ID Q7VS30_BORPE Unreviewed; 402 AA.
AC Q7VS30;
DT 01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2003, sequence version 1.
DT 27-MAR-2024, entry version 108.
DE SubName: Full=Leu/ile/val-binding protein {ECO:0000313|EMBL:CAE44948.1};
GN OrderedLocusNames=BP0622 {ECO:0000313|EMBL:CAE44948.1};
OS Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=257313 {ECO:0000313|EMBL:CAE44948.1, ECO:0000313|Proteomes:UP000002676};
RN [1] {ECO:0000313|EMBL:CAE44948.1, ECO:0000313|Proteomes:UP000002676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tohama I / ATCC BAA-589 / NCTC 13251
RC {ECO:0000313|Proteomes:UP000002676};
RX PubMed=12910271; DOI=10.1038/ng1227;
RA Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R.,
RA Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L.,
RA Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A.,
RA Achtman M., Atkin R., Baker S., Basham D., Bason N., Cherevach I.,
RA Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T.,
RA Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S.,
RA Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E.,
RA Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M.,
RA Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S.,
RA Barrell B.G., Maskell D.J.;
RT "Comparative analysis of the genome sequences of Bordetella pertussis,
RT Bordetella parapertussis and Bordetella bronchiseptica.";
RL Nat. Genet. 35:32-40(2003).
RN [2] {ECO:0007829|PDB:4MPT}
RP X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS) OF 25-402.
RA Kim Y., Joachimiak G., Clancy S., Joachimiak A.;
RT "Crystal Structure of Periplasmic binding Protein Type 1 from Bordetella
RT pertussis Tohama I.";
RL Submitted (SEP-2013) to the PDB data bank.
RN [3] {ECO:0007829|PDB:4Q6W}
RP X-RAY CRYSTALLOGRAPHY (1.84 ANGSTROMS) OF 3-402 IN COMPLEX WITH
RP 3-HYDROXYBENZOATE.
RA Kim Y., Joachimiak G., Clancy S., Joachimiak A.;
RT "Crystal Structure of Periplasmic Binding Protein type 1 from Bordetella
RT pertussis Tohama I complexed with 3-Hydroxy Benzoic Acid.";
RL Submitted (APR-2014) to the PDB data bank.
CC -!- SIMILARITY: Belongs to the leucine-binding protein family.
CC {ECO:0000256|ARBA:ARBA00010062}.
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DR EMBL; BX640412; CAE44948.1; -; Genomic_DNA.
DR RefSeq; NP_879464.1; NC_002929.2.
DR RefSeq; WP_010929918.1; NZ_CP039022.1.
DR PDB; 4MPT; X-ray; 1.75 A; A/B=25-402.
DR PDB; 4Q6W; X-ray; 1.84 A; A/B=3-402.
DR PDBsum; 4MPT; -.
DR PDBsum; 4Q6W; -.
DR AlphaFoldDB; Q7VS30; -.
DR SMR; Q7VS30; -.
DR STRING; 257313.BP0622; -.
DR PaxDb; 257313-BP0622; -.
DR GeneID; 69600348; -.
DR KEGG; bpe:BP0622; -.
DR PATRIC; fig|257313.5.peg.665; -.
DR eggNOG; COG0683; Bacteria.
DR HOGENOM; CLU_027128_0_0_4; -.
DR Proteomes; UP000002676; Chromosome.
DR GO; GO:0006865; P:amino acid transport; IEA:InterPro.
DR CDD; cd06335; PBP1_ABC_ligand_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR InterPro; IPR028081; Leu-bd.
DR InterPro; IPR000709; Leu_Ile_Val-bd.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30483; LEUCINE-SPECIFIC-BINDING PROTEIN; 1.
DR PANTHER; PTHR30483:SF6; PERIPLASMIC BINDING PROTEIN OF ABC TRANSPORTER FOR NATURAL AMINO ACIDS; 1.
DR Pfam; PF13458; Peripla_BP_6; 1.
DR PRINTS; PR00337; LEUILEVALBP.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:4MPT, ECO:0007829|PDB:4Q6W};
KW Reference proteome {ECO:0000313|Proteomes:UP000002676};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..402
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004292989"
FT DOMAIN 28..389
FT /note="Leucine-binding protein"
FT /evidence="ECO:0000259|Pfam:PF13458"
FT BINDING 107
FT /ligand="3-hydroxybenzoate"
FT /ligand_id="ChEBI:CHEBI:16193"
FT /evidence="ECO:0007829|PDB:4Q6W"
FT BINDING 130
FT /ligand="3-hydroxybenzoate"
FT /ligand_id="ChEBI:CHEBI:16193"
FT /evidence="ECO:0007829|PDB:4Q6W"
FT BINDING 183
FT /ligand="3-hydroxybenzoate"
FT /ligand_id="ChEBI:CHEBI:16193"
FT /evidence="ECO:0007829|PDB:4Q6W"
SQ SEQUENCE 402 AA; 42859 MW; 150BE041A3E263E9 CRC64;
MSWYRKSTTC LAVAAAVLAS GAALAADTIK IGMTSALTGP YNEFGEGNRR AVELAVEQWN
AKGGINGKKI EIAMLLDDQL NPDRAVQNIR AILDNKDIVG IIGPAGSGPM LAVIDMVQAD
GRPYMNPIAQ TPVVTYPGEK TGEKPRPNVF SFALQNDIEA VAMGEYLAKK FKRVGIIHES
TAYGVTGVDY LAASIAKNGG AKPVATDSYN QGAQDMTAQV ARMKRANVDA IAAIGLGKDL
AVLRRTMARL NVNVPLAASN GALGQPYQEG AGELTLGTLG TMIGAFGNPM RAPAADFAKA
YKAKYGTDRW WGNDPENPQL FMAISVSNGY DAANILFEGI RLANSTDPKA VIAAIESIKD
YQGVNTAYTF SKERHHGIET DGVKVFEYVK KGDKIRLEPI AQ
//
