ID Q7V9M4_PROMA Unreviewed; 220 AA.
AC Q7V9M4;
DT 01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2003, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=Precorrin isomerase {ECO:0000313|EMBL:AAQ00850.1};
GN Name=cobH {ECO:0000313|EMBL:AAQ00850.1};
GN OrderedLocusNames=Pro_1806 {ECO:0000313|EMBL:AAQ00850.1};
OS Prochlorococcus marinus (strain SARG / CCMP1375 / SS120).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales;
OC Prochlorococcaceae; Prochlorococcus.
OX NCBI_TaxID=167539 {ECO:0000313|EMBL:AAQ00850.1, ECO:0000313|Proteomes:UP000001420};
RN [1] {ECO:0000313|EMBL:AAQ00850.1, ECO:0000313|Proteomes:UP000001420}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SARG / CCMP1375 / SS120 {ECO:0000313|Proteomes:UP000001420};
RX PubMed=12917486; DOI=10.1073/pnas.1733211100;
RA Dufresne A., Salanoubat M., Partensky F., Artiguenave F., Axmann I.M.,
RA Barbe V., Duprat S., Galperin M.Y., Koonin E.V., Le Gall F., Makarova K.S.,
RA Ostrowski M., Oztas S., Robert C., Rogozin I.B., Scanlan D.J.,
RA Tandeau de Marsac N., Weissenbach J., Wincker P., Wolf Y.I., Hess W.R.;
RT "Genome sequence of the cyanobacterium Prochlorococcus marinus SS120, a
RT nearly minimal oxyphototrophic genome.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:10020-10025(2003).
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the CobH/CbiC family.
CC {ECO:0000256|ARBA:ARBA00009774}.
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DR EMBL; AE017126; AAQ00850.1; -; Genomic_DNA.
DR RefSeq; NP_876197.1; NC_005042.1.
DR RefSeq; WP_011125955.1; NC_005042.1.
DR AlphaFoldDB; Q7V9M4; -.
DR STRING; 167539.Pro_1806; -.
DR EnsemblBacteria; AAQ00850; AAQ00850; Pro_1806.
DR KEGG; pma:Pro_1806; -.
DR PATRIC; fig|167539.5.peg.1908; -.
DR eggNOG; COG2082; Bacteria.
DR HOGENOM; CLU_084703_1_1_3; -.
DR OrthoDB; 9780708at2; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000001420; Chromosome.
DR GO; GO:0016993; F:precorrin-8X methylmutase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.10230; Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase; 1.
DR InterPro; IPR003722; Cbl_synth_CobH/CbiC.
DR InterPro; IPR036588; CobH/CbiC_sf.
DR PANTHER; PTHR43588; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR PANTHER; PTHR43588:SF1; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR Pfam; PF02570; CbiC; 1.
DR SUPFAM; SSF63965; Precorrin-8X methylmutase CbiC/CobH; 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:AAQ00850.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001420}.
FT DOMAIN 8..205
FT /note="Cobalamin biosynthesis precorrin-8X methylmutase
FT CobH/CbiC"
FT /evidence="ECO:0000259|Pfam:PF02570"
SQ SEQUENCE 220 AA; 23640 MW; 235B1D7FA8BF0666 CRC64;
MTTIDHPIFD ESVRFIRSRL HCPELDKLEV QVLERLIHTT GDFGIQDYLT FSPNACQLGV
AALQAGAPIL TDTFMAAAAV NPMASRTMQS SVHCILDWAP KKGHSGLTRT ALGIESAWTD
LSKNFNNESS PIILFGSAPK ALEVLLGLIA NGALSPSLII GMPVGFISVL ESKMLLSQMD
LPQIRIDGNR GGAAMAAATV NALLRASWNI KQTNKKLSAE
//
