ID Q7ZY15_XENLA Unreviewed; 252 AA.
AC Q7ZY15;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE RecName: Full=ER membrane protein complex subunit 3 {ECO:0000256|ARBA:ARBA00020822, ECO:0000256|PIRNR:PIRNR010045};
GN Name=tmem111.S {ECO:0000313|RefSeq:NP_001080238.1,
GN ECO:0000313|Xenbase:XB-GENE-5777244};
GN Synonyms=pob {ECO:0000313|EMBL:AAH44022.1,
GN ECO:0000313|RefSeq:NP_001080238.1}, tmem111
GN {ECO:0000313|RefSeq:NP_001080238.1,
GN ECO:0000313|Xenbase:XB-GENE-5777244}, tmem111.L
GN {ECO:0000313|RefSeq:NP_001080238.1};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|EMBL:AAH44022.1};
RN [1] {ECO:0000313|RefSeq:NP_001080238.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAH44022.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo {ECO:0000313|EMBL:AAH44022.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:NP_001080238.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Component of the ER membrane protein complex (EMC).
CC {ECO:0000256|PIRNR:PIRNR010045}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the EMC3 family. {ECO:0000256|ARBA:ARBA00005376,
CC ECO:0000256|PIRNR:PIRNR010045}.
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DR EMBL; BC044022; AAH44022.1; -; mRNA.
DR RefSeq; NP_001080238.1; NM_001086769.1.
DR STRING; 8355.Q7ZY15; -.
DR PaxDb; 8355-Q7ZY15; -.
DR DNASU; 379930; -.
DR GeneID; 379930; -.
DR KEGG; xla:379930; -.
DR AGR; Xenbase:XB-GENE-5777244; -.
DR CTD; 379930; -.
DR Xenbase; XB-GENE-5777244; tmem111.S.
DR OMA; AMSMPPD; -.
DR OrthoDB; 167603at2759; -.
DR Proteomes; UP000186698; Chromosome 8S.
DR Bgee; 379930; Expressed in pancreas and 19 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR008568; EMC3.
DR InterPro; IPR002809; EMC3/TMCO1.
DR PANTHER; PTHR13116:SF6; ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3; 1.
DR PANTHER; PTHR13116; UNCHARACTERIZED; 1.
DR Pfam; PF01956; EMC3_TMCO1; 1.
DR PIRSF; PIRSF010045; DUF850_TM_euk; 1.
DR SMART; SM01415; DUF106; 1.
PE 2: Evidence at transcript level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 252 AA; 28931 MW; 009C5E1C8445B3C8 CRC64;
MGSPELLLDS SIRLWVVLPI VFITFLTGLL RHHVTRLLQG EKRPELEALS DSQVLIRSRI
LRENGKYIPR QSFLMRKSYF NDNETGFFKK TKRKVIQRNP MTDPTMMTDM MKGNLTNVLP
MILIGGWINW AFSGFLTTKV PFPLTLRFKP MLQRGIELES LDASWVSSAS WYFLNVFGLR
SMYTLLLGQD NAADQSRIMQ DQMTGAALSV PPDTNKAFKA EWEAMEITEH HWALETIEED
LISQDLALAS EQ
//
