ID Q7SZH5_ONCMY Unreviewed; 291 AA.
AC Q7SZH5;
DT 01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2003, sequence version 1.
DT 27-MAR-2024, entry version 104.
DE RecName: Full=CCAAT/enhancer-binding protein {ECO:0000256|PIRNR:PIRNR005879};
GN Name=C/EBPbeta {ECO:0000313|EMBL:AAQ18795.1};
GN Synonyms=CEBPB {ECO:0000313|EMBL:ACO08755.1};
GN ORFNames=GSONMT00080971001 {ECO:0000313|EMBL:CDQ60017.1};
OS Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Oncorhynchus.
OX NCBI_TaxID=8022 {ECO:0000313|EMBL:AAN41660.1};
RN [1] {ECO:0000313|EMBL:AAN41660.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Head kidney {ECO:0000313|EMBL:AAN41660.1};
RX PubMed=12774179; DOI=10.1007/s00251-003-0576-7;
RA Fujiki K., Gerwick L., Bayne C.J., Mitchell L., Gauley J., Bols N.,
RA Dixon B.;
RT "Molecular cloning and characterization of rainbow trout (Oncorhynchus
RT mykiss) CCAAT/enhancer binding protein beta.";
RL Immunogenetics 55:253-261(2003).
RN [2] {ECO:0000313|EMBL:AAQ18795.1}
RP NUCLEOTIDE SEQUENCE.
RA Fujiki K., Gerwick L., Bayne C.J., Mitchell L., Gauley J., Bols N.,
RA Dixon B.;
RT "Molecular cloning and characterization of rainbow trout (Oncorhynchus
RT mykiss) CCAAT/enhancer binding protein beta.";
RL Immunogenetics 0:0-0(2003).
RN [3] {ECO:0000313|EMBL:ACO08755.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=White blood cell {ECO:0000313|EMBL:ACO08755.1};
RG cGRASP (B.F. Koop & W.S. Davidson);
RA Yasuike M., von Schalburg K., Cooper G., Leong J., Davidson W.S.,
RA Koop B.F.;
RT "Oncorhynchus mykiss ESTs and full-length cDNAs from White Blood Cells.";
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:CDQ60017.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24755649; DOI=10.1038/ncomms4657;
RA Berthelot C., Brunet F., Chalopin D., Juanchich A., Bernard M., Noel B.,
RA Bento P., Da Silva C., Labadie K., Alberti A., Aury J.M., Louis A.,
RA Dehais P., Bardou P., Montfort J., Klopp C., Cabau C., Gaspin C.,
RA Thorgaard G.H., Boussaha M., Quillet E., Guyomard R., Galiana D., Bobe J.,
RA Volff J.N., Genet C., Wincker P., Jaillon O., Roest Crollius H.,
RA Guiguen Y.;
RT "The rainbow trout genome provides novel insights into evolution after
RT whole-genome duplication in vertebrates.";
RL Nat. Commun. 5:3657-3657(2014).
RN [5] {ECO:0000313|EMBL:CDQ60017.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR005879}.
CC -!- SIMILARITY: Belongs to the bZIP family. C/EBP subfamily.
CC {ECO:0000256|ARBA:ARBA00006951, ECO:0000256|PIRNR:PIRNR005879}.
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DR EMBL; AY144611; AAN41660.1; -; mRNA.
DR EMBL; AY283059; AAQ18795.1; -; Genomic_DNA.
DR EMBL; BT074331; ACO08755.1; -; mRNA.
DR EMBL; FR904339; CDQ60017.1; -; Genomic_DNA.
DR RefSeq; NP_001117919.1; NM_001124447.1.
DR AlphaFoldDB; Q7SZH5; -.
DR STRING; 8022.Q7SZH5; -.
DR PaxDb; 8022-Q7SZH5; -.
DR GeneID; 100136165; -.
DR KEGG; omy:100136165; -.
DR CTD; 1051; -.
DR OrthoDB; 2959124at2759; -.
DR Proteomes; UP000193380; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IDA:AgBase.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0001217; F:DNA-binding transcription repressor activity; IDA:AgBase.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0010628; P:positive regulation of gene expression; IMP:AgBase.
DR GO; GO:0060416; P:response to growth hormone; IMP:AgBase.
DR CDD; cd14712; bZIP_CEBPB; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR InterPro; IPR031106; C/EBP.
DR InterPro; IPR016468; C/EBP_chordates.
DR PANTHER; PTHR23334; CCAAT/ENHANCER BINDING PROTEIN; 1.
DR PANTHER; PTHR23334:SF21; CCAAT_ENHANCER-BINDING PROTEIN BETA; 1.
DR Pfam; PF07716; bZIP_2; 1.
DR PIRSF; PIRSF005879; CCAAT/enhancer-binding; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; Leucine zipper domain; 1.
DR PROSITE; PS50217; BZIP; 1.
PE 2: Evidence at transcript level;
KW Activator {ECO:0000256|PIRNR:PIRNR005879};
KW DNA-binding {ECO:0000256|PIRNR:PIRNR005879};
KW Methylation {ECO:0000256|ARBA:ARBA00022481};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR005879};
KW Reference proteome {ECO:0000313|Proteomes:UP000193380};
KW Transcription {ECO:0000256|PIRNR:PIRNR005879};
KW Transcription regulation {ECO:0000256|PIRNR:PIRNR005879}.
FT DOMAIN 227..290
FT /note="BZIP"
FT /evidence="ECO:0000259|PROSITE:PS50217"
FT REGION 143..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 144..158
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 168..212
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..238
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 291 AA; 32788 MW; 3FA58743C50C4B17 CRC64;
MEVAGFYDRD CFAFQSTNCI IRPISDNSTC KQPIDGSMTE LGIAENEKAI DFSVYLDPPA
AHCQQLATQN ETHQRGVDIF ADFLAEESRI KRRSSLQQNY RNYISLNERE TSVHDNREPY
VLGYPELQET RVDTVFSPEF IGNHFKSGER DESQEDPRMD NGSTGYDMRY LHYQSTPSGS
LGNISTASSS SSSPPGTPAL SGKCTSPSRG GKMSSGVKGK KRLEKNSEEY KQRRERNNLA
VRKSRDKAKM RNTETQHKVL ELAAENDRLQ KRVEQLSREL ATLRNLLSAT G
//
