ID Q7VH02_HELHP Unreviewed; 823 AA.
AC Q7VH02;
DT 01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2003, sequence version 1.
DT 27-MAR-2024, entry version 97.
DE RecName: Full=Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein {ECO:0000259|SMART:SM00014};
GN OrderedLocusNames=HH_1165 {ECO:0000313|EMBL:AAP77762.1};
OS Helicobacter hepaticus (strain ATCC 51449 / 3B1).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=235279 {ECO:0000313|EMBL:AAP77762.1, ECO:0000313|Proteomes:UP000002495};
RN [1] {ECO:0000313|EMBL:AAP77762.1, ECO:0000313|Proteomes:UP000002495}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51449 / 3B1 {ECO:0000313|Proteomes:UP000002495};
RX PubMed=12810954; DOI=10.1073/pnas.1332093100;
RA Suerbaum S., Josenhans C., Sterzenbach T., Drescher B., Brandt P., Bell M.,
RA Droege M., Fartmann B., Fischer H.-P., Ge Z., Hoerster A., Holland R.,
RA Klein K., Koenig J., Macko L., Mendz G.L., Nyakatura G., Schauer D.B.,
RA Shen Z., Weber J., Frosch M., Fox J.G.;
RT "The complete genome sequence of the carcinogenic bacterium Helicobacter
RT hepaticus.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:7901-7906(2003).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AE017125; AAP77762.1; -; Genomic_DNA.
DR AlphaFoldDB; Q7VH02; -.
DR STRING; 235279.HH_1165; -.
DR KEGG; hhe:HH_1165; -.
DR eggNOG; COG0671; Bacteria.
DR eggNOG; COG2194; Bacteria.
DR HOGENOM; CLU_343813_0_0_7; -.
DR Proteomes; UP000002495; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
DR CDD; cd16017; LptA; 1.
DR CDD; cd01610; PAP2_like; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR Gene3D; 1.20.144.10; Phosphatidic acid phosphatase type 2/haloperoxidase; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR012549; EptA-like_N.
DR InterPro; IPR036938; P_Acid_Pase_2/haloperoxi_sf.
DR InterPro; IPR000326; P_Acid_Pase_2/haloperoxidase.
DR InterPro; IPR040423; PEA_transferase.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR30443; INNER MEMBRANE PROTEIN; 1.
DR PANTHER; PTHR30443:SF0; PHOSPHOETHANOLAMINE TRANSFERASE EPTA; 1.
DR Pfam; PF08019; EptA_B_N; 1.
DR Pfam; PF01569; PAP2; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR SMART; SM00014; acidPPc; 1.
DR SUPFAM; SSF48317; Acid phosphatase/Vanadium-dependent haloperoxidase; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002495};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 249..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 387..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 429..451
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 463..481
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 113..233
FT /note="Phosphatidic acid phosphatase type 2/haloperoxidase"
FT /evidence="ECO:0000259|SMART:SM00014"
SQ SEQUENCE 823 AA; 92067 MW; AF07F4F11261F7C2 CRC64;
MIKLHQRQMT IKLHKFIDNL CIITAMNKQV SMNFAKVNLW HLGVTIGIFC LIVGMLRIFG
WSEPEVYPQI QKDIFLAINS LWSNVPSLAH NLTQLGDASV AFALLLGFLI APKLWEALIA
GSLLSLVLST LFKTIYAMPR PARAFENTFN IIGERLAGTN SLPSGHSITI FTILSVLLFA
FMPSTRKWRL PFIIGITLLG VFVGLSRVGV GAHYPLDVLV GASLGCVCGV FGVLVASKTR
IFAWLDSHFG LLIFATLGAV AVVMAIQNIS KHNLAVFYLA LICASGCLFM MLHKYFTSAQ
RLDLQCTTPP PPPPHPTPSQ PIVFIFIISA LQVAFFHFPF LGFVRTNLAL DSLNAIVLFV
SLVLFLFALT TLMPLLLALI SFKLTKIWFA IISITNAIAV YFVSVYGVFL DKTMMGNLFN
TNPAEAGEFL SLKMALYIVI LGLLPACFLL FEKVARPTRK SLAKSLGLIF FVLIVLTGVN
FQNLLWFDKY SKQLGALIMP WSYIGNSVRY FQGELAKNKK EIPLPDARIT NDKKSVVVLV
IGESARAKNF SLYGYSRNTN PLLLEVSGLR HFYAKSSTTY TSASVKNMLS YKDSTNLYEI
LPNYLARTGV DVMWRSTNWG EPPLHLPSEN IMRYSQLAEK YIHLDDNYES TLVAGLTEDI
ELAKSPKVLI VIHTSTSHGP TYYKKYPPQF EVFKPVCKSV EPKGCLQSEI INAYDNTILY
TDFLLHSVIS QLSKLDKYDS TMIYVSDHGE SLGENGVYMH GIPLAFAPKE QYEIPFFVWS
SNASRIKDLN EATHFHIFHS VLTFLDVESE VLDEKMSIFT KQK
//
