ID Q7SYP7_XENLA Unreviewed; 259 AA.
AC Q7SYP7;
DT 01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2003, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE RecName: Full=Uroplakin-1b {ECO:0000256|ARBA:ARBA00017701};
DE AltName: Full=Uroplakin Ib {ECO:0000256|ARBA:ARBA00031616};
GN Name=upk1b.L {ECO:0000313|RefSeq:XP_018101318.1,
GN ECO:0000313|RefSeq:XP_018101319.1,
GN ECO:0000313|Xenbase:XB-GENE-17337290};
GN Synonyms=MGC64589 {ECO:0000313|EMBL:AAH54316.1}, upk1b
GN {ECO:0000313|Xenbase:XB-GENE-17337290};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|EMBL:AAH54316.1};
RN [1] {ECO:0000313|EMBL:AAH54316.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Whole {ECO:0000313|EMBL:AAH54316.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|RefSeq:XP_018101318.1, ECO:0000313|RefSeq:XP_018101319.1}
RP IDENTIFICATION.
RC STRAIN=J_2021 {ECO:0000313|RefSeq:XP_018101318.1,
RC ECO:0000313|RefSeq:XP_018101319.1};
RC TISSUE=Erythrocytes {ECO:0000313|RefSeq:XP_018101318.1,
RC ECO:0000313|RefSeq:XP_018101319.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Heterodimer with uroplakin-3A (UPK3A) or uroplakin-3B (UPK3B).
CC {ECO:0000256|ARBA:ARBA00011304}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC054316; AAH54316.1; -; mRNA.
DR RefSeq; XP_018101318.1; XM_018245829.2.
DR RefSeq; XP_018101319.1; XM_018245830.2.
DR DNASU; 398638; -.
DR GeneID; 398638; -.
DR AGR; Xenbase:XB-GENE-17337290; -.
DR CTD; 398638; -.
DR Xenbase; XB-GENE-17337290; upk1b.L.
DR OMA; AECIYFV; -.
DR OrthoDB; 4150771at2759; -.
DR Proteomes; UP000186698; Chromosome 2L.
DR Bgee; 398638; Expressed in gastrula and 10 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd03156; uroplakin_I_like_LEL; 1.
DR Gene3D; 1.10.1450.10; Tetraspanin; 1.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR InterPro; IPR008952; Tetraspanin_EC2_sf.
DR PANTHER; PTHR47110; TESTIS-SPECIFIC EXPRESSED PROTEIN 55; 1.
DR PANTHER; PTHR47110:SF2; UROPLAKIN-1B; 1.
DR Pfam; PF00335; Tetraspanin; 1.
DR PRINTS; PR00259; TMFOUR.
DR SUPFAM; SSF48652; Tetraspanin; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 259 AA; 29321 MW; 056DC8867552A95B CRC64;
MKDDSGIRCF QSLLIFGNVV IGLCGLALTA ECIFFVSDQS GIYPLLEATD NDDIFGAAWI
GIFAGFCLFV LSILGIIGIM KSNRRLLMVY LILMFIVYAF EVASAITAAT QQNFFIPELF
LKQMLEFYQN PNPINNDNLW KINGVTRTWN RFMLLNGCCG VNGPQDWQTY NSVFRQFNSD
SAYPWPQQCC VMNSLGQPVN LDACKLGVAG YVNLNGCYDL MAGPMTRHAW GVAWFGFSIL
CWTFWVLLGS MFYWTRIEY
//
