRPPKPAST STPVAASTGT
GLTQAQAQVL VAKAARLALN PKRPSTSGQS SVQAPSPAST KSASANAKST PTTATTKPTV
RYRCNFCNEP KNRENGGGLN QCSKCKEARY CSKECQVADW KRHKKECDLG AGANAVNGKQ
KVKGNEKQED KKNGK
//
