ID Q7SG17_NEUCR Unreviewed; 394 AA.
AC Q7SG17;
DT 15-DEC-2003, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 3.
DT 27-MAR-2024, entry version 118.
DE SubName: Full=Oxidoreductase {ECO:0000313|EMBL:EAA35770.3};
GN ORFNames=NCU02603 {ECO:0000313|EMBL:EAA35770.3};
OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS FGSC 987).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=367110 {ECO:0000313|EMBL:EAA35770.3, ECO:0000313|Proteomes:UP000001805};
RN [1] {ECO:0000313|EMBL:EAA35770.3, ECO:0000313|Proteomes:UP000001805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987
RC {ECO:0000313|Proteomes:UP000001805};
RX PubMed=12712197; DOI=10.1038/nature01554;
RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.,
RA FitzHugh W., Ma L.J., Smirnov S., Purcell S., Rehman B., Elkins T.,
RA Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.,
RA Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA Kothe G.O., Jedd G., Mewes W., Staben C., Marcotte E., Greenberg D.,
RA Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA Kamal M., Kamvysselis M., Mauceli E., Bielke C., Rudd S., Frishman D.,
RA Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA Cogoni C., Macino G., Catcheside D., Li W., Pratt R.J., Osmani S.A.,
RA DeSouza C.P., Glass L., Orbach M.J., Berglund J.A., Voelker R., Yarden O.,
RA Plamann M., Seiler S., Dunlap J., Radford A., Aramayo R., Natvig D.O.,
RA Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S.,
RA Lander E.S., Nusbaum C., Birren B.;
RT "The genome sequence of the filamentous fungus Neurospora crassa.";
RL Nature 422:859-868(2003).
CC -!- SIMILARITY: Belongs to the iron/ascorbate-dependent oxidoreductase
CC family. {ECO:0000256|ARBA:ARBA00008056, ECO:0000256|RuleBase:RU003682}.
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DR EMBL; CM002236; EAA35770.3; -; Genomic_DNA.
DR RefSeq; XP_965006.3; XM_959913.3.
DR AlphaFoldDB; Q7SG17; -.
DR STRING; 367110.Q7SG17; -.
DR PaxDb; 5141-EFNCRP00000002072; -.
DR EnsemblFungi; EAA35770; EAA35770; NCU02603.
DR GeneID; 3881146; -.
DR KEGG; ncr:NCU02603; -.
DR VEuPathDB; FungiDB:NCU02603; -.
DR HOGENOM; CLU_010119_1_1_1; -.
DR InParanoid; Q7SG17; -.
DR OrthoDB; 1380829at2759; -.
DR Proteomes; UP000001805; Chromosome 1, Linkage Group I.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR GO; GO:0044283; P:small molecule biosynthetic process; IEA:UniProt.
DR InterPro; IPR026992; DIOX_N.
DR InterPro; IPR044861; IPNS-like_FE2OG_OXY.
DR InterPro; IPR027443; IPNS-like_sf.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR PANTHER; PTHR47990; 2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED; 1.
DR PANTHER; PTHR47990:SF34; 2-OXOGLUTARATE-DEPENDENT DIOXYGENASE 33; 1.
DR Pfam; PF03171; 2OG-FeII_Oxy; 1.
DR Pfam; PF14226; DIOX_N; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|RuleBase:RU003682};
KW Metal-binding {ECO:0000256|RuleBase:RU003682};
KW Oxidoreductase {ECO:0000256|RuleBase:RU003682};
KW Reference proteome {ECO:0000313|Proteomes:UP000001805}.
FT DOMAIN 174..282
FT /note="Fe2OG dioxygenase"
FT /evidence="ECO:0000259|PROSITE:PS51471"
FT REGION 366..394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 394 AA; 43303 MW; CE35407CDC44C783 CRC64;
MSFTSIPVLD LSLAKDPATK LAFLADLRHA LMEVGFLYLQ NVGISQEVFD QVIREGKGFF
DIPKEEKLKI EMKNAPSFLG YSRLSAEITA GAIDHREQID LSTEHPVPEP GAPLHYNLLA
PNQWPPPNVL PSFRQVFTDY MKKMGEISVY FTSLIAEAIE LPANAFDKYF DKDQQHKLKI
VKYPDVGTLG KEGKEGNQGV GPHKDSMLSS YLLQASHHRG LQVQNMFGQW IDCPPIPGTL
VVAIGQGLEA LTQGVCVSTT HRVLSPAAGE GARFSIPFFQ GVRGDTTFDD LEKVGVGQVP
EHVKEQRRRV LKASGGQRLD DVEFTFRSGG VATTLGEATL RNRVKSHPDV GERWYPEILR
SLREEQSRAA AGSRNSTVGG GAAMVPEGKT VEAH
//
