ID Q7SDJ1_NEUCR Unreviewed; 710 AA.
AC Q7SDJ1;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 2.
DT 27-MAR-2024, entry version 101.
DE SubName: Full=Succinyl-CoA synthetase subunit alpha {ECO:0000313|EMBL:EAA34834.2};
GN ORFNames=NCU09810 {ECO:0000313|EMBL:EAA34834.2};
OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS FGSC 987).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=367110 {ECO:0000313|EMBL:EAA34834.2, ECO:0000313|Proteomes:UP000001805};
RN [1] {ECO:0000313|EMBL:EAA34834.2, ECO:0000313|Proteomes:UP000001805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987
RC {ECO:0000313|Proteomes:UP000001805};
RX PubMed=12712197; DOI=10.1038/nature01554;
RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.,
RA FitzHugh W., Ma L.J., Smirnov S., Purcell S., Rehman B., Elkins T.,
RA Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.,
RA Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA Kothe G.O., Jedd G., Mewes W., Staben C., Marcotte E., Greenberg D.,
RA Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA Kamal M., Kamvysselis M., Mauceli E., Bielke C., Rudd S., Frishman D.,
RA Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA Cogoni C., Macino G., Catcheside D., Li W., Pratt R.J., Osmani S.A.,
RA DeSouza C.P., Glass L., Orbach M.J., Berglund J.A., Voelker R., Yarden O.,
RA Plamann M., Seiler S., Dunlap J., Radford A., Aramayo R., Natvig D.O.,
RA Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S.,
RA Lander E.S., Nusbaum C., Birren B.;
RT "The genome sequence of the filamentous fungus Neurospora crassa.";
RL Nature 422:859-868(2003).
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DR EMBL; CM002236; EAA34834.2; -; Genomic_DNA.
DR RefSeq; XP_964070.2; XM_958977.2.
DR AlphaFoldDB; Q7SDJ1; -.
DR STRING; 367110.Q7SDJ1; -.
DR PaxDb; 5141-EFNCRP00000009560; -.
DR EnsemblFungi; EAA34834; EAA34834; NCU09810.
DR GeneID; 3880210; -.
DR KEGG; ncr:NCU09810; -.
DR VEuPathDB; FungiDB:NCU09810; -.
DR HOGENOM; CLU_015460_0_0_1; -.
DR InParanoid; Q7SDJ1; -.
DR OrthoDB; 1932158at2759; -.
DR Proteomes; UP000001805; Chromosome 1, Linkage Group I.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0009361; C:succinate-CoA ligase complex (ADP-forming); IBA:GO_Central.
DR GO; GO:0004775; F:succinate-CoA ligase (ADP-forming) activity; IBA:GO_Central.
DR GO; GO:0004776; F:succinate-CoA ligase (GDP-forming) activity; IBA:GO_Central.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IBA:GO_Central.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.261; Succinyl-CoA synthetase domains; 2.
DR InterPro; IPR003781; CoA-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR005811; SUCC_ACL_C.
DR InterPro; IPR016102; Succinyl-CoA_synth-like.
DR PANTHER; PTHR11117; SUCCINYL-COA LIGASE SUBUNIT ALPHA; 1.
DR PANTHER; PTHR11117:SF6; SYNTHETASE SUBUNIT ALPHA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G10830)-RELATED; 1.
DR Pfam; PF02629; CoA_binding; 1.
DR Pfam; PF00549; Ligase_CoA; 2.
DR PRINTS; PR01798; SCOASYNTHASE.
DR SMART; SM00881; CoA_binding; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52210; Succinyl-CoA synthetase domains; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001805}.
FT DOMAIN 53..147
FT /note="CoA-binding"
FT /evidence="ECO:0000259|SMART:SM00881"
SQ SEQUENCE 710 AA; 76492 MW; 66C2F5B77353DAA2 CRC64;
MAMYQHARHY SPVHSLRSQW ACRLQMPTSS RRFFTTCQPL HGSYADTLPF LRINSSTRVI
FQGFTGKQAT ANAKDSLAWG TKIVGGVIPG RTGEHLGLPV LPSVRQAMEY LKPDATGIYV
AAHQAPGAIE EAIEAEVPLI VAVAEHIPVH DMLRIHSMLK TQSKSRLVGP NSPGIISAVG
KCRVGFQPLP CFSPGRVGIV AKSGTLSYET VASTTRAGLG QSLCIGVGGD MVPGTDMVEA
LSVLEKDPDT EAIALIGEIG GMGELEAAAW IKEYYSRSKS PKPIIGLIAG VNEAPGRILG
HAGAFTFLGE PTAKAKIAAL EEAGVILVNH PAKIGDTLKT KLREGTTGSG TTSRFQPFAT
GMQRRQLHFM RGPGRRSPAA SLSVHNKQQY QQRRSIYLDV NQCFDELRAR GGINCGLYSG
HGTRRLLAVG IDRSARSPAI LVAPSIEDWM EGAQRTSAPV KSFPFDYRRG PDELAIERLA
SYLQLSNKGD SAVDSLRRLI ETLATLFYEK EGLLLTTHIV ERLRGIKVVH ARFAFDQATF
RNGTPPDKIK AMYVCATDEP AEAKAERSGI VYIKLPGEDA TIGTLVNGAG LAMNTVDALA
DAGGKAANFL DTGGKATSQT VKESFMIILQ DPRVRVIFVN IFGGLTRGDV IAHGIIVAFK
ELSLTVPVVV RIRGTNETEG QKIIADSQLP LYAFDDFEVA AAKAIELSRK
//
