ID Q7TS04_MOUSE Unreviewed; 311 AA.
AC Q7TS04;
DT 01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2003, sequence version 1.
DT 27-MAR-2024, entry version 148.
DE SubName: Full=Olfactory receptor Olfr301 {ECO:0000313|EMBL:AAP70844.1};
DE SubName: Full=Olfactory receptor family 14 subfamily C member 44 {ECO:0000313|Ensembl:ENSMUSP00000133780.2};
GN Name=Or14c44 {ECO:0000313|Ensembl:ENSMUSP00000133780.2,
GN ECO:0000313|MGI:MGI:3030135};
GN Synonyms=Olfr301 {ECO:0000313|EMBL:AAP70844.1,
GN ECO:0000313|MGI:MGI:3030135};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|EMBL:AAP70844.1};
RN [1] {ECO:0000313|EMBL:AAP70844.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=14611657; DOI=10.1186/gb-2003-4-11-r71;
RA Young J.M., Shykind B.M., Lane R.P., Tonnes-Priddy L., Ross J.A.,
RA Walker M., Williams E.M., Trask B.J.;
RT "Odorant receptor expressed sequence tags demonstrate olfactory expression
RT of over 400 genes, extensive alternate splicing and unequal expression
RT levels.";
RL Genome Biol. 4:R71.1-R71.13(2003).
RN [2] {ECO:0000313|EMBL:AAP70844.1}
RP NUCLEOTIDE SEQUENCE.
RA Sanders K.;
RL Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000133780.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000133780.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [4] {ECO:0000313|Ensembl:ENSMUSP00000133780.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000133780.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AY317394; AAP70844.1; -; Genomic_DNA.
DR RefSeq; NP_997601.1; NM_212436.2.
DR STRING; 10090.ENSMUSP00000133780; -.
DR PaxDb; 10090-ENSMUSP00000133780; -.
DR Ensembl; ENSMUST00000174362.3; ENSMUSP00000133780.2; ENSMUSG00000061549.7.
DR GeneID; 257958; -.
DR KEGG; mmu:257958; -.
DR UCSC; uc009iez.2; mouse.
DR AGR; MGI:3030135; -.
DR CTD; 257958; -.
DR MGI; MGI:3030135; Or14c44.
DR VEuPathDB; HostDB:ENSMUSG00000061549; -.
DR eggNOG; ENOG502SHXQ; Eukaryota.
DR GeneTree; ENSGT01100000263570; -.
DR HOGENOM; CLU_012526_1_2_1; -.
DR OMA; ICACVEI; -.
DR OrthoDB; 4602571at2759; -.
DR BioGRID-ORCS; 257958; 0 hits in 72 CRISPR screens.
DR ChiTaRS; Olfr458; mouse.
DR Proteomes; UP000000589; Chromosome 7.
DR GO; GO:0016020; C:membrane; ISA:MGI.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0005549; F:odorant binding; IBA:GO_Central.
DR GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; ISA:MGI.
DR GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR CDD; cd15227; 7tmA_OR14-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR PANTHER; PTHR26452; OLFACTORY RECEPTOR; 1.
DR PANTHER; PTHR26452:SF159; OLFACTORY RECEPTOR 293-RELATED; 1.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:AAP70844.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022606};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 23..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 58..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 39..289
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 311 AA; 35025 MW; DA1CA04EB4660C9C CRC64;
MSNSTLVTEF MLEDFAENWE LRILLSVLFL LVYLYSLIGN LIIIIATTVD QTLNTPMYFF
LRNLSILDIC YVSVTVPNAC INSLTDHRNI SVGGCAAQIF FVYICACVEI LFLTIMAQDR
YVAICKPLLY PVIMNHWFCV QMTLASLLSS LVLASVHTFK TFQLSFCHSN VVPQFFCDIP
SLLRLSCSDT FNNKLLILLS AILVSGSCFV FIVISYVRIL STVLKVPVKG ERGKAFSTCV
PHIIVVSVFL SSAAYIYLKP PVVTLEVAKE MTLSVFYTIV PPFLNPIIYS LRNRQIKKAV
SKLISRIFFL I
//
