ID   Q7UNI8_RHOBA            Unreviewed;       530 AA.
AC   Q7UNI8;
DT   01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2003, sequence version 1.
DT   27-MAR-2024, entry version 95.
DE   SubName: Full=N-acetylgalactosamine 6-sulfate sulfatase (GALNS) {ECO:0000313|EMBL:CAD75431.1};
DE            EC=3.1.6.4 {ECO:0000313|EMBL:CAD75431.1};
GN   Name=GALNS {ECO:0000313|EMBL:CAD75431.1};
GN   OrderedLocusNames=RB7560 {ECO:0000313|EMBL:CAD75431.1};
OS   Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1).
OC   Bacteria; Planctomycetota; Planctomycetia; Pirellulales; Pirellulaceae;
OC   Rhodopirellula.
OX   NCBI_TaxID=243090 {ECO:0000313|EMBL:CAD75431.1, ECO:0000313|Proteomes:UP000001025};
RN   [1] {ECO:0000313|EMBL:CAD75431.1, ECO:0000313|Proteomes:UP000001025}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10527 / NCIMB 13988 / SH1
RC   {ECO:0000313|Proteomes:UP000001025};
RX   PubMed=12835416; DOI=10.1073/pnas.1431443100;
RA   Gloeckner F.O., Kube M., Bauer M., Teeling H., Lombardot T., Ludwig W.,
RA   Gade D., Beck A., Borzym K., Heitmann K., Rabus R., Schlesner H., Amann R.,
RA   Reinhardt R.;
RT   "Complete genome sequence of the marine planctomycete Pirellula sp. strain
RT   1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:8298-8303(2003).
CC   -!- SIMILARITY: Belongs to the sulfatase family.
CC       {ECO:0000256|ARBA:ARBA00008779}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BX294146; CAD75431.1; -; Genomic_DNA.
DR   RefSeq; NP_867884.1; NC_005027.1.
DR   AlphaFoldDB; Q7UNI8; -.
DR   STRING; 243090.RB7560; -.
DR   EnsemblBacteria; CAD75431; CAD75431; RB7560.
DR   KEGG; rba:RB7560; -.
DR   PATRIC; fig|243090.15.peg.3649; -.
DR   eggNOG; COG3119; Bacteria.
DR   HOGENOM; CLU_006332_10_4_0; -.
DR   InParanoid; Q7UNI8; -.
DR   OrthoDB; 9783154at2; -.
DR   Proteomes; UP000001025; Chromosome.
DR   GO; GO:0004065; F:arylsulfatase activity; IBA:GO_Central.
DR   GO; GO:0043890; F:N-acetylgalactosamine-6-sulfatase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.30.1120.10; -; 1.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR024607; Sulfatase_CS.
DR   InterPro; IPR000917; Sulfatase_N.
DR   PANTHER; PTHR42693:SF33; ARYLSULFATASE; 1.
DR   PANTHER; PTHR42693; ARYLSULFATASE FAMILY MEMBER; 1.
DR   Pfam; PF00884; Sulfatase; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR   PROSITE; PS00523; SULFATASE_1; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:CAD75431.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001025}.
FT   DOMAIN          54..374
FT                   /note="Sulfatase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00884"
SQ   SEQUENCE   530 AA;  59454 MW;  EFC03E10D7194A79 CRC64;
     MRFRLRVGWK GGRVCFFGEQ RMSFRLSGLL CGVVMIVFVT VLGRDLVGDE VDRPNVILVM
     ADDLGYAQTG YFDHPLLKTP ELDRLAAGGL RLDRFYAASA VCSPTRASVL TGRSPERTGV
     PSHGHALRHQ ERSIASAIRK AGYVTGHFGK WHLNGLRGPG VPILGEDRYH PGRFGFDVWL
     SVTNFFDRNP LMSRRGKFEA FEGDSSEVIV KEALDFASRS ARSQQPFFAV VWYGTPHSPF
     VASDEDMQTL VDAGEDEDEK ARLQRIVDGM DEGSRNHYGE LVAMDRSLGT LREGLERLRV
     LDNTLIWFCS DNGGLKGIEP STTEPLRGHK SQLYEGGLRV PCVLHWPDQI QAGRISRVPA
     CATDIAPTLV DLLGLPGDSL TTPVDGISLL PVIQGQDEAV VSHREKPLGF RFRGNSAVVD
     NRWKLIRETR KQKGKSVTSE QLYQLDEDVS ESKDVTGDYP EIASRLSEWL AEWNDSVEDS
     VSGLDYSEGR VNPDHAEPKY WTNDSRYEVF FDEWRDRPEY QSFLKTRLGK
//