ID CSEA_STRAW Reviewed; 217 AA.
AC Q82EB0;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-JAN-2008, sequence version 2.
DT 27-MAR-2024, entry version 78.
DE RecName: Full=Lipoprotein CseA;
DE Flags: Precursor;
GN Name=cseA; OrderedLocusNames=SAV_4705;
OS Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS 14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=227882;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL
RC 8165 / MA-4680;
RX PubMed=11572948; DOI=10.1073/pnas.211433198;
RA Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA Sakaki Y., Hattori M.;
RT "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT deducing the ability of producing secondary metabolites.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL
RC 8165 / MA-4680;
RX PubMed=12692562; DOI=10.1038/nbt820;
RA Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA Sakaki Y., Hattori M., Omura S.;
RT "Complete genome sequence and comparative analysis of the industrial
RT microorganism Streptomyces avermitilis.";
RL Nat. Biotechnol. 21:526-531(2003).
CC -!- FUNCTION: May be involved in the stabilization of the cell envelope or
CC may interact with the sensor protein CseC to modulate its activity, in
CC response to cell envelope stress. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAC72417.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; BA000030; BAC72417.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_037652360.1; NZ_JZJK01000054.1.
DR AlphaFoldDB; Q82EB0; -.
DR KEGG; sma:SAVERM_4705; -.
DR eggNOG; ENOG502ZWYH; Bacteria.
DR HOGENOM; CLU_078792_0_0_11; -.
DR OrthoDB; 3824278at2; -.
DR Proteomes; UP000000428; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW Signal.
FT SIGNAL 1..34
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT CHAIN 35..217
FT /note="Lipoprotein CseA"
FT /id="PRO_0000314478"
FT REGION 39..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 192..217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT LIPID 35
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT LIPID 35
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ SEQUENCE 217 AA; 22396 MW; DCA79EFD36DDFCEE CRC64;
MRGLGTESLR ARGALKAAIA AVAGLAVLGL SVSACGTGGT GARDEGPAGS DSVAAGAATP
TVSPSKAPKS VDAVKLVKDD PKVGAAVKRA LKPCVADEYP VDVSYGDLTG GSADDIVVNV
MTCGDAVGIG SYVYREQGHS YENVFRAEEP PVYAEIDRGE LVVTQQMYEK DDPVSYPSSE
EVITYSWSAN RFSEESRTHT EYSNAVGGTD SATPAPN
//
