ID Q7VG76_HELHP Unreviewed; 273 AA.
AC Q7VG76;
DT 01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2003, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=Cytolethal distending toxin CdtB {ECO:0000313|EMBL:AAP78044.1};
GN Name=cdtB {ECO:0000313|EMBL:AAP78044.1};
GN OrderedLocusNames=HH_1447 {ECO:0000313|EMBL:AAP78044.1};
OS Helicobacter hepaticus (strain ATCC 51449 / 3B1).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=235279 {ECO:0000313|EMBL:AAP78044.1, ECO:0000313|Proteomes:UP000002495};
RN [1] {ECO:0000313|EMBL:AAP78044.1, ECO:0000313|Proteomes:UP000002495}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51449 / 3B1 {ECO:0000313|Proteomes:UP000002495};
RX PubMed=12810954; DOI=10.1073/pnas.1332093100;
RA Suerbaum S., Josenhans C., Sterzenbach T., Drescher B., Brandt P., Bell M.,
RA Droege M., Fartmann B., Fischer H.-P., Ge Z., Hoerster A., Holland R.,
RA Klein K., Koenig J., Macko L., Mendz G.L., Nyakatura G., Schauer D.B.,
RA Shen Z., Weber J., Frosch M., Fox J.G.;
RT "The complete genome sequence of the carcinogenic bacterium Helicobacter
RT hepaticus.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:7901-7906(2003).
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DR EMBL; AE017125; AAP78044.1; -; Genomic_DNA.
DR RefSeq; WP_011116287.1; NC_004917.1.
DR AlphaFoldDB; Q7VG76; -.
DR SMR; Q7VG76; -.
DR STRING; 235279.HH_1447; -.
DR GeneID; 82135983; -.
DR KEGG; hhe:HH_1447; -.
DR eggNOG; COG3021; Bacteria.
DR HOGENOM; CLU_091266_0_0_7; -.
DR OrthoDB; 5320299at2; -.
DR Proteomes; UP000002495; Chromosome.
DR GO; GO:0004518; F:nuclease activity; IDA:CACAO.
DR CDD; cd09081; CdtB; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR InterPro; IPR003539; CD_toxinB.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR Pfam; PF03372; Exo_endo_phos; 1.
DR PIRSF; PIRSF018539; CDT_B; 1.
DR PRINTS; PR01388; CDTOXINB.
DR SUPFAM; SSF56219; DNase I-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002495};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..273
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004292496"
FT DOMAIN 25..265
FT /note="Endonuclease/exonuclease/phosphatase"
FT /evidence="ECO:0000259|Pfam:PF03372"
SQ SEQUENCE 273 AA; 29807 MW; EE17B62A2DCFBBC9 CRC64;
MRILLCFLMS FTFALANLED YRVSTWNLQG SSANTESKWN ISVRQLITGD NPANILMVQE
AGAIPASARR TGRMVQPGGT PVEEFTWELG TYSRPNTVYI YYAPLDVGAR RVNLAIVSDR
RADEVLVVHQ NVVATEASRP AIGIRIGNDV FFNIHALASG GGDAPALVTA VHDNFINMPQ
INWLIAGDFN RDPALLQSGL DTRIANHIRI TAPNSATHFS SRGTNRTLDY AVVGRSSPSR
STIVLPQIAA ILMAANIRAH LSSDHSPVHF GRF
//
