ID Q832S3_ENTFA Unreviewed; 380 AA.
AC Q832S3;
DT 01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT 01-JUN-2003, sequence version 1.
DT 27-MAR-2024, entry version 102.
DE SubName: Full=Site-specific recombinase, phage integrase family {ECO:0000313|EMBL:AAO81878.1};
GN OrderedLocusNames=EF_2145 {ECO:0000313|EMBL:AAO81878.1};
OS Enterococcus faecalis (strain ATCC 700802 / V583).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=226185 {ECO:0000313|EMBL:AAO81878.1, ECO:0000313|Proteomes:UP000001415};
RN [1] {ECO:0000313|EMBL:AAO81878.1, ECO:0000313|Proteomes:UP000001415}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700802 / V583 {ECO:0000313|Proteomes:UP000001415};
RX PubMed=12663927; DOI=10.1126/science.1080613;
RA Paulsen I., Banerjei L., Myers G.S.A., Nelson K.E., Seshadri R., Read T.D.,
RA Fouts D.E., Eisen J.A., Gill S.R., Heidelberg J.F., Tettelin H.,
RA Dodson R.J., Umayam L., Brinkac L., Beanan M., Daugherty S., DeBoy R.T.,
RA Durkin S., Kolonay J., Madupu R., Nelson W., Vamathevan J., Tran B.,
RA Upton J., Hansen T., Shetty J., Khouri H., Utterback T., Radune D.,
RA Ketchum K.A., Dougherty B.A., Fraser C.M.;
RT "Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus
RT faecalis.";
RL Science 299:2071-2074(2003).
CC -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC {ECO:0000256|ARBA:ARBA00008857}.
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DR EMBL; AE016830; AAO81878.1; -; Genomic_DNA.
DR RefSeq; NP_815808.1; NC_004668.1.
DR RefSeq; WP_010774224.1; NZ_KE136528.1.
DR AlphaFoldDB; Q832S3; -.
DR STRING; 226185.EF_2145; -.
DR EnsemblBacteria; AAO81878; AAO81878; EF_2145.
DR KEGG; efa:EF2145; -.
DR PATRIC; fig|226185.45.peg.1383; -.
DR eggNOG; COG0582; Bacteria.
DR HOGENOM; CLU_027562_17_6_9; -.
DR Proteomes; UP000001415; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR CDD; cd01189; INT_ICEBs1_C_like; 1.
DR Gene3D; 1.10.150.130; -; 1.
DR Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR013762; Integrase-like_cat_sf.
DR InterPro; IPR002104; Integrase_catalytic.
DR InterPro; IPR010998; Integrase_recombinase_N.
DR InterPro; IPR025269; SAM-like_dom.
DR PANTHER; PTHR30629; PROPHAGE INTEGRASE; 1.
DR PANTHER; PTHR30629:SF2; PROPHAGE INTEGRASE INTS-RELATED; 1.
DR Pfam; PF13102; Phage_int_SAM_5; 1.
DR Pfam; PF00589; Phage_integrase; 1.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE 3: Inferred from homology;
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000001415}.
FT DOMAIN 171..373
FT /note="Tyr recombinase"
FT /evidence="ECO:0000259|PROSITE:PS51898"
SQ SEQUENCE 380 AA; 44279 MW; 758876C2853C4C39 CRC64;
MAEPKKLANG KWQLRFKYKD SITNEWKNKM ITRSTKKACR DAETEFKSKI MRGENTEAIK
LLDFYDIWVD TFKKNKVSAG RMQKIALTRK NLHDFFGDKQ LLKGVTKVKY QQWINWLAKP
GNINEKGLAV ETVSNRHNIV KSMFLEALDM QYIHSNPTRN IKLTGQVPEK KSNKTISIDD
LTKFKEALLS RENTTSKYFI LVQLYTGARY QEVAALTWDS IDESNEVIKI KNAYKYDAGQ
YRIGPTKSEA GVRNIDVPSS LFYYLKKYEM EQKKKILRGD LRNPQNFAFV SKKNSWPISN
SSVNKYIKET CELANIERIS SHSFRHARSD LLILAEADPI YIKTQLGHKE IIQSYEYASA
TEANRKKNKE KYENKYKDIL
//
