GenomeNet

Database: UniProt
Entry: Q81LW0
LinkDB: Q81LW0
Original site: Q81LW0 
ID   SODM1_BACAN             Reviewed;         203 AA.
AC   Q81LW0; Q6HTB2; Q6KMK4;
DT   29-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   13-FEB-2019, entry version 109.
DE   RecName: Full=Superoxide dismutase [Mn] 1;
DE            EC=1.15.1.1;
GN   Name=sodA1; Synonyms=sodA-1;
GN   OrderedLocusNames=BA_4499, GBAA_4499, BAS4177;
OS   Bacillus anthracis.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=1392;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ames / isolate Porton;
RX   PubMed=12721629; DOI=10.1038/nature01586;
RA   Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T.,
RA   Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R.,
RA   Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M.,
RA   Kolonay J.F., Beanan M.J., Dodson R.J., Brinkac L.M., Gwinn M.L.,
RA   DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H.,
RA   Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D.,
RA   Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F.,
RA   Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C.,
RA   Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O.,
RA   Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M.,
RA   Hanna P.C., Kolstoe A.-B., Fraser C.M.;
RT   "The genome sequence of Bacillus anthracis Ames and comparison to
RT   closely related bacteria.";
RL   Nature 423:81-86(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ames ancestor;
RX   PubMed=18952800; DOI=10.1128/JB.01347-08;
RA   Ravel J., Jiang L., Stanley S.T., Wilson M.R., Decker R.S., Read T.D.,
RA   Worsham P., Keim P.S., Salzberg S.L., Fraser-Liggett C.M., Rasko D.A.;
RT   "The complete genome sequence of Bacillus anthracis Ames 'Ancestor'.";
RL   J. Bacteriol. 191:445-446(2009).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Sterne;
RA   Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K.,
RA   Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R.,
RA   Richardson P., Rubin E., Tice H.;
RT   "Complete genome sequence of Bacillus anthracis Sterne.";
RL   Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Destroys superoxide anion radicals which are normally
CC       produced within the cells and which are toxic to biological
CC       systems.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + 2 superoxide = H2O2 + O2; Xref=Rhea:RHEA:20696,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240,
CC         ChEBI:CHEBI:18421; EC=1.15.1.1;
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250};
CC       Note=Binds 1 Mn(2+) ion per subunit. {ECO:0000250};
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the iron/manganese superoxide dismutase
CC       family. {ECO:0000305}.
DR   EMBL; AE016879; AAP28210.1; -; Genomic_DNA.
DR   EMBL; AE017334; AAT33618.1; -; Genomic_DNA.
DR   EMBL; AE017225; AAT56477.1; -; Genomic_DNA.
DR   RefSeq; NP_846724.1; NC_003997.3.
DR   RefSeq; WP_001052031.1; NZ_QPKQ01000004.1.
DR   RefSeq; YP_030426.1; NC_005945.1.
DR   PDB; 1XUQ; X-ray; 1.80 A; A/B=1-203.
DR   PDBsum; 1XUQ; -.
DR   ProteinModelPortal; Q81LW0; -.
DR   SMR; Q81LW0; -.
DR   STRING; 260799.BAS4177; -.
DR   DNASU; 1088022; -.
DR   EnsemblBacteria; AAP28210; AAP28210; BA_4499.
DR   EnsemblBacteria; AAT33618; AAT33618; GBAA_4499.
DR   EnsemblBacteria; AAT56477; AAT56477; BAS4177.
DR   GeneID; 1088022; -.
DR   GeneID; 2851955; -.
DR   GeneID; 31628265; -.
DR   KEGG; ban:BA_4499; -.
DR   KEGG; bar:GBAA_4499; -.
DR   KEGG; bat:BAS4177; -.
DR   PATRIC; fig|198094.11.peg.4467; -.
DR   eggNOG; ENOG4105CK4; Bacteria.
DR   eggNOG; COG0605; LUCA.
DR   HOGENOM; HOG000013583; -.
DR   KO; K04564; -.
DR   BioCyc; ANTHRA:SODA-1-MONOMER; -.
