ID Q7ZYU4_XENLA Unreviewed; 194 AA.
AC Q7ZYU4;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE RecName: Full=Small ribosomal subunit protein uS4 {ECO:0000256|ARBA:ARBA00035254};
DE AltName: Full=40S ribosomal protein S9 {ECO:0000256|ARBA:ARBA00035410};
GN Name=rps9 {ECO:0000313|RefSeq:NP_001080124.1};
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355 {ECO:0000313|EMBL:AAH41242.1};
RN [1] {ECO:0000313|RefSeq:NP_001080124.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAH41242.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo {ECO:0000313|EMBL:AAH41242.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0007829|PDB:7OYC}
RP STRUCTURE BY ELECTRON MICROSCOPY (2.40 ANGSTROMS).
RX PubMed=36653451; DOI=10.1038/s41586-022-05623-y;
RA Leesch F., Lorenzo-Orts L., Pribitzer C., Grishkovskaya I., Roehsner J.,
RA Chugunova A., Matzinger M., Roitinger E., Belacic K., Kandolf S., Lin T.Y.,
RA Mechtler K., Meinhart A., Haselbach D., Pauli A.;
RT "A molecular network of conserved factors keeps ribosomes dormant in the
RT egg.";
RL Nature 613:712-720(2023).
RN [4] {ECO:0000313|RefSeq:NP_001080124.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS4 family.
CC {ECO:0000256|ARBA:ARBA00007465, ECO:0000256|RuleBase:RU003699}.
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DR EMBL; BC041242; AAH41242.1; -; mRNA.
DR RefSeq; NP_001080124.1; NM_001086655.1.
DR PDB; 7OYC; EM; 2.40 A; J2=1-194.
DR EMDB; EMD-13113; -.
DR IntAct; Q7ZYU4; 1.
DR STRING; 8355.Q7ZYU4; -.
DR PaxDb; 8355-Q7ZYU4; -.
DR DNASU; 379816; -.
DR GeneID; 379816; -.
DR KEGG; xla:379816; -.
DR CTD; 6203; -.
DR OMA; FIRNAAR; -.
DR OrthoDB; 1086372at2759; -.
DR Proteomes; UP000186698; Chromosome 7S.
DR Bgee; 379816; Expressed in pancreas and 19 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0015935; C:small ribosomal subunit; IEA:InterPro.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR CDD; cd00165; S4; 1.
DR Gene3D; 3.10.290.10; RNA-binding S4 domain; 1.
DR InterPro; IPR022801; Ribosomal_uS4.
DR InterPro; IPR018079; Ribosomal_uS4_CS.
DR InterPro; IPR005710; Ribosomal_uS4_euk/arc.
DR InterPro; IPR001912; Ribosomal_uS4_N.
DR InterPro; IPR002942; S4_RNA-bd.
DR InterPro; IPR036986; S4_RNA-bd_sf.
DR NCBIfam; TIGR01018; uS4_arch; 1.
DR PANTHER; PTHR11831; 30S 40S RIBOSOMAL PROTEIN; 1.
DR PANTHER; PTHR11831:SF5; 40S RIBOSOMAL PROTEIN S9; 1.
DR Pfam; PF00163; Ribosomal_S4; 1.
DR Pfam; PF01479; S4; 1.
DR SMART; SM01390; Ribosomal_S4; 1.
DR SMART; SM00363; S4; 1.
DR SUPFAM; SSF55174; Alpha-L RNA-binding motif; 1.
DR PROSITE; PS00632; RIBOSOMAL_S4; 1.
DR PROSITE; PS50889; S4; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:7OYC};
KW Reference proteome {ECO:0000313|Proteomes:UP000186698};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000256|RuleBase:RU003699};
KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980,
KW ECO:0000256|RuleBase:RU003699};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00182};
KW rRNA-binding {ECO:0000256|ARBA:ARBA00022730, ECO:0000256|PROSITE-
KW ProRule:PRU00182}.
FT DOMAIN 1..107
FT /note="Small ribosomal subunit protein uS4 N-terminal"
FT /evidence="ECO:0000259|SMART:SM01390"
FT DOMAIN 108..179
FT /note="RNA-binding S4"
FT /evidence="ECO:0000259|SMART:SM00363"
FT REGION 162..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 194 AA; 22577 MW; 6E7069AE7BFA398C CRC64;
MPVARTWVCR KTYVTPRRPF EKSRLDQELK LIGEYGLRNK REVWRVKFTL AKIRKAARDL
LTLDEKDPKR LFEGNALLRR LVRIGVLDEG KMKLDYILGL KIEDFLERRL QTQVFKLGLA
KSIHHARVLI RQRHIRVRKQ VVNIPSFIVR LDSQKHIDFS LRSPYGGGRP GRVKRKNAKK
GQGGAGAGDE EEED
//
