ID Q82N30_STRAW Unreviewed; 346 AA.
AC Q82N30;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 115.
DE SubName: Full=ATP/GTP-binding protein {ECO:0000313|EMBL:BAC69183.1};
GN ORFNames=SAVERM_1473 {ECO:0000313|EMBL:BAC69183.1};
OS Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS 14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=227882 {ECO:0000313|EMBL:BAC69183.1, ECO:0000313|Proteomes:UP000000428};
RN [1] {ECO:0000313|EMBL:BAC69183.1, ECO:0000313|Proteomes:UP000000428}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX PubMed=11572948; DOI=10.1073/pnas.211433198;
RA Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA Sakaki Y., Hattori M.;
RT "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT deducing the ability of producing secondary metabolites.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN [2] {ECO:0000313|EMBL:BAC69183.1, ECO:0000313|Proteomes:UP000000428}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 /
RC NRRL 8165 / MA-4680 {ECO:0000313|Proteomes:UP000000428};
RX PubMed=12692562; DOI=10.1038/nbt820;
RA Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA Sakaki Y., Hattori M., Omura S.;
RT "Complete genome sequence and comparative analysis of the industrial
RT microorganism Streptomyces avermitilis.";
RL Nat. Biotechnol. 21:526-531(2003).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the Nudix hydrolase family.
CC {ECO:0000256|ARBA:ARBA00005582}.
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DR EMBL; BA000030; BAC69183.1; -; Genomic_DNA.
DR RefSeq; WP_010982911.1; NZ_JZJK01000086.1.
DR AlphaFoldDB; Q82N30; -.
DR KEGG; sma:SAVERM_1473; -.
DR eggNOG; COG0645; Bacteria.
DR eggNOG; COG1051; Bacteria.
DR HOGENOM; CLU_799046_0_0_11; -.
DR OrthoDB; 9799092at2; -.
DR Proteomes; UP000000428; Chromosome.
DR CDD; cd02883; Nudix_Hydrolase; 1.
DR Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR020476; Nudix_hydrolase.
DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR InterPro; IPR000086; NUDIX_hydrolase_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR43046; GDP-MANNOSE MANNOSYL HYDROLASE; 1.
DR PANTHER; PTHR43046:SF12; GDP-MANNOSE MANNOSYL HYDROLASE; 1.
DR Pfam; PF13671; AAA_33; 1.
DR Pfam; PF00293; NUDIX; 1.
DR PRINTS; PR00502; NUDIXFAMILY.
DR SUPFAM; SSF55811; Nudix; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51462; NUDIX; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000428}.
FT DOMAIN 199..329
FT /note="Nudix hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS51462"
SQ SEQUENCE 346 AA; 37976 MW; 598572DA56F0487C CRC64;
MIVWINGAFG AGKTTTAREL IELIPNSALF DPEVIGGALT HLLPPKRLAE VGDFQDLPIW
RRLVVDTAAA MLADLGGVLV VPMTLLRQEY RDEIFGGLAS RRIPVRHVLL APAETILRER
IAEREIPADL ADGEMRVRQW SYDHIEPYRA ALAAWLTADA HPVDTSALTP YETALRIAEA
VRTGDAPACD IVQTPEPTAE TLAAGVLLFD EQDRVLLVDP TYKAGWEFPG GVVEPGEAPA
RAGMREVAEE TGIRLDEVPR LLVVDWEAPV PPGYGGLRFL FDGGLLDSHE AGRLVLPGPE
LRDWRFVTEE EAAGLLPPVR YERLRWALRA RERGAALYLE AGIPLG
//