DR   BioCyc; BANT260799:BAS4177-MONOMER; -.
DR   EvolutionaryTrace; Q81LW0; -.
DR   Proteomes; UP000000427; Chromosome.
DR   Proteomes; UP000000594; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004784; F:superoxide dismutase activity; ISS:TIGR.
DR   GO; GO:0019430; P:removal of superoxide radicals; ISS:TIGR.
DR   Gene3D; 1.10.287.990; -; 1.
DR   Gene3D; 2.40.500.20; -; 1.
DR   InterPro; IPR001189; Mn/Fe_SOD.
DR   InterPro; IPR019833; Mn/Fe_SOD_BS.
DR   InterPro; IPR019832; Mn/Fe_SOD_C.
DR   InterPro; IPR019831; Mn/Fe_SOD_N.
DR   InterPro; IPR036324; Mn/Fe_SOD_N_sf.
DR   InterPro; IPR036314; SOD_C_sf.
DR   Pfam; PF02777; Sod_Fe_C; 1.
DR   Pfam; PF00081; Sod_Fe_N; 1.
DR   PIRSF; PIRSF000349; SODismutase; 1.
DR   PRINTS; PR01703; MNSODISMTASE.
DR   SUPFAM; SSF46609; SSF46609; 1.
DR   SUPFAM; SSF54719; SSF54719; 1.
DR   PROSITE; PS00088; SOD_MN; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Complete proteome; Manganese; Metal-binding;
KW   Oxidoreductase; Reference proteome.
FT   CHAIN         1    203       Superoxide dismutase [Mn] 1.
FT                                /FTId=PRO_0000160012.
FT   METAL        28     28       Manganese. {ECO:0000250}.
FT   METAL        83     83       Manganese. {ECO:0000250}.
FT   METAL       165    165       Manganese. {ECO:0000250}.
FT   METAL       169    169       Manganese. {ECO:0000250}.
FT   TURN         13     19       {ECO:0000244|PDB:1XUQ}.
FT   HELIX        22     30       {ECO:0000244|PDB:1XUQ}.
FT   HELIX        32     44       {ECO:0000244|PDB:1XUQ}.
FT   HELIX        48     51       {ECO:0000244|PDB:1XUQ}.
FT   HELIX        55     60       {ECO:0000244|PDB:1XUQ}.
FT   HELIX        62     64       {ECO:0000244|PDB:1XUQ}.
FT   HELIX        67     88       {ECO:0000244|PDB:1XUQ}.
FT   HELIX       100    110       {ECO:0000244|PDB:1XUQ}.
FT   HELIX       113    126       {ECO:0000244|PDB:1XUQ}.
FT   STRAND      129    138       {ECO:0000244|PDB:1XUQ}.
FT   STRAND      141    148       {ECO:0000244|PDB:1XUQ}.
FT   HELIX       153    156       {ECO:0000244|PDB:1XUQ}.
FT   STRAND      159    165       {ECO:0000244|PDB:1XUQ}.
FT   HELIX       168    170       {ECO:0000244|PDB:1XUQ}.
FT   HELIX       172    175       {ECO:0000244|PDB:1XUQ}.
FT   HELIX       179    186       {ECO:0000244|PDB:1XUQ}.
FT   TURN        187    189       {ECO:0000244|PDB:1XUQ}.
FT   HELIX       192    201       {ECO:0000244|PDB:1XUQ}.
SQ   SEQUENCE   203 AA;  22664 MW;  61B0B7D44A090D97 CRC64;
     MAKHELPNLP YAYDALEPHF DKETMNIHHT KHHNTYITNL NAALEGHAEL ADKSVEELVA
     NLNEVPEAIR TAVRNNGGGH ANHTFFWTIL SPNGGGQPVG ELATAIEAKF GSFDAFKEEF
     AKAGATRFGS GWAWLVVNNG ELEVTSTPNQ DSPLTEGKTP VIGLDVWEHA YYLNYQNRRP
     DYIGAFWNVV DWNAAEKRYQ EAK
//
DBGET integrated database retrieval system