ID Q7Y4P7_BPR69 Unreviewed; 441 AA.
AC Q7Y4P7;
DT 01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2003, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Gp52 topoisomerase II, medium subunit {ECO:0000313|EMBL:AAP76164.1};
GN Name=52 {ECO:0000313|EMBL:AAP76164.1};
OS Escherichia phage RB69 (Bacteriophage RB69).
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Straboviridae; Tevenvirinae; Mosigvirus; Mosigvirus RB69.
OX NCBI_TaxID=12353 {ECO:0000313|EMBL:AAP76164.1, ECO:0000313|Proteomes:UP000000876};
OH NCBI_TaxID=562; Escherichia coli.
RN [1] {ECO:0000313|EMBL:AAP76164.1, ECO:0000313|Proteomes:UP000000876}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=11114936; DOI=10.1128/JB.183.1.358-366.2001;
RA Tetart F., Desplats C., Kutateladze M., Monod C., Ackermann H.W.,
RA Krisch H.M.;
RT "Phylogeny of the major head and tail genes of the wide-ranging T4-type
RT bacteriophages.";
RL J. Bacteriol. 183:358-366(2001).
RN [2] {ECO:0000313|EMBL:AAP76164.1, ECO:0000313|Proteomes:UP000000876}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Petrov V., Nolan J., Chin D., Letarov A., Krisch H.M., Karam J.D.;
RT "Enterobacteria phage RB69 complete genome.";
RL Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the type II topoisomerase family.
CC {ECO:0000256|ARBA:ARBA00011080}.
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DR EMBL; AY303349; AAP76164.1; -; Genomic_DNA.
DR RefSeq; NP_861955.1; NC_004928.1.
DR SMR; Q7Y4P7; -.
DR GeneID; 1494381; -.
DR KEGG; vg:1494381; -.
DR OrthoDB; 2392at10239; -.
DR Proteomes; UP000000876; Genome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:InterPro.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR Gene3D; 3.30.1360.40; -; 1.
DR Gene3D; 3.90.199.10; Topoisomerase II, domain 5; 1.
DR Gene3D; 1.10.268.10; Topoisomerase, domain 3; 1.
DR InterPro; IPR013760; Topo_IIA-like_dom_sf.
DR InterPro; IPR013758; Topo_IIA_A/C_ab.
DR InterPro; IPR013757; Topo_IIA_A_a_sf.
DR InterPro; IPR002205; Topo_IIA_dom_A.
DR InterPro; IPR001154; TopoII_euk.
DR PANTHER; PTHR10169:SF49; DNA TOPOISOMERASE 2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR10169; DNA TOPOISOMERASE/GYRASE; 1.
DR Pfam; PF00521; DNA_topoisoIV; 1.
DR PRINTS; PR01158; TOPISMRASEII.
DR SMART; SM00434; TOP4c; 1.
DR SUPFAM; SSF56719; Type II DNA topoisomerase; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Isomerase {ECO:0000313|EMBL:AAP76164.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000876}.
FT DOMAIN 6..436
FT /note="DNA topoisomerase type IIA"
FT /evidence="ECO:0000259|SMART:SM00434"
SQ SEQUENCE 441 AA; 50410 MW; 0C0C6799A5291076 CRC64;
MQLNSRNLKS IIDNEALAYA MYTVENRAIP NMIDGFKPVQ RFVVHRALDL ARGNKEKFHK
LASIAGGVAD LGYHHGESSA QDAGALMANT WNNNYPLLDG QGNFGSRTVQ KAAASRYIFA
RVSKNFYNVY KDTEYAPAHE DKEHIPPKFY LPIIPTVLLN GVSGIATGYA TNILPHSFKS
VKKAVLQALQ GKNVTKPKVE FPEFRGEVHE VDGRYEIHGT YKFTSRTQMQ ITEIPYKFDR
ETYVSKVLDP LEDKGLISWE DDCGEHGFGF KVKFRKEYSL PDDEELRHEK IMKDFSLIER
RSQNITVINE KGKLAVYDNV VDLIKDFVEV RKTYVQKRID NKILESEKAF KLAFAKAHFI
KKVISGEIVI QGKTRKALTE ELAQIEMYKE HVDKLVGLNI FHITSDESRK LAEEAKAKKE
ENEYWKSTDV VTEYTKDLEA L
//
